Activation of human platelets by peroxovanadate is associated with tyrosine phosphorylation of phospholipase C gamma and formation of inositol phosphates

scientific article published on March 1993

Activation of human platelets by peroxovanadate is associated with tyrosine phosphorylation of phospholipase C gamma and formation of inositol phosphates is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ2900471
P932PMC publication ID1132297
P698PubMed publication ID8452536
P5875ResearchGate publication ID14745847

P50authorSteve P. WatsonQ37383398
P2093author name stringWalker TR
Blake RA
P2860cites workMembrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human plateletsQ24323304
The action of the protein kinase C inhibitor, staurosporine, on human platelets. Evidence against a regulatory role for protein kinase C in the formation of inositol trisphosphate by thrombinQ28361275
Synergy between Ca2+ and protein kinase C is the major factor in determining the level of secretion from human plateletsQ28609210
Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitroQ28625928
Binding of Transforming Protein, P47 gag-crk , to a Broad Range of Phosphotyrosine-containing ProteinsQ30195844
Thrombin treatment induces rapid changes in tyrosine phosphorylation in plateletsQ33834719
Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in plateletsQ33846628
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activityQ35589675
Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteinsQ36224276
Inositol phospholipids-specific phospholipase C: interaction of the gamma 1 isoform with tyrosine kinaseQ36441714
Platelet tyrosine-specific protein phosphorylation is regulated by thrombinQ36844443
The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinityQ37378589
Thiazolidine-diones. Biochemical and biological activity of a novel class of tyrosine protein kinase inhibitors.Q41710060
Effects of substitution of threonine 654 of the epidermal growth factor receptor on epidermal growth factor-mediated activation of phospholipase C.Q42832713
A diacylglycerol kinase inhibitor, R59022, potentiates secretion by and aggregation of thrombin-stimulated human plateletsQ42855968
Regulation of Phospholipase C-γ1 by Profilin and Tyrosine PhosphorylationQ43486850
Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine PhosphorylationQ44763188
Effects of gelsolin on human platelet cytosolic phosphoinositide-phospholipase C isozymesQ48493871
Potent selective inhibitors of protein kinase CQ57005076
Ionophore A23187-induced protein-tyrosine phosphorylation of human platelets: Possible synergism between Ca2+ mobilization and protein kinase C activationQ67680997
Tyrosine kinase blockers: new platelet activation inhibitorsQ68397556
Protein-tyrosine phosphorylation and aggregation of intact human platelets by vanadate with H2O2Q68857698
Thrombin and collagen induce rapid phosphorylation of a common set of cellular proteins on tyrosine in human plateletsQ69061256
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)471-475
P577publication date1993-03-01
P1433published inBiochemical JournalQ864221
P1476titleActivation of human platelets by peroxovanadate is associated with tyrosine phosphorylation of phospholipase C gamma and formation of inositol phosphates
P478volume290 ( Pt 2)

Reverse relations

cites work (P2860)
Q33650943Activation of phospholipase C gamma 1 protects renal arteriolar VSMCs from H2O2-induced cell death
Q47927817Collagen receptor signalling in platelets: extending the role of the ITAM.
Q43681994Enhanced sensitivity of insulin-resistant adipocytes to vanadate is associated with oxidative stress and decreased reduction of vanadate (+5) to vanadyl (+4).
Q24528267Evidence for a role for tyrosine phosphorylation of phospholipase C gamma 2 in collagen-induced platelet cytosolic calcium mobilization
Q63408044Evidence of a Role for SHP-1 in Platelet Activation by the Collagen Receptor Glycoprotein VI
Q63408114Fcγ receptor II stimulated formation of inositol phosphates in human platelets is blocked by tyrosine kinase inhibitors and associated with tyrosine phosphorylation of the receptor
Q29347516G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2
Q43078743Mitochondrial diacylglycerol initiates protein-kinase D1-mediated ROS signaling
Q41163144Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syndecan-1.
Q42097119Phospholipase C-gamma1 is required for cell survival in oxidative stress by protein kinase C.
Q45349842Phospholipase C-γ2 via p38 and ERK1/2 MAP kinase mediates diperoxovanadate-asparagine induced human platelet aggregation and sCD40L release.
Q33595625Redox regulation of cellular signalling
Q41811254Regulation of cytosolic calcium by collagen in single human platelets
Q42230490Regulation of vascular and gastric smooth muscle contractility by pervanadate
Q43660364Role of p38 MAP kinase in diperoxovanadate-induced phospholipase D activation in endothelial cells
Q42822188Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc gamma-IIA receptor
Q42087694The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts
Q41079341The use of collagen-based model peptides to investigate platelet-reactive sequences in collagen
Q37532332The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signaling in cytosol-depleted RBL-2H3 and HL-60 cells
Q24530162Thrombin activation of human platelets dissociates a complex containing gelsolin and actin from phosphatidylinositide-specific phospholipase Cgamma1
Q41857707Thrombin-induced translocation of GLUT3 glucose transporters in human platelets
Q42834042Tyrosine phosphorylation of P-selectin in intact platelets and in a disulphide-linked complex with immunoprecipitated pp60c-src
Q28137651Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets
Q28202880Tyrosine phosphorylation-dependent activation of NF-kappa B. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases
Q43701554cAMP potentiates H(2)O(2)-induced ERK1/2 phosphorylation without the requirement for MEK1/2 phosphorylation