Therapeutic Approaches for Zika Virus Infection of the Nervous System

scientific article published on 26 September 2017

Therapeutic Approaches for Zika Virus Infection of the Nervous System is …
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scholarly articleQ13442814

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P5530Altmetric DOI10.1007/S13311-017-0575-2
P6179Dimensions Publication ID1091923443
P356DOI10.1007/S13311-017-0575-2
P8608Fatcat IDrelease_dxmf6jvq5bf2jb6kslu6joycoi
P953full work available at URLhttps://www.proquest.com/openview/362d72ceea05736deb5f30a729e93089
P4028Google Scholar paper ID14425841214454601321
P7100Lens ID011-683-227-866-568
P7916Mendeley publication ID1e354408-f475-371d-b858-6e7d0228a8b6
P6366Microsoft Academic ID2759315373
P243OCLC control number7250344724
P10283OpenAlex IDW2759315373
P932PMC publication ID5722777
P698PubMed publication ID28952036
P5875ResearchGate publication ID320050701
P7710ScienceOpen publication ID676e6d5b-3747-4535-974e-14a14871e372
P8299Semantic Scholar corpus ID23878046
P4011Semantic Scholar paper IDc16a579b8139b4ed839e35565fb99f3b9ae12e14
P8372Web of Science work ID000417695200019

