| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1032061039 |
| P356 | DOI | 10.1038/NATURE11834 |
| P698 | PubMed publication ID | 23354051 |
| P5875 | ResearchGate publication ID | 235375793 |
| P50 | author | Jin Li | Q6201879 |
| P2093 | author name string | Mao Zhang | |
| Peng Jiang | |||
| Yan Zhang | |||
| Xin Zhang | |||
| Ping Jiang | |||
| Yongxing Cao | |||
| Wei Peng | |||
| Chun-Mei Cao | |||
| Fenghua Liu | |||
| Rui-Ping Xiao | |||
| Xiuqin Zhang | |||
| Fengxiang Lv | |||
| Hong-Kun Wu | |||
| Jiaojiao Guo | |||
| Ruisheng Song | |||
| Shaoshuai Meng | |||
| Yanbin Pi | |||
| P2860 | cites work | Insulin signalling and the regulation of glucose and lipid metabolism | Q24292020 |
| The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation | Q24315972 | ||
| Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha | Q24319974 | ||
| The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase | Q28145635 | ||
| SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2 | Q28201656 | ||
| MG53 nucleates assembly of cell membrane repair machinery. | Q28511885 | ||
| The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha | Q28588941 | ||
| The metabolic syndrome | Q29616309 | ||
| Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects | Q34218011 | ||
| Developmental origins of the metabolic syndrome: prediction, plasticity, and programming | Q36079011 | ||
| Tissue-specific roles of IRS proteins in insulin signaling and glucose transport | Q36386892 | ||
| Metabolic syndrome: connecting and reconciling cardiovascular and diabetes worlds | Q36424501 | ||
| Rhesus macaques develop metabolic syndrome with reversible vascular dysfunction responsive to pioglitazone | Q37178240 | ||
| Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading. | Q37302235 | ||
| Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse | Q37376749 | ||
| Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs. | Q37477571 | ||
| Skeletal muscle insulin resistance is the primary defect in type 2 diabetes | Q37624257 | ||
| Insulin receptors of skeletal muscle: Specific insulin binding sites and demonstration of decreased numbers of sites in obese rats | Q39078113 | ||
| The SCF-Fbxo40 Complex Induces IRS1 Ubiquitination in Skeletal Muscle, Limiting IGF1 Signaling | Q39451697 | ||
| Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice | Q39725584 | ||
| Grb10 mediates insulin-stimulated degradation of the insulin receptor: a mechanism of negative regulation | Q40325493 | ||
| Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function | Q41817667 | ||
| Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians | Q43850960 | ||
| Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle | Q45249911 | ||
| Insulin resistance in spontaneously hypertensive rats. Difference in interpretation based on insulin infusion rate or on plasma insulin in glucose clamp studies | Q51656780 | ||
| Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance | Q52540333 | ||
| Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy | Q54332121 | ||
| Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study | Q67521964 | ||
| The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization | Q70196543 | ||
| A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance | Q77652485 | ||
| MG53 constitutes a primary determinant of cardiac ischemic preconditioning | Q84338697 | ||
| P433 | issue | 7437 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | insulin resistance | Q1053470 |
| Insulin receptor | Q14863366 | ||
| Insulin receptor substrate 1 | Q15334111 | ||
| Tripartite motif-containing 72 | Q21991331 | ||
| P304 | page(s) | 375-379 | |
| P577 | publication date | 2013-01-27 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders | |
| P478 | volume | 494 |
| Q90179654 | A knock-in mutation at cysteine 144 of TRIM72 is cardioprotective and reduces myocardial TRIM72 release |
| Q55400599 | An MG53-IRS1-interaction disruptor ameliorates insulin resistance. |
| Q92716002 | Association of GCKR rs780094 polymorphism with circulating lipid levels in type 2 diabetes and hyperuricemia in Uygur Chinese |
| Q89704883 | Biochemical characterization of TRIM72 E3 ligase and its interaction with the insulin receptor substrate 1 |
| Q38592281 | Bone-specific insulin resistance disrupts whole-body glucose homeostasis via decreased osteocalcin activation |
| Q35881667 | Cardioprotection of recombinant human MG53 protein in a porcine model of ischemia and reperfusion injury |
| Q36342097 | Cardiovascular research is thriving in China |
| Q47976670 | DDB1-Mediated CRY1 Degradation Promotes FOXO1-Driven Gluconeogenesis in Liver. |
| Q49960457 | Diabetic Cardiomyopathy: An Update of Mechanisms Contributing to This Clinical Entity |
| Q43178154 | Diabetic cardiomyopathy: catabolism driving metabolism |
| Q38687425 | Diabetic cardiomyopathy: role of the E3 ubiquitin ligase |
| Q58794226 | Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferlin and MG53 |
| Q38833439 | Dual function of MG53 in membrane repair and insulin signaling |
| Q35581794 | Effect of metabolic syndrome on mitsugumin 53 expression and function |
| Q94453077 | Effect of pioglitazone on skeletal muscle lipid deposition in the insulin resistance rat model induced by high fructose diet under AMPK signaling pathway |
| Q33947907 | Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer |
| Q40227877 | Evaluation of common variants in MG53 and the risk of type 2 diabetes and insulin resistance in Han Chinese |
| Q55069705 | Exchanging cardiac phenotype: Is AKT-mediated NHE1 inhibition a permissive switch in physiological hypertrophy? |
| Q97905319 | Four pleiotropic loci associated with fat mass and lean mass |
| Q51401647 | Frontline Science: D1 dopaminergic receptor signaling activates the AMPK-bioenergetic pathway in macrophages and alveolar epithelial cells and reduces endotoxin-induced ALI. |
| Q34124378 | Hydrogen peroxide primes heart regeneration with a derepression mechanism |
| Q53004815 | Identification of PI3K regulatory subunit p55γ as a novel inhibitor of vascular smooth muscle cell proliferation and neointimal formation |
| Q27313507 | Impaired mitochondrial dynamics and bioenergetics in diabetic skeletal muscle |
| Q51149463 | Increasing the Level of IRS-1 and Insulin Pathway Sensitivity by Natural Product Carainterol A. |
| Q47135810 | Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways |
| Q47264775 | Inhibition of Macrophage Complement Receptor CRIg by TRIM72 Polarizes Innate Immunity of the Lung |
| Q33556119 | Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation |
| Q54115203 | Insulin receptor plasma membrane levels increased by the progesterone receptor membrane component 1. |
| Q34722516 | Ligand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function. |
| Q37237315 | MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels. |
| Q64241892 | MG 53 Protein Protects Aortic Valve Interstitial Cells From Membrane Injury and Fibrocalcific Remodeling |
| Q90090280 | MG53 does not manifest the development of diabetes in db/db mice |
| Q38617502 | MG53 is dispensable for T-tubule maturation but critical for maintaining T-tubule integrity following cardiac stress. |
| Q41949841 | MG53's new identity. |
| Q36181792 | MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. |
| Q28589862 | MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling |
| Q35915152 | MG53-mediated cell membrane repair protects against acute kidney injury |
| Q36146335 | Membrane Repair: Mechanisms and Pathophysiology. |
| Q40050024 | Metabolic stress-induced cardiomyopathy is caused by mitochondrial dysfunction due to attenuated Erk5 signaling. |
| Q36109269 | Mitoflash altered by metabolic stress in insulin-resistant skeletal muscle |
| Q37563400 | Mitsugumin 53 (MG53) ligase ubiquitinates focal adhesion kinase during skeletal myogenesis |
| Q43110566 | Mitsugumin-53: potential biomarker and therapeutic for myocardial ischemic injury? |
| Q43135175 | Molecular mechanisms of insulin resistance in chronic kidney disease |
| Q34156942 | Muscle wasting: an overview of recent developments in basic research |
| Q34545563 | Myeloperoxidase deletion prevents high-fat diet-induced obesity and insulin resistance |
| Q35442337 | Nedd4 haploinsufficient mice display moderate insulin resistance, enhanced lipolysis, and protection against high-fat diet-induced obesity |
| Q38886538 | Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity. |
| Q35861004 | Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet |
| Q35235799 | Participation of proteasome-ubiquitin protein degradation in autophagy and the activation of AMP-activated protein kinase |
| Q39071297 | Plasma membrane wounding and repair in pulmonary diseases |
| Q33676124 | Posttranslational modification of mitochondrial transcription factor A in impaired mitochondria biogenesis: implications in diabetic retinopathy and metabolic memory phenomenon. |
| Q49887455 | Potential role of MG53 in the regulation of transforming-growth-factor-β1-induced atrial fibrosis and vulnerability to atrial fibrillation |
| Q26767114 | Precision autophagy directed by receptor regulators - emerging examples within the TRIM family |
| Q37021623 | Prospect of gene therapy for cardiomyopathy in hereditary muscular dystrophy |
| Q43114289 | Quasi-Steady-State Analysis based on Structural Modules and Timed Petri Net Predict System's Dynamics: The Life Cycle of the Insulin Receptor |
| Q52654047 | Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking |
| Q33796356 | Reciprocal regulation of endocytosis and metabolism |
| Q89793532 | Regulation of E3 ubiquitin ligases by homotypic and heterotypic assembly |
| Q64109261 | Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolism |
| Q92482655 | Restoration of insulin receptor improves diabetic phenotype in T2DM mice |
| Q38813011 | Role of E3 ubiquitin ligases in insulin resistance |
| Q41450780 | SRSF1 promotes vascular smooth muscle cell proliferation through a Δ133p53/EGR1/KLF5 pathway. |
| Q64234016 | Secreted MG53 From Striated Muscle Impairs Systemic Insulin Sensitivity |
| Q38162987 | Signaling pathways controlling skeletal muscle mass |
| Q52662687 | Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity |
| Q90662760 | Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function |
| Q37397069 | Swimming Exercise Alleviated Insulin Resistance by Regulating Tripartite Motif Family Protein 72 Expression and AKT Signal Pathway in Sprague-Dawley Rats Fed with High-Fat Diet |
| Q43715393 | TRAF6-mediated ubiquitination of APPL1 enhances hepatic actions of insulin by promoting the membrane translocation of Akt. |
| Q34201280 | TRIM72 is required for effective repair of alveolar epithelial cell wounding. |
| Q28088661 | The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins |
| Q52722152 | The beta secretase BACE1 regulates the expression of insulin receptor in the liver |
| Q36902569 | The neuropilin-like protein ESDN regulates insulin signaling and sensitivity |
| Q38924199 | The ubiquitin proteasome system in atrophying skeletal muscle: roles and regulation |
| Q48293194 | Tributyltin in male mice disrupts glucose homeostasis as well as recovery after exposure: mechanism analysis |
| Q48362905 | Ubiquitinated CD36 sustains insulin-stimulated Akt activation by stabilizing insulin receptor substrate 1 in myotubes |
| Q39033646 | Ubiquitination and the Regulation of Membrane Proteins |
| Q38265657 | Ubiquitination in disease pathogenesis and treatment |
| Q37577025 | Uncoupling of increased cellular oxidative stress and myocardial ischemia reperfusion injury by directed sarcolemma stabilization |
| Q35856483 | Uric Acid Produces an Inflammatory Response through Activation of NF-κB in the Hypothalamus: Implications for the Pathogenesis of Metabolic Disorders |
| Q35662277 | Zinc Binding to MG53 Protein Facilitates Repair of Injury to Cell Membranes |
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