Innate immune regulation of Serratia marcescens-induced corneal inflammation and infection

scientific article published on 25 October 2012

Innate immune regulation of Serratia marcescens-induced corneal inflammation and infection is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1167/IOVS.12-10238
P932PMC publication ID3481604
P698PubMed publication ID23033384
P5875ResearchGate publication ID231864405

P50authorSean PlattQ57619794
P2093author name stringYan Sun
Rong Zhou
Rui Zhang
Eric Pearlman
Loretta Szczotka-Flynn
P2860cites workMal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transductionQ24291653
Serratia marcescens serralysin induces inflammatory responses through protease-activated receptor 2Q24678788
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsQ27860900
Interferon-gamma-induced MD-2 protein expression and lipopolysaccharide (LPS) responsiveness in corneal epithelial cells is mediated by Janus tyrosine kinase-2 activation and direct binding of STAT1 protein to the MD-2 promoterQ35085000
ExoS and ExoT ADP ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival.Q35740028
TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways.Q36083319
Bacterial infections of the cornea (Pseudomonas aeruginosa).Q36722835
Risk of corneal inflammatory events with silicone hydrogel and low dk hydrogel extended contact lens wear: a meta-analysisQ36792478
The epidemiology of contact lens related infiltrates.Q36792482
The type III secretion system of Pseudomonas aeruginosa: infection by injectionQ37397923
Microbial contamination of contact lenses, lens care solutions, and their accessories: a literature reviewQ37695030
Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88Q38483194
Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity.Q39023319
Lipopolysaccharide entry in the damaged cornea and specific uptake by polymorphonuclear neutrophilsQ39514860
Increased resistance of contact lens-related bacterial biofilms to antimicrobial activity of soft contact lens care solutionsQ39584183
MyD88 functions as a negative regulator of TLR3/TRIF-induced corneal inflammation by inhibiting activation of c-Jun N-terminal kinaseQ40040720
Human corneal epithelial cells respond to ocular-pathogenic, but not to nonpathogenic-flagellinQ40258281
Toll-like receptor 3 agonist poly(I:C)-induced antiviral response in human corneal epithelial cellsQ40327809
Toll-like Receptor 5-Mediated Corneal Epithelial Inflammatory Responses toPseudomonas aeruginosaFlagellinQ40631704
A Serratia marcescens OxyR homolog mediates surface attachment and biofilm formationQ41896317
Inhibition of corneal inflammation by the TLR4 antagonist Eritoran tetrasodium (E5564).Q41905068
Biochemical and genetic characterization of arazyme, an extracellular metalloprotease produced from Serratia proteamaculans HY-3.Q42638436
Toll-like receptor 2-mediated expression of beta-defensin-2 in human corneal epithelial cellsQ43148693
Contribution of ExsA-regulated factors to corneal infection by cytotoxic and invasive Pseudomonas aeruginosa in a murine scarification model.Q44562131
Lipopolysaccharide induced acute red eye and corneal ulcersQ44658440
Role of Pseudomonas aeruginosa ExsA in penetration through corneal epithelium in a novel in vivo model.Q44669108
Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammationQ45238776
Predictive factors for corneal infiltrates with continuous wear of silicone hydrogel contact lenses.Q51028243
Serratia marcescens sepsis outbreak in a neonatal intensive care unit.Q51816195
Contact lens-induced peripheral ulcers with extended wear of disposable hydrogel lenses: histopathologic observations on the nature and type of corneal infiltrateQ72992233
Regulation of endotoxin-induced keratitis by PECAM-1, MIP-2, and toll-like receptor 4Q74389397
Outbreak of Serratia marcescens in a neonatal intensive care unit: contaminated unmedicated liquid soap and risk factorsQ83397632
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectSerratia marcescensQ140004
P304page(s)7382-7388
P577publication date2012-10-25
P1433published inInvestigative Ophthalmology Visual ScienceQ6060707
P1476titleInnate immune regulation of Serratia marcescens-induced corneal inflammation and infection
P478volume53

Reverse relations

cites work (P2860)
Q64914779Blowing epithelial cell bubbles with GumB: ShlA-family pore-forming toxins induce blebbing and rapid cellular death in corneal epithelial cells.
Q36137958EepR Mediates Secreted-Protein Production, Desiccation Survival, and Proliferation in a Corneal Infection Model
Q95262140High-mobility group box1 as an amplifier of immune response and target for treatment in Aspergillus fumigatus keratitis
Q37114405Host defense at the ocular surface
Q35745546Identification of SlpB, a Cytotoxic Protease from Serratia marcescens
Q89068542Opposing Effects of IL-1Ra and IL-36Ra on Innate Immune Response to Pseudomonas aeruginosa Infection in C57BL/6 Mouse Corneas
Q39156160Proteomics in the Study of Bacterial Keratitis
Q34089556TLR4 contributes to the host response to Klebsiella intraocular infection.