P50authorRachel P. M. AbramsQ102335686
P2093author name stringAvindra Nath
Jamie Solis
P2860cites workTIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserineQ21131381
Zika virus. I. Isolations and serological specificityQ22240545
Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007Q22241244
Zika virus: a previously slow pandemic spreads rapidly through the AmericasQ22242663
Zika Virus in the Americas — Yet Another Arbovirus ThreatQ22248116
Zika Virus Outbreak on Yap Island, Federated States of MicronesiaQ22250881
A small-molecule dengue virus entry inhibitorQ22309806
Zika virus in Brazil and macular atrophy in a child with microcephalyQ22330676
Detection of Zika virus in salivaQ22330713
Zika virus infections imported to Italy: clinical, immunological and virological findings, and public health implicationsQ22330725
Detection of Zika virus in urineQ22330729
Evidence of perinatal transmission of Zika virus, French Polynesia, December 2013 and February 2014Q22330746
Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014Q22330747
Full-length sequencing and genomic characterization of Bagaza, Kedougou, and Zika virusesQ22330782
Zika virus, a cause of fever in Central Java, IndonesiaQ22330869
Isolation of Zika Virus from Aedes Aegypti Mosquitoes in Malaysia *Q22330876
Zika virus: a report on three cases of human infection during an epidemic of jaundice in NigeriaQ22330904
Zika Virus Associated with MicrocephalyQ22683189
Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control studyQ23012849
Drug repositioning: identifying and developing new uses for existing drugsQ29614779
Composition and three-dimensional architecture of the dengue virus replication and assembly sitesQ29615112
Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment optionsQ29620126
Sofosbuvir for previously untreated chronic hepatitis C infectionQ29620137
Zika virus: high infectious viral load in semen, a new sexually transmitted pathogen?Q30051605
A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 proteaseQ30145558
Pediatric Drug Nitazoxanide: A Potential Choice for Control of ZikaQ30145642
Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonistsQ30145664
Polysulfonate suramin inhibits Zika virus infectionQ30145667
Prospects for a Zika Virus VaccineQ30235612
In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses.Q30381077
Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse modelQ30395163
The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complexQ30484619
Pathogenic flaviviruses.Q31146025
Unwinding the 'Gordian knot' of helicase action.Q31879197
Pregnancy outcome following gestational exposure to azithromycinQ33245155
FDA drug approval summary: azacitidine (5-azacytidine, Vidaza) for injectable suspensionQ33365592
Palbociclib in Hormone-Receptor-Positive Advanced Breast CancerQ33423263
Proteasome inhibitors: a novel class of potent and effective antitumor agents.Q33864458
Bromocriptine mesylate: FDA-approved novel treatment for type-2 diabetesQ33874067
Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.Q34040052
Acute myelitis due to Zika virus infectionQ23014548
Infectious Zika viral particles in breastmilkQ23038269
The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection ModelQ23309956
The 3.8 Å resolution cryo-EM structure of Zika virusQ23680595
Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective AntibodyQ24067948
Structure of the thermally stable Zika virusQ24082710
Effect of administration of antihelminthics for soil-transmitted helminths during pregnancyQ24187087
Emergence of Congenital Zika Syndrome: Viewpoint From the Front LinesQ24261097
Nucleoside inhibitors of Zika virusQ24278770
The crystal structure of Zika virus helicase: basis for antiviral drug designQ24332542
Mefloquine safety and tolerability in pregnancy: a systematic literature reviewQ24599164
3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitroQ24609215
The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemicQ24655011
Endemic paragonimiasis in AfricaQ24655333
Structure of dengue virus: implications for flavivirus organization, maturation, and fusionQ24736810
Pathology of congenital Zika syndrome in Brazil: a case seriesQ25139131
Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitorQ25707171
The clinically approved antiviral drug sofosbuvir impairs Brazilian zika virus replicationQ25707196
Structure of the NS3 helicase from Zika virusQ26247146
Suspected Female-to-Male Sexual Transmission of Zika Virus - New York City, 2016Q26247236
A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus InfectionQ26252076
Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical TransmissionQ26252081
Zika virus in the female genital tractQ26252503
Complete Genome Sequences of Three Historically Important, Spatiotemporally Distinct, and Genetically Divergent Strains of Zika Virus: MR-766, P6-740, and PRVABC-59Q26484330
Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial GliaQ26693468
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screenQ26747306
Flavivirus cell entry and membrane fusionQ26852458
Flavivirus entry receptors: an updateQ26866329
Structural basis of Zika virus helicase in recognizing its substratesQ26970833
Nitazoxanide: a first-in-class broad-spectrum antiviral agentQ27021914
Adenosine Analog NITD008 Is a Potent Inhibitor of Zika VirusQ27463110
