Intercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium

scientific article published on 9 February 2012

Intercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/ATVBAHA.111.244186
P932PMC publication ID3331944
P698PubMed publication ID22328778

P50authorCarmen GarnachoQ39636660
Daniel SerranoQ59692837
P2093author name stringSilvia Muro
Tridib Bhowmick
Rishi Chadha
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Acid Sphingomyelinase Deficiency Attenuates Bleomycin-Induced Lung Inflammation and Fibrosis in MiceQ34625430
Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriersQ34690444
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosisQ34765872
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Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathwayQ36562936
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CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasionQ40565703
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Regulation by fibrinogen and its products of intercellular adhesion molecule-1 expression in human saphenous vein endothelial cellsQ40894631
Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1.Q40923925
VCAM-1 is internalized by a clathrin-related pathway in human endothelial cells but its alpha 4 beta 1 integrin counter-receptor remains associated with the plasma membrane in human T lymphocytesQ41039630
Src phosphorylation of endothelial cell surface intercellular adhesion molecule-1 mediates neutrophil adhesion and contributes to the mechanism of lung inflammationQ42148221
Human vascular endothelial cells are a rich and regulatable source of secretory sphingomyelinase. Implications for early atherogenesis and ceramide-mediated cell signalingQ42450640
Investigation of the cellular uptake of E-Selectin-targeted immunoliposomes by activated human endothelial cellsQ43737317
Membrane ruffling and macropinocytosis in A431 cells require cholesterolQ44040005
Sphingomyelinase and ceramide analogs induce vasoconstriction and leukocyte-endothelial interactions in cerebral venules in the intact rat brain: Insight into mechanisms and possible relation to brain injury and strokeQ44071784
Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to intercellular adhesion molecule 1.Q46027250
Control of intracellular trafficking of ICAM-1-targeted nanocarriers by endothelial Na+/H+ exchanger proteinsQ46813262
ICAM-1 recycling in endothelial cells: a novel pathway for sustained intracellular delivery and prolonged effects of drugs.Q51616072
Endocytosis pathways in endothelium: how many?Q57374695
Cisplatin-Induced Apoptosis Involves Membrane Fluidification via Inhibition of NHE1 in Human Colon Cancer CellsQ57374760
Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domainQ58023267
Delivery of Acid Sphingomyelinase in Normal and Niemann-Pick Disease Mice Using Intercellular Adhesion Molecule-1-Targeted Polymer NanocarriersQ59235035
A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implantsQ73707747
Sphingomyelinase induces lipid microdomain formation in a fluid phosphatidylcholine/sphingomyelin membraneQ77710438
Visualization of actin dynamics during macropinocytosis and exocytosisQ77748464
Protein kinase C (PKC) delta regulates PKCalpha activity in a Syndecan-4-dependent mannerQ77829347
ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surfaceQ78806398
Endothelial cell cortactin coordinates intercellular adhesion molecule-1 clustering and actin cytoskeleton remodeling during polymorphonuclear leukocyte adhesion and transmigrationQ79287551
Lysosomal enzyme delivery by ICAM-1-targeted nanocarriers bypassing glycosylation- and clathrin-dependent endocytosisQ81193915
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
ceramidesQ424213
P304page(s)1178-1185
P577publication date2012-02-09
P1433published inArteriosclerosis, Thrombosis, and Vascular BiologyQ4797542
P1476titleIntercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium
P478volume32

Reverse relations

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