ATP induces guinea pig gallbladder smooth muscle excitability via the P2Y4 receptor and COX-1 activity.

scientific article published on 24 April 2008

ATP induces guinea pig gallbladder smooth muscle excitability via the P2Y4 receptor and COX-1 activity. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPGI.00043.2008
P932PMC publication ID2921626
P698PubMed publication ID18436624
P5875ResearchGate publication ID5415542

P50authorMark T NelsonQ62668149
P2093author name stringGary M Mawe
Aaron C Bartoo
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Prostaglandins mediate tonic contraction of the guinea pig and human gallbladderQ46267351
Possible involvement of prostaglandins in the action of ATP on guinea-pig uterusQ46305068
Cellular mechanisms of thromboxane A2-mediated contraction in pulmonary veinsQ46554947
Effect of Apamin and Theophylline on Adenosine-5´-Triphosphate-Induced Response of the Guinea Pig GallbladderQ46665573
Spontaneous electrical rhythmicity and the role of the sarcoplasmic reticulum in the excitability of guinea pig gallbladder smooth muscle cellsQ46809155
Role of mitochondria in spontaneous rhythmic activity and intracellular calcium waves in the guinea pig gallbladder smooth muscleQ46874573
Cholesterol inhibits spontaneous action potentials and calcium currents in guinea pig gallbladder smooth muscleQ46881692
Human cholecystitis is associated with increased gallbladder prostaglandin I2 and prostaglandin E2 synthesisQ50173157
Ionic basis of the action potential of guinea pig gallbladder smooth muscle cells.Q51650168
Enhanced Thromboxane Receptor-Mediated Responses and Impaired Endothelium-Dependent Relaxation in Human Corpus Cavernosum from Diabetic Impotent Men: Role of Protein Kinase C ActivityQ57702979
Protein kinase A mediates activation of ATP-sensitive K+ currents by CGRP in gallbladder smooth muscleQ72761938
Inhibitory effect of bile salts on gallbladder smooth muscle contractility in the guinea pig in vitroQ73309532
ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes--a possible sensory mechanism?Q74017496
Mechanisms underlying ATP-induced endothelium-dependent contractions in the SHR aortaQ79382059
Morphological and physiological evidence for interstitial cell of Cajal-like cells in the guinea pig gallbladderQ79493672
Kinetics of urothelial ATP releaseQ83101551
International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapyQ24629255
Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.Q27863328
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Regulation of pacemaker frequency in the murine gastric antrumQ28344417
Stimulation of ATP secretion in the liver by therapeutic bile acidsQ28345188
The effects of P2Y receptor agonists and adenosine on prostaglandin production by the guinea-pig uterusQ28346483
Polarized expression and function of P2Y ATP receptors in rat bile duct epitheliaQ28565286
Recovery of skeletal muscle mass after extensive injury: positive effects of increased contractile activityQ28579697
Effect of indomethacin on gallbladder inflammation and contractility during acute cholecystitisQ31952372
Calcium waves in intact guinea pig gallbladder smooth muscle cells.Q33243950
Effects of long term hydrophilic bile acid therapy on in vitro contraction of gallbladder muscle strips in patients with cholesterol gallstonesQ34606068
Extended pharmacological