Structural basis for the potent calpain inhibitory activity of peptidyl alpha-ketoacids

scientific article published on July 2008

Structural basis for the potent calpain inhibitory activity of peptidyl alpha-ketoacids is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/JM800182C
P932PMC publication ID2643072
P698PubMed publication ID18636690
P5875ResearchGate publication ID51411125

P2093author name stringJiuyu Liu
Isaac O Donkor
Haregewein Assefa
P2860cites workA Ca(2+) switch aligns the active site of calpainQ27638321
Calpain: novel family members, activation, and physiologic functionQ28273311
The synthesis of ketomethylene pseudopeptide analogues of dipeptide aldehyde inhibitors of calpainQ33177359
A survey of calpain inhibitorsQ34060656
Calpains and diseaseQ36156260
Developments in the design and synthesis of calpain inhibitors.Q36324430
Calcium-activated neutral protease (calpain) system: structure, function, and regulationQ37767409
The graphical determination of Km and KiQ42115081
Calpain inhibition by alpha-ketoamide and cyclic hemiacetal inhibitors revealed by X-ray crystallography.Q42688028
Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicityQ45244063
Novel cell-penetrating alpha-keto-amide calpain inhibitors as potential treatment for muscular dystrophyQ46721993
Stereospecific synthesis of peptidyl alpha-keto amides as inhibitors of calpainQ72153804
Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteasesQ72579390
P433issue14
P407language of work or nameEnglishQ1860
P304page(s)4346-4350
P577publication date2008-07-01
P1433published inJournal of Medicinal ChemistryQ900316
P1476titleStructural basis for the potent calpain inhibitory activity of peptidyl alpha-ketoacids
P478volume51

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cites work (P2860)
Q37857282Calpain inhibitors: a survey of compounds reported in the patent and scientific literature
Q35148702Mechanism of action of thalassospiramides, a new class of calpain inhibitors
Q34194374Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors

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