Disruption of cytoskeletal integrity impairs Gi-mediated signaling due to displacement of Gi proteins

scientific article published on August 2001

Disruption of cytoskeletal integrity impairs Gi-mediated signaling due to displacement of Gi proteins is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1083/JCB.200103011
P932PMC publication ID2196465
P698PubMed publication ID11514589
P5875ResearchGate publication ID25871502

P2093author name stringY Fan
J Han
R Fässler
T Schöneberg
B K Fleischmann
S Xue
J Hescheler
W Bloch
M Walther
G Ji
K Addicks
Z J Lu
P2860cites workAnchoring proteins confer G protein sensitivity to an inward-rectifier K(+) channel through the GK domainQ24529991
PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membraneQ24563377
Adenylyl cyclase inhibition and altered G protein subunit expression and ADP-ribosylation patterns in tissues and cells from Gi2 alpha-/-miceQ28584699
Lack of muscarinic regulation of Ca(2+) channels in G(i2)alpha gene knockout mouse heartsQ28591533
Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrinQ28591675
The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardiumQ29614435
The caveolae membrane systemQ29614726
Directed actin polymerization is the driving force for epithelial cell-cell adhesionQ29618861
cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonistsQ33617881
Close association of the alpha subunits of Gq and G11 G proteins with actin filaments in WRK1 cells: relation to G protein-mediated phospholipase C activationQ33978093
Ion channel regulation by G proteins.Q34288887
Direct or C5a-induced activation of heterotrimeric Gi2 proteins in human neutrophils is associated with interaction between formyl peptide receptors and the cytoskeleton.Q34384515
Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currentsQ34540878
Modulation of calcium current in arteriolar smooth muscle by alphav beta3 and alpha5 beta1 integrin ligandsQ36255492
Integrin-mediated signals regulated by members of the rho family of GTPasesQ36256316
Targeted inactivation of alphai2 or alphai3 disrupts activation of the cardiac muscarinic K+ channel, IK+Ach, in intact cellsQ36297627
Intracellular Ca2+ oscillations drive spontaneous contractions in cardiomyocytes during early developmentQ36419308
Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase.Q37440090
Regulation of cardiac L-type calcium current by phosphorylation and G proteinsQ37876714
Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteinsQ38321929
Integrins regulate the linkage between upstream and downstream events in G protein-coupled receptor signaling to mitogen-activated protein kinaseQ40884588
Galpha(i2), Galpha(i3)and Galpha(o) are all required for normal muscarinic inhibition of the cardiac calcium channels in nodal/atrial-like cultured cardiocytesQ40931616
Functional characteristics of ES cell-derived cardiac precursor cells identified by tissue-specific expression of the green fluorescent proteinQ40986055
Beta 1 integrin is essential for teratoma growth and angiogenesisQ41089035
Association of the gamma12 subunit of G proteins with actin filaments.Q41102226
Integrins as signaling molecules and targets for tumor therapyQ41469709
Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic miceQ41610565
Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockersQ41655060
The role of cytoskeletal proteins in cardiomyopathiesQ41713568
The internal and external protein scaffold of the T-tubular system in cardiomyocytesQ42463373
Establishment of beta-adrenergic modulation of L-type Ca2+ current in the early stages of cardiomyocyte developmentQ42467529
Regulation of the L-type Ca2+ channel during cardiomyogenesis: switch from NO to adenylyl cyclase-mediated inhibitionQ42467766
Laminin acts via beta 1 integrin signalling to alter cholinergic regulation of L-type Ca(2+) current in cat atrial myocytesQ42490026
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocystsQ42771254
On the mechanism of histamine induced enhancement of the cardiac Ca2+ currentQ46277014
The cytoskeleton and cell signaling: component localization and mechanical couplingQ47801990
Cardiac specific expression of the green fluorescent protein during early murine embryonic development.Q52181032
Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrinsQ57006559
Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heartQ59068860
Selective coupling of G protein beta gamma complexes to inhibition of Ca2+ channelsQ73954627
Laminin binding to beta1-integrins selectively alters beta1- and beta2-adrenoceptor signalling in cat atrial myocytesQ74176742
Muscarinic and beta-adrenergic regulation of heart rate, force of contraction and calcium current is preserved in mice lacking endothelial nitric oxide synthaseQ74623269
Vinculin, Talin, Integrin alpha6beta1 and laminin can serve as components of attachment complex mediating contraction force transmission from cardiomyocytes to extracellular matrixQ77896162
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
P304page(s)753-761
P577publication date2001-08-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleDisruption of cytoskeletal integrity impairs Gi-mediated signaling due to displacement of Gi proteins
P478volume154

Reverse relations

cites work (P2860)
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Q44942592Extracellular matrix modulates beta2-adrenergic receptor signaling in human airway smooth muscle cells
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Q28573187Integrin receptor activation triggers converging regulation of Cav1.2 calcium channels by c-Src and protein kinase A pathways
Q48975311Perlecan is critical for heart stability.
Q44553562Role of the sensory neuron cytoskeleton in second messenger signaling for inflammatory pain
Q36226810Section I. The cholinergic system

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