Control of mitochondrial function and cell growth by the atypical cadherin Fat1.

scientific article published on 9 November 2016

Control of mitochondrial function and cell growth by the atypical cadherin Fat1. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NATURE20170
P932PMC publication ID5257202
P698PubMed publication ID27828948

P50authorLiang GuoQ41883887
Andras FiserQ61479290
Louis HodgsonQ37838987
P2093author name stringVeronika Miskolci
Rong Hou
Liang Guo
Prameladevi Chinnasamy
Nicholas E S Sibinga
Brian P O'Rourke
Charlene M Dunaway
Longyue L Cao
Mario A Pujato
Dario F Riascos-Bernal
P2860cites workIdentification of variants in the 4q35 gene FAT1 in patients with a facioscapulohumeral dystrophy-like phenotypeQ41536718
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Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins.Q27934000
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The fat-like gene of Drosophila is the true orthologue of vertebrate fat cadherins and is involved in the formation of tubular organs.Q33200357
Low abundance of the matrix arm of complex I in mitochondria predicts longevity in miceQ33626717
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The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes.Q33769230
Mitochondrial protein import motor: the ATPase domain of matrix Hsp70 is crucial for binding to Tim44, while the peptide binding domain and the carboxy-terminal segment play a stimulatory roleQ33911385
Human NDUFS3 gene coding for the 30-kDa subunit of mitochondrial complex I: genomic organization and expressionQ33916125
Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein productsQ34193325
The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemiaQ34235906
Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacyQ34323860
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.Q34324645
Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium fluxQ34333437
The BioPlex Network: A Systematic Exploration of the Human InteractomeQ34485581
The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization.Q34599534
Assessing mitochondrial dysfunction in cells.Q34793639
The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stromaQ35013613
Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function.Q35516613
ABCE1 is a highly conserved RNA silencing suppressorQ35557278
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate SynthesisQ35908707
FAT1 mutations cause a glomerulotubular nephropathyQ35932259
Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.Q36106917
Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytesQ36380848
Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factorQ36808761
β-Catenin C-terminal signals suppress p53 and are essential for artery formationQ37163437
Panorama of ancient metazoan macromolecular complexesQ37283269
How to calculate sample size in animal studies?Q37303624
Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disordersQ37496956
The mitochondrial citrate carrier: metabolic role and regulation of its activity and expression.Q37605032
Functional role of mitochondrial respiratory supercomplexesQ38163695
The function of the respiratory supercomplexes: the plasticity modelQ38173792
Mitochondrial homeostasis: the interplay between mitophagy and mitochondrial biogenesisQ38184198
Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and functionQ38208592
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Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.Q38847446
FAT1 acts as an upstream regulator of oncogenic and inflammatory pathways, via PDCD4, in glioma cellsQ39276818
ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A.Q39337309
Subunits of mitochondrial complex I exist as part of matrix- and membrane-associated subcomplexes in living cellsQ39934113
Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cellsQ40068908
Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-arrayQ40166005
P4510describes a project that usesImageJQ1659584
CytoscapeQ3699942
P433issue7630
P407language of work or nameEnglishQ1860
P921main subjectcell growthQ189159
P304page(s)575-578
P577publication date2016-11-09
P1433published inNatureQ180445
P1476titleControl of mitochondrial function and cell growth by the atypical cadherin Fat1.
P478volume539

Reverse relations

cites work (P2860)
Q57518576A mitochondrial brake on vascular repair
Q47756044ATAD3 proteins: brokers of a mitochondria-endoplasmic reticulum connection in mammalian cells
Q50139173Big roles for Fat cadherins.
Q90078931Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice
Q39365565Configuring a robust nervous system with Fat cadherins
Q47623915Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia
Q90527620How many cadherins do human endothelial cells express?
Q47282078Perceived Racial Discrimination and DNA Methylation Among African American Women in the InterGEN Study
Q38719137Protein interaction screening identifies SH3RF1 as a new regulator of FAT1 protein levels
Q57071593Recombinant chromosome 4 in two fetuses - case report and literature review
Q64074816T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development
Q89893373TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis
Q64253785The Crosstalk Between Cell Adhesion and Cancer Metabolism
Q55094954Tissue-specific activities of the Fat1 cadherin cooperate to control neuromuscular morphogenesis.