Inhibition of telomerase activity by HDV ribozyme in cancers

scientific article published on 6 January 2011

Inhibition of telomerase activity by HDV ribozyme in cancers is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1023750677
P356DOI10.1186/1756-9966-30-1
P932PMC publication ID3024244
P698PubMed publication ID21208462
P5875ResearchGate publication ID49730942

P2093author name stringYingying Lu
Yanjing Gao
Junchao Gu
Dachuan Jin
Mengbiao Yuan
P2860cites workResistance to apoptosis in human cells conferred by telomerase function and telomere stabilityQ22003740
Mammalian telomeres end in a large duplex loopQ22009893
Inhibition of telomerase in tumor cells by ribozyme targeting telomerase RNA component.Q53456882
Functional reconstitution of wild-type and mutant Tetrahymena telomeraseQ71650294
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblastsQ73311217
Telomerase activity is elevated in early S phase in hamster cellsQ73381615
Expression of telomerase inhibits hydroxyl radical-induced apoptosis in normal telomerase negative human lung fibroblastsQ73408019
Design and properties of trans-acting HDV ribozymes with extended substrate recognition regionsQ73596588
Effect of antisense human telomerase RNA transfection on the growth of human gastric cancer cell linesQ74525539
Attenuation of telomerase activity by hammerhead ribozyme targeting human telomerase RNA induces growth retardation and apoptosis in human breast tumor cellsQ81025165
Catalytic core structure of the trans-acting HDV ribozyme is subtly influenced by sequence variation outside the coreQ83973698
A telomerase component is defective in the human disease dyskeratosis congenitaQ22010917
Cell cycle-regulated trafficking of human telomerase to telomeresQ24540240
Specific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
Creation of human tumour cells with defined genetic elementsQ28141602
The RNA component of human telomeraseQ28288330
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.Q28366118
A physical and functional constituent of telomerase anchor siteQ34049648
Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for functionQ34400229
Telomerase inhibition, oligonucleotides, and clinical trialsQ34535686
Detailed analysis of base preferences at the cleavage site of a trans-acting HDV ribozyme: a mutation that changes cleavage site specificityQ34627500
Analysis of the cleavage reaction of a trans-acting human hepatitis delta virus ribozymeQ34632869
The prognostic molecular markers in hepatocellular carcinomaQ34668320
Detailed analysis of stem I and its 5' and 3' neighbor regions in the trans-acting HDV ribozymeQ34692128
Participation of Survivin in mitotic and apoptotic activities of normal and tumor-derived cellsQ38296509
The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosisQ38311394
Delta ribozyme has the ability to cleave in transan mRNAQ38328786
Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA.Q40528046
Substrate specificity of delta ribozyme cleavageQ41941431
A conserved secondary structure for telomerase RNAQ44060757
A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers.Q44119553
Trans-acting hepatitis delta virus ribozyme: catalytic core and global structure are dependent on the 5' substrate sequenceQ44487430
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P921main subjectribozymeQ205858
P304page(s)1
P577publication date2011-01-06
P1433published inJournal of Experimental & Clinical Cancer ResearchQ13739415
P1476titleInhibition of telomerase activity by HDV ribozyme in cancers
P478volume30

Reverse relations

cites work (P2860)
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Q53842733Cellular prion protein contributes to LS 174T colon cancer cell carcinogenesis by increasing invasiveness and resistance against doxorubicin-induced apoptosis.
Q46838376Combining transarterial chemoembolization with radiofrequency ablation for hepatocellular carcinoma
Q34295000Crotoxin induces apoptosis and autophagy in human lung carcinoma cells in vitro via activation of the p38MAPK signaling pathway
Q54189432Effect of parthenolide on growth and apoptosis regulatory genes of human cancer cell lines.
Q37981986FGF receptor inhibitors: role in cancer therapy
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Q36952559Low glucose dependent decrease of apoptosis and induction of autophagy in breast cancer MCF-7 cells
Q98464929Nanomaterials for Autophagy-Related miRNA-34a Delivery in Cancer Treatment
Q37360409On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts
Q48289081Osthole inhibited TGF β-induced epithelial-mesenchymal transition (EMT) by suppressing NF-κB mediated Snail activation in lung cancer A549 cells.
Q38893584Phenazine-1-carboxamide (PCN) from Pseudomonas sp. strain PUP6 selectively induced apoptosis in lung (A549) and breast (MDA MB-231) cancer cells by inhibition of antiapoptotic Bcl-2 family proteins.
Q41858669Spontaneous regression of transverse colon cancer: a case report
Q36868580Telomerase as a useful target in cancer fighting-the breast cancer case
Q37046392Telomerase downregulation induces proapoptotic genes expression and initializes breast cancer cells apoptosis followed by DNA fragmentation in a cell type dependent manner
Q41771872The antioxidant and chemical properties of Berberis vulgaris and its cytotoxic effect on human breast carcinoma cells.
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