The senescence-associated secretory phenotype promotes benign prostatic hyperplasia

scientific article published on 13 January 2014

The senescence-associated secretory phenotype promotes benign prostatic hyperplasia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.AJPATH.2013.11.015
P932PMC publication ID3936307
P698PubMed publication ID24434012
P5875ResearchGate publication ID259769525

P2093author name stringPatricia Castro
Michael Ittmann
Paz Vital
Susan Tsang
P2860cites workA biomarker that identifies senescent human cells in culture and in aging skin in vivoQ24562644
The hallmarks of agingQ28131641
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressorQ29615559
Inflammatory networks during cellular senescence: causes and consequencesQ33889156
IL-1 induces IGF-dependent epithelial proliferation in prostate development and reactive hyperplasiaQ34171551
Expression and function of pro-inflammatory interleukin IL-17 and IL-17 receptor in normal, benign hyperplastic, and malignant prostate.Q34200792
CXC-type chemokines promote myofibroblast phenoconversion and prostatic fibrosisQ34485215
Prostatic fibrosis, lower urinary tract symptoms, and BPHQ34822091
The functional role of reactive stroma in benign prostatic hyperplasiaQ35231687
Interleukin-1alpha is a paracrine inducer of FGF7, a key epithelial growth factor in benign prostatic hyperplasiaQ35745901
Interleukin-8 is a paracrine inducer of fibroblast growth factor 2, a stromal and epithelial growth factor in benign prostatic hyperplasiaQ35746575
Models of DNA structure achieve almost perfect discrimination between normal prostate, benign prostatic hyperplasia (BPH), and adenocarcinoma and have a high potential for predicting BPH and prostate cancerQ35909640
Molecular and cellular pathogenesis of benign prostatic hyperplasiaQ35947115
The signals and pathways activating cellular senescenceQ36060167
Endocrine fibroblast growth factor FGF19 promotes prostate cancer progressionQ36778095
Altered fibroblast growth factor receptor 4 stability promotes prostate cancer progressionQ36787646
Role of interleukins, IGF and stem cells in BPHQ37416239
The reactive stroma microenvironment and prostate cancer progressionQ38038833
Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium.Q39274516
Cathepsin D and eukaryotic translation elongation factor 1 as promising markers of cellular senescenceQ39844229
Interleukin-1alpha secreted by pancreatic cancer cells promotes angiogenesis and its therapeutic implicationsQ39925057
Elevated epithelial expression of interleukin-8 correlates with myofibroblast reactive stroma in benign prostatic hyperplasiaQ40006835
Replicative senescence: an old lives' tale?Q40968415
Prostatic fibrosis is associated with lower urinary tract symptomsQ41595234
Immortalization of Human Adult Normal Prostatic Epithelial Cells by Liposomes Containing Large T-SV40 GeneQ41667803
Biological characterization of human fibroblast-derived mitogenic factors for human melanocytesQ42080220
Apoptotic versus proliferative activities in human benign prostatic hyperplasiaQ42519683
Modification of expression of stem cell factor by various cytokinesQ42810616
Stromal cells promote angiogenesis and growth of human prostate tumors in a differential reactive stroma (DRS) xenograft model.Q42814631
Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasiaQ47431429
The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms.Q51285272
DNA base modifications and antioxidant enzyme activities in human benign prostatic hyperplasia.Q53465110
Urologic Diseases in America Project: Benign Prostatic HyperplasiaQ57540144
The development of benign prostatic hyperplasia among volunteers in the Normative Aging StudyQ70043674
Fresh tissue harvest for research from prostatectomy specimensQ71658451
Cellular senescence in the pathogenesis of benign prostatic hyperplasiaQ73135522
Morphometric analysis of pediatric and nonhyperplastic prostate glands: evidence that BPH is not a unique stromal processQ73868506
Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasiaQ73930579
Differential expression of interleukin-15, a pro-inflammatory cytokine and T-cell growth factor, and its receptor in human prostateQ77359724
Analysis of cathepsin D forms and their clinical implications in human prostate cancerQ77562420
FGF7 and FGF2 are increased in benign prostatic hyperplasia and are associated with increased proliferationQ78015006
Increased expression of lymphocyte-derived cytokines in benign hyperplastic prostate tissue, identification of the producing cell types, and effect of differentially expressed cytokines on stromal cell proliferationQ78052199
EZC-prostate models offer high sensitivity and specificity for noninvasive imaging of prostate cancer progression and androgen receptor actionQ79734464
Aging-associated changes in gene expression in the ACI rat prostate: Implications for carcinogenesisQ80867603
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P1104number of pages11
P304page(s)721-731
P577publication date2014-01-13
P1433published inThe American Journal of PathologyQ4744259
P1476titleThe senescence-associated secretory phenotype promotes benign prostatic hyperplasia
P478volume184

Reverse relations

cites work (P2860)
Q39434311Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses?
Q34482996From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes
Q90582750Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
Q33793593Oxidative stress promotes benign prostatic hyperplasia
Q92030387Stimulation of Prostate Cells by the Senescence Phenotype of Epithelial and Stromal Cells: Implication for Benign Prostate Hyperplasia

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