Mechanisms of activation and inhibition of Zika virus NS2B-NS3 proteaseQ27463132
Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virusQ27468627
Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface EpitopesQ27477610
A ligand-binding pocket in the dengue virus envelope glycoproteinQ27477685
Proteolytic activation of tick-borne encephalitis virus by furinQ27480892
Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 proteinQ27487462
Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesisQ27490193
An adenosine nucleoside inhibitor of dengue virusQ27490481
Structure of the immature dengue virus at low pH primes proteolytic maturationQ27650165
The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolutionQ27730234
Structure of the NS2B-NS3 protease from Zika virus after self-cleavageQ27869770
The FDA-approved drug sofosbuvir inhibits Zika virus infectionQ27924226
Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymeraseQ27924228
Antiviral activities of selected antimalarials against dengue virus type 2 and Zika virusQ27924733
Structures of NS5 Methyltransferase from Zika VirusQ27928070
Crystal structure of unlinked NS2B-NS3 protease from Zika virusQ27980324
Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assayQ27980548
2,8-bis(trifluoromethyl)quinoline analogs show improved anti-Zika virus activity, compared to mefloquineQ28114553
Structural Insight into NS5 of Zika Virus Leading to the Discovery of MTase InhibitorsQ28114685
The Zika virus methyltransferase: structure and functions for drug design perspectivesQ28114691
Extended substrate specificity and first potent irreversible inhibitor/activity-based probe design for Zika virus NS2B-NS3 proteaseQ28119320
Zika virus cell tropism in the developing human brain and inhibition by azithromycinQ28119685
The risk associated with aprotinin in cardiac surgeryQ28293732
Niclosamide is a proton carrier and targets acidic endosomes with broad antiviral effectsQ28484821
Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosidesQ28485227
Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunityQ28534057
Identification of three antiviral inhibitors against Japanese encephalitis virus from library of pharmacologically active compounds 1280Q28536473
Proteasome Inhibition Suppresses Dengue Virus Egress in Antibody Dependent InfectionQ28550953
Prices, Costs, and Affordability of New Medicines for Hepatitis C in 30 Countries: An Economic AnalysisQ28552507
Analysis of Ribonucleotide 5’ -Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-dependent RNA Polymerase Using Non-Radioactive Polymerase AssaysQ28581011
Induction of Endogenous Virus and of Thymidine Kinase by Bromodeoxyuridine in Cell Cultures Transformed by Friend VirusQ34052299
The drugs we have and the drugs we need against major helminth infectionsQ34125793
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drugQ34246661
Emerging principles in protease-based drug discoveryQ34282102
Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assaysQ34319607
The history and future of targeting cyclin-dependent kinases in cancer therapyQ34460347
The Medicinal Chemistry of Dengue VirusQ34509221
Targeting proteases: successes, failures and future prospectsQ34563752
Novel benzoxazole inhibitor of dengue virus replication that targets the NS3 helicaseQ34583461
The flavivirus protease as a target for drug discoveryQ34657530
Viral protease inhibitorsQ34892265
Pharmacokinetics of single-dose daptomycin in patients with suspected or confirmed neurological infectionsQ35065838
Novel therapeutic strategy for neurodegeneration by blocking Aβ seeding mediated aggregation in models of Alzheimer's diseaseQ35070249
Distribution of azithromycin into brain tissue, cerebrospinal fluid, and aqueous humor of the eye.Q35123496
A9145, a new adenine-containing antifungal antibiotic: fermentationQ35645889
Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral HelicaseQ35647755
Suramin Inhibits Chikungunya Virus Entry and TransmissionQ35711583
Viral and cellular RNA helicases as antiviral targetsQ36267887
Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile virusesQ36332001
The enzymatic termination of polydeoxynucleotides by 2',3'-dideoxyadenosine triphosphateQ36448864
Concise drug review: azacitidine and decitabineQ36871721
Fetal safety of macrolidesQ36969814
BCX4430 - A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus diseaseQ37077376
Molecular strategies to inhibit the replication of RNA virusesQ37099776
Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entryQ37224249
Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor designQ37473075
Nitazoxanide inhibits the replication of Japanese encephalitis virus in cultured cells and in a mouse modelQ37590577
Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5.Q37698482
The conformational changes of Zika virus methyltransferase upon converting SAM to SAH.Q37716454
Daptomycin: a review of properties, clinical use, drug delivery and resistanceQ37987183
Novel therapies for hepatitis C - one pill fits all?Q38117549
Regulation of flavivirus RNA synthesis and cappingQ38127643
A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetusesQ38157419
High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.Q38157498
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replicationQ28595139
Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika VirusQ28595153
N-(2-(arylmethylimino)ethyl)-7-chloroquinolin-4-amine derivatives, synthesized by thermal and ultrasonic means, are endowed with anti-Zika virus activityQ28595161
Perturbation in the conserved methyltransferase-polymerase interface of flavivirus NS5 differentially affects polymerase initiation and elongationQ28651848
Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitorQ28729749
Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virusQ28733552
Real-Time Assessment of Health-Care Requirements During the Zika Virus Epidemic in MartiniqueQ28804115
Structural features of Zika virus non-structural proteins 3 and -5 and its individual domains in solution as well as insights into NS3 inhibitionQ28804200
The Antigenic Structure of Zika Virus and Its Relation to Other Flaviviruses: Implications for Infection and ImmunoprophylaxisQ28804225
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse ModelQ28950498
The structure of Zika virus NS5 reveals a conserved domain conformationQ29198404
Crystal structure of Zika virus NS5 RNA-dependent RNA polymeraseQ29364910
Increased activity of unlinked Zika virus NS2B/NS3 protease compared to linked Zika virus proteaseQ29365202
Solution conformations of a linked construct of the Zika virus NS2B-NS3 proteaseQ29365272
The crystal structure of Zika virus NS5 reveals conserved drug targetsQ29365336
Structure and function of the Zika virus full-length NS5 proteinQ29365369
Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivoQ38157779
Flavivirus RNA methylationQ38184248
Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors.Q38296304
Effect of Pritelivir Compared With Valacyclovir on Genital HSV-2 Shedding in Patients With Frequent Recurrences: A Randomized Clinical TrialQ38383305
Suramin inhibits chikungunya virus replication through multiple mechanismsQ38859980
Structural basis of Zika virus methyltransferase inhibition by sinefunginQ38867867
Microcephaly and Zika virus infectionQ39404041
Zika virus detection in cerebrospinal fluid from two patients with encephalopathy, Martinique, February 2016.Q39412614
Zika Virus: a re-emerging pathogen with rapidly evolving public health implicationsQ39753281
Development of antiretroviral therapy for the acquired immunodeficiency syndrome and related disorders. A progress reportQ39755409
Substrate selectivity of Dengue and Zika virus NS5 polymerase towards 2'-modified nucleotide analoguesQ40051088
Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor designQ40052562
Sexual transmission of Zika virus in an entirely asymptomatic couple returning from a Zika epidemic area, France, April 2016.Q40057882
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.Q40484115
Fascioliasis: diagnosis, epidemiology and treatmentQ40534360
Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma XenograftQ40763120
Response of human-immunodeficiency-virus-associated neurological disease to 3'-azido-3'-deoxythymidineQ41343118
Helicase-primase inhibitor pritelivir for HSV-2 infectionQ42243140
Severe psychiatric side effects observed during prophylaxis and treatment with mefloquineQ42282207
Substrate profiling of Zika virus NS2B-NS3 protease.Q42998302
Clinical trial: the efficacy and safety of oral PF-03491390, a pancaspase inhibitor - a randomized placebo-controlled study in patients with chronic hepatitis C.Q43159165
Maternal and transplacental pharmacokinetics of azithromycinQ43731956
A phase 2 study of SRT501 (resveratrol) with bortezomib for patients with relapsed and or refractory multiple myelomaQ43887370
Successful treatment of acute fascioliasis with bithionolQ43922035
Pharmacokinetics of ivermectin after maternal or fetal intravenous administration in sheepQ46254066
Stereoselective passage of mefloquine through the blood-brain barrier in the rat.Q48584373
FDA approves 3TC and saquinavir. Food and Drug Administration.Q54155250
Nucleosides. V. The Monomesylates of 1-(2'-Deoxy-β-D-lyxofuranosyl)thymine1,2Q56156635
Pregnancy Outcome Among Twins Conceived After Subfertility Treatment Compared With Natural Twins: A Population-Based StudyQ57744941
Niclosamide treatment of cestodiasis. Clinicial trials in the United StatesQ71449841
Fatal Guillain-Barré syndromeQ74455876
CONTACT PHOTODERMATITIS FROM BITHIONOL. II. CROSS-SENSITIVITIES TO HEXACHLOROPHENE AND SALICYLANILIDESQ76847439
Hepatitis C: staying the courseQ80162597
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectZika virusQ202864
Zika virus infectionQ27043680
P1104number of pages22
P5008on focus list of Wikimedia projectWikiProject Zika CorpusQ54439832
P304page(s)1027-1048
P577publication date2017-09-26
P1433published inNeurotherapeuticsQ15716631
P1476titleTherapeutic Approaches for Zika Virus Infection of the Nervous System
P478volume14

Reverse relations

cites work (P2860)
Q58122069Complementary Mechanisms Potentially Involved in the Pathology of Zika Virus
Q90419101Importance of Zika Virus NS5 Protein for Viral Replication
Q58664017Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide
Q89709681Zika virus-spread, epidemiology, genome, transmission cycle, clinical manifestation, associated challenges, vaccine and antiviral drug development

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