| scholarly article | Q13442814 |
| P50 | author | Yoshinao Muro | Q38321686 |
| P2093 | author name string | Nagata Y | |
| Todokoro K | |||
| P2860 | cites work | The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo | Q36530877 |
| Novel alterations in CDK1/cyclin B1 kinase complex formation occur during the acquisition of a polyploid DNA content | Q37379580 | ||
| Selection of an HEL-derived cell line expressing high levels of platelet factor 4. | Q38318667 | ||
| S phase of the cell cycle | Q38718172 | ||
| Biology of megakaryocytes | Q40566822 | ||
| Microtubule organizing centers and gamma-tubulin | Q40744901 | ||
| DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. | Q40793188 | ||
| Kinesin-related proteins at mitotic spindle poles: function and regulation | Q41010875 | ||
| Polyploidization and functional maturation are two distinct processes during megakaryocytic differentiation: involvement of cyclin-dependent kinase inhibitor p21 in polyploidization. | Q41108474 | ||
| Megakaryocytic cell line-specific hyperploidy by cytotoxic necrotizing factor bacterial toxins. | Q41155740 | ||
| The involvement of the rho gene product, a small molecular weight GTP-binding protein, in polyploidization of a human megakaryocytic cell line, CMK. | Q41225198 | ||
| Thrombopoietin Induces Megakaryocyte Differentiation in Hematopoietic Progenitor FDC-P2 Cells | Q41308518 | ||
| Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. | Q41457316 | ||
| cMpl ligand is a humoral regulator of megakaryocytopoiesis | Q41460906 | ||
| Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. | Q41460921 | ||
| Platelet factor 4 gene expression in a human megakaryocytic leukemia cell line (CMK) and its differentiated subclone (CMK11-5). | Q41662565 | ||
| Establishment of a novel human megakaryoblastic leukemia cell line, MEG-01, with positive Philadelphia chromosome | Q42819189 | ||
| Characterization of a new megakaryocytic cell line: the Dami cell | Q44295206 | ||
| Effects of recombinant human thrombopoietin on megakaryocyte colony formation and megakaryocyte ploidy by human CD34+ cells in a serum-free system | Q45096273 | ||
| Cyclin activation of p34cdc2. | Q46130213 | ||
| Endomitosis: A reappraisal | Q52517019 | ||
| The heterogeneity of anticentromere antibodies in immunoblotting analysis | Q68560421 | ||
| Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF | Q69333828 | ||
| Establishment in long term culture of megakaryocytic leukemia cells (EST-IU) from the marrow of a patient with leukemia and a mediastinal germ cell neoplasm | Q70126802 | ||
| Myeloid and megakaryocytic properties of K-562 cell lines | Q70274342 | ||
| Immature megakaryocytes in the mouse: physical characteristics, cell cycle status, and in vitro responsiveness to thrombopoietic stimulatory factor | Q70281548 | ||
| Kinetic analysis of megakaryocyte numbers and ploidy levels in developing colonies from mouse bone marrow cells | Q70475104 | ||
| Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation | Q71017521 | ||
| Megakaryocytopoiesis in rats with special reference to polyploidy | Q71455582 | ||
| Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro | Q71685959 | ||
| The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors | Q71709655 | ||
| Cyclin D3 is essential for megakaryocytopoiesis | Q71789394 | ||
| Immature megakaryocytes in the mouse: in vitro relationship to megakaryocyte progenitor cells and mature megakaryocytes | Q72115960 | ||
| [Expression of cyclin B in megakaryocytes and cells of other hematopoietic lines] | Q72192446 | ||
| A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles | Q24293793 | ||
| Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin | Q24316187 | ||
| A giant nucleopore protein that binds Ran/TC4 | Q24317506 | ||
| Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome | Q24319009 | ||
| A group of interacting yeast DNA replication genes | Q27932669 | ||
| Subcellular localization of yeast CDC46 varies with the cell cycle | Q27940010 | ||
| The cell cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent cdc2 kinase | Q28278405 | ||
| Kinesin proteins: a phylum of motors for microtubule-based motility | Q28293472 | ||
| Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast | Q30032023 | ||
| The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production | Q33491220 | ||
| Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor | Q34311209 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | whole genome duplication | Q63285481 |
| P1104 | number of pages | 9 | |
| P304 | page(s) | 449-457 | |
| P577 | publication date | 1997-10-01 | |
| P1433 | published in | Journal of Cell Biology | Q1524550 |
| P1476 | title | Thrombopoietin-induced polyploidization of bone marrow megakaryocytes is due to a unique regulatory mechanism in late mitosis | |
| P478 | volume | 139 |
| Q28475435 | A senescence-like cell-cycle arrest occurs during megakaryocytic maturation: implications for physiological and pathological megakaryocytic proliferation |
| Q38951017 | AZD1152-HQPA induces growth arrest and apoptosis in androgen-dependent prostate cancer cell line (LNCaP) via producing aneugenic micronuclei and polyploidy. |
| Q35787940 | Altered centrosome structure is associated with abnormal mitoses in human breast tumors |
| Q24318115 | Aurora A, centrosome structure, and the centrosome cycle |
| Q47801362 | BMS-777607 promotes megakaryocytic differentiation and induces polyploidization in the CHRF-288-11 cells |
