Interleukin-12, Dendritic Cells, and the Initiation of Host-protective Mechanisms against Toxoplasma gondii

scientific article published on December 1, 1997

Interleukin-12, Dendritic Cells, and the Initiation of Host-protective Mechanisms against Toxoplasma gondii is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.186.11.1799
P953full work available online athttps://europepmc.org/articles/PMC2199160
https://europepmc.org/articles/PMC2199160?pdf=render
https://rupress.org/jem/article-pdf/186/11/1799/1112549/97-c017.pdf
https://rupress.org/jem/article-pdf/186/11/1799/1683636/97-c017.pdf
P932PMC publication ID2199160
P698PubMed publication ID9417472
P5875ResearchGate publication ID13811732

P2093author name stringP. C. Sayles
L. L. Johnson
P2860cites workIn Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell AreasQ24652833
Gamma interferon-dependent temporary resistance to acute Toxoplasma gondii infection independent of CD4+ or CD8+ lymphocytesQ33617014
CR3-dependent resistance to acute Toxoplasma gondii infection in mice.Q35495536
Intact immune defenses are required for mice to resist the ts-4 vaccine strain of Toxoplasma gondiiQ35510829
Interleukin-12 enhances murine survival against acute toxoplasmosisQ35778829
Emergence of NK1.1+ cells as effectors of IFN-gamma dependent immunity to Toxoplasma gondii in MHC class I-deficient miceQ36362549
Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyer's patchQ36366101
Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hostsQ36394980
A protective role for endogenous tumor necrosis factor in Toxoplasma gondii infectionQ36945212
Endogenous tumor necrosis factor alpha is required for enhanced antimicrobial activity against Toxoplasma gondii and Listeria monocytogenes in recombinant gamma interferon-treated miceQ36972580
Epithelial M cells: gateways for mucosal infection and immunizationQ41075139
T-cell responses to enteric antigens.Q41119094
Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccineQ41133376
Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivoQ41872431
Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivoQ41905685
New insights into the mobilization and phagocytic activity of dendritic cellsQ42142211
Toxoplasma gondii induces a T-independent IFN-gamma response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-alpha.Q43870805
Studies on the role of interleukin-12 in acute murine toxoplasmosisQ44321828
Toxoplasma gondii: evidence for interleukin-12-dependent and-independent pathways of interferon-gamma production induced by an attenuated parasite strainQ44601654
Interferon-gamma: the major mediator of resistance against Toxoplasma gondiiQ45128276
Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondiiQ48464908
Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokinesQ50140448
Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.Q54195040
CD8+ T cells are the major lymphocyte subpopulation involved in the protective immune response to Toxoplasma gondii in miceQ54297083
Detection of Toxoplasma gondii parasitemia by polymerase chain reaction in perorally infected miceQ58811009
Role of L3T4+ and Lyt-2+ T cell subsets in protective immune responses of mice against infection with a low or high virulent strain of Toxoplasma gondiiQ67942160
Tumor necrosis factor-alpha triggers antitoxoplasmal activity of IFN-gamma primed macrophagesQ68011944
Dual regulation of resistance against Toxoplasma gondii infection by Lyt-2+ and Lyt-1+, L3T4+ T cells in miceQ68093960
Isolation and characterization of antigen-presenting dendritic cells from the mouse intestinal lamina propriaQ68419782
Immune response of mice to ingested Toxoplasma gondii: a model of toxoplasma infection acquired by ingestionQ71276726
Early kinetics of Toxoplasma gondii infection in mice infected orally with cysts of an avirulent strainQ72134210
Endotoxin-mediated dendritic cell release from the intestine. Characterization of released dendritic cells and TNF dependenceQ72412476
Exacerbation of toxoplasmosis in neutrophil-depleted miceQ73924352
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectToxoplasma gondiiQ131003
dendritic cellQ506253
P304page(s)1799-1802
P577publication date1997-12-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleInterleukin-12, dendritic cells, and the initiation of host-protective mechanisms against Toxoplasma gondii
Interleukin-12, Dendritic Cells, and the Initiation of Host-protective Mechanisms against Toxoplasma gondii
P478volume186

Reverse relations

cites work (P2860)
Q77387466A Distinct Th1 Immune Response Precedes the Described Th2 Response in Islet Xenograft Rejection
Q47889348A protective role for IL-6 during early infection with Toxoplasma gondii
Q33682531Apoptosis in dendritic cell biology
Q34001166Construction of a single-chain interleukin-12-expressing retroviral vector and its application in cytokine gene therapy against experimental coccidioidomycosis
Q77323598Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo
Q33653670Dendritic cells.
Q33541967Dendritic cells: a link between innate and adaptive immunity
Q78157760Enhanced antigen-presenting activity and tumour necrosis factor-alpha-independent activation of dendritic cells following treatment with Mycobacterium bovis bacillus Calmette-Guérin
Q54017880Establishment of gene-vaccinated skin grafting against Toxoplasma gondii infection in mice
Q41020331Haplotype analysis finds linkage disequilibrium in the IL-12 gene in patients with HCV.
Q35834633Human non-germinal center B cell interleukin (IL)-12 production is primarily regulated by T cell signals CD40 ligand, interferon gamma, and IL-10: role of B cells in the maintenance of T cell responses.
Q28142802Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning
Q33815034Immune responses to Toxoplasma gondii in the gut.
Q40938855Induction of antigen-specific immunosuppression by CD95L cDNA-transfected 'killer' dendritic cells
Q34646946Interleukin-7 Gene-Modified Dendritic Cells Reduce Pulmonary Tumor Burden in Spontaneous Murine Bronchoalveolar Cell Carcinoma
Q33817903New technologies toward dendritic cell-based cancer immunotherapies
Q77362244Peripheral Blood Dendritic Cells, but Not Monocyte-Derived Dendritic Cells, Can Augment Human NK Cell Function
Q35801712Protective mucosal Th2 immune response against Toxoplasma gondii by murine mesenteric lymph node dendritic cells
Q30426606Role of CXCR3 Ligands in IL-7/IL-7Rα-Fc–Mediated Antitumor Activity in Lung Cancer
Q42556588Toxoplasma gondii infection inhibits Th17-mediated spontaneous development of arthritis in interleukin-1 receptor antagonist-deficient mice

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