scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1083734572 |
P356 | DOI | 10.1038/NATURE21356 |
P932 | PMC publication ID | 5334176 |
P698 | PubMed publication ID | 28178237 |
P50 | author | Vineet Bafna | Q37380360 |
Tomoyuki Koga | Q55590556 | ||
Frank B Furnari | Q56528881 | ||
Doruk Beyter | Q57414828 | ||
Robert J Wechsler-Reya | Q89497608 | ||
P2093 | author name string | Bing Ren | |
Webster K Cavenee | |||
Bin Li | |||
Michael D Taylor | |||
Geoffrey M Wahl | |||
Paul S Mischel | |||
Scott R Vandenberg | |||
David A Nathanson | |||
Harley I Kornblum | |||
Catherine Lee | |||
Sharmeela Kaushal | |||
P Nagesh Rao | |||
Viraj Deshpande | |||
Kristen M Turner | |||
Karen Arden | |||
Jessica Rusert | |||
P2860 | cites work | Initial sequencing and analysis of the human genome | Q21045365 |
Cancer genome landscapes | Q22242276 | ||
Fast and accurate short read alignment with Burrows-Wheeler transform | Q24653853 | ||
The human genome browser at UCSC | Q24672361 | ||
Different Facets of Copy Number Changes: Permanent, Transient, and Adaptive | Q26769649 | ||
Evolution of the cancer genome | Q27020991 | ||
The clonal evolution of tumor cell populations | Q28271546 | ||
Clonal evolution in cancer | Q29547696 | ||
Intra-tumour heterogeneity: a looking glass for cancer? | Q29620149 | ||
Amplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules | Q33585674 | ||
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA. | Q33725972 | ||
ReadDepth: a parallel R package for detecting copy number alterations from short sequencing reads | Q33815928 | ||
Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. | Q34005286 | ||
Accumulation of driver and passenger mutations during tumor progression | Q34276850 | ||
The architecture and evolution of cancer neochromosomes | Q34454339 | ||
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution | Q34457994 | ||
The Emerging Hallmarks of Cancer Metabolism | Q36468964 | ||
Double minute chromosomes can be produced from precursors derived from a chromosomal deletion | Q36786407 | ||
Temporal and spatial evolution of somatic chromosomal alterations: a case-cohort study of Barrett's esophagus | Q37524048 | ||
Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity | Q37592617 | ||
Pan-cancer patterns of somatic copy number alteration | Q37666205 | ||
Recent progress in understanding mechanisms of mammalian DNA amplification | Q38648620 | ||
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure | Q39680216 | ||
Pan-cancer analysis of the extent and consequences of intratumor heterogeneity. | Q40139573 | ||
Gene amplification in cultured animal cells | Q40182130 | ||
A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration | Q41696612 | ||
Extrachromosomal driver mutations in glioblastoma and low-grade glioma | Q42105308 | ||
Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons | Q42691642 | ||
Mitotic segregation of viral and cellular acentric extrachromosomal molecules by chromosome tethering. | Q45988398 | ||
Gene amplification and drug resistance in cultured murine cells. | Q52430373 | ||
Frequency of double minute chromosomes and combined cytogenetic abnormalities and their characteristics. | Q53287308 | ||
SELECTION OF CHROMOSOMAL VARIANT IN AMETHOPTERIN-RESISTANT SUBLINES OF LEUKEMIA L1210 WITH INCREASED LEVELS OF DIHYDROFOLATE REDUCTASE | Q76545767 | ||
P433 | issue | 7643 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 122-125 | |
P577 | publication date | 2017-02-08 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity | |
P478 | volume | 543 |
Q58714444 | Q58714444 |
Q64069332 | A Systematic Pan-Cancer Analysis of Genetic Heterogeneity Reveals Associations with Epigenetic Modifiers |
Q57799991 | A call to arms: Unifying the fight against resistance |
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Q49043341 | MYC-containing amplicons in acute myeloid leukemia: Genomic structures, evolution, and transcriptional consequences |
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Q47315881 | Modulating secreted components of tumor microenvironment: A masterstroke in tumor therapeutics. |
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Q46217495 | Rebuilding Chromosomes After Catastrophe: Emerging Mechanisms of Chromothripsis. |
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