| Q28591361 | Characterization of a novel kinetochore protein, CENP-H |
| Q35144992 | Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase |
| Q33953731 | Daughter cell assembly in the protozoan parasite Toxoplasma gondii |
| Q30494274 | Direct visualization of the endomitotic cell cycle in living megakaryocytes: differential patterns in low and high ploidy cells |
| Q34997726 | Down-regulation of stathmin expression is required for megakaryocyte maturation and platelet production |
| Q36381910 | Downregulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells |
| Q73703322 | Ectopic expression of cyclin E allows non-endomitotic megakaryoblastic K562 cells to establish re-replication cycles |
| Q40959637 | Ectopic expression of the Aspergillus nidulans mitotic inducer, nimA kinase, in megakaryocytes: effect on polyploidization |
| Q47288480 | Effects of vascular endothelial growth factors and their receptors on megakaryocytes and platelets and related diseases |
| Q28188424 | Endoreplication cell cycles: more for less |
| Q24654063 | Endoreplication: polyploidy with purpose |
| Q28237393 | From polyploidy to aneuploidy, genome instability and cancer |
| Q36915426 | Fundamental differences in endoreplication in mammals and Drosophila revealed by analysis of endocycling and endomitotic cells |
| Q34430748 | Genesis of clone size heterogeneity in megakaryocytic and other hemopoietic colonies: the stochastic model revisited |
| Q38297916 | Heterologous expression of the transcriptional regulator escargot inhibits megakaryocytic endomitosis |
| Q28296251 | Human AIM-1: cDNA cloning and reduced expression during endomitosis in megakaryocyte-lineage cells |
| Q28145074 | Identification of human APC10/Doc1 as a subunit of anaphase promoting complex |
| Q40899370 | Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line. |
| Q40464481 | Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656. |
| Q41012159 | K-252a-induced polyploidization and differentiation of a human megakaryocytic cell line, Meg-J: transient elevation and subsequent suppression of cyclin B1 and cdc2 expression in the process of polyploidization |
| Q74266766 | Kinetics of endomitosis in primary murine megakaryocytes |
| Q36230854 | Mechanisms of thrombopoiesis |
| Q53615029 | Megakaryocyte polyploidization is associated with decreased expression of polo-like kinase (PLK). |
| Q34215516 | Megakaryocytes and beyond: the birth of platelets |
| Q33343081 | Molecular control of megakaryopoiesis and thrombopoiesis |
| Q33897984 | New roles for cyclin E in megakaryocytic polyploidization |
| Q40797341 | Phosphatidylinositol 3-kinase is necessary but not sufficient for thrombopoietin-induced proliferation in engineered Mpl-bearing cell lines as well as in primary megakaryocytic progenitors |
| Q28542559 | Phosphorylation of ribosomal protein S6 kinase 1 at Thr421/Ser424 and dephosphorylation at Thr389 regulates SP600125-induced polyploidization of megakaryocytic cell lines |
| Q50909238 | Pim-1 induced polyploidy but did not affect megakaryocytic differentiation of K562 cells and CD34+ cells from cord blood. |
| Q37254273 | Platelet production by megakaryocytes: protoplatelet theory justifies cytoplasmic fragmentation model |
| Q40423624 | Polyploidization of glia in neural development links tissue growth to blood-brain barrier integrity |
| Q33829619 | Polyploidy: occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet system |
| Q36556321 | Presence of a defect in karyokinesis during megakaryocyte endomitosis |
| Q46822560 | Promoted megakaryocytic differentiation of K562 cells through oxidative stress caused by near ultraviolet irradiation. |
| Q33938189 | Proplatelet formation of megakaryocytes is triggered by autocrine-synthesized estradiol |
| Q40811924 | Psychosine, cytokinesis, and orphan receptors. Unexpected connections |
| Q28512886 | RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules |
| Q24537159 | Regulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidization |
| Q40912139 | SIAH-1 inhibits cell growth by altering the mitotic process |
| Q38697722 | Simultaneous flow cytometric analysis of megakaryocyte polyploidy and a labile intracellular protein using zinc-based fixation. |
| Q44451159 | Stathmin expression and megakaryocyte differentiation: a potential role in polyploidy |
| Q39897230 | Synchronization of interphase events depends neither on mitosis nor on cdk1 |
| Q33411414 | TGFβ-Mediated Downregulation of Thrombopoietin Is Associated With Platelet Decline in Asymptomatic SIV Infection |
| Q37728190 | The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis |
| Q33369405 | The biogenesis of platelets from megakaryocyte proplatelets |
| Q53144772 | The causal role of megakaryocyte–platelet hyperactivity in acute coronary syndromes. |
| Q37874075 | Thrombocytogenesis by megakaryocyte; Interpretation by protoplatelet hypothesis |
| Q78859159 | Thrombopoietin-induced CXC chemokines, NAP-2 and PF4, suppress polyploidization and proplatelet formation during megakaryocyte maturation |
| Q61819548 | Ultrastructural characterization of maturation, platelet release, and senescence of human cultured megakaryocytes |
| Q58486838 | Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle |
| Q38447785 | When bigger is better: the role of polyploidy in organogenesis |
| Q81449654 | p53 deficiency exacerbates pleiotropic mitotic defects, changes in nuclearity and polyploidy in transdifferentiating pancreatic acinar cells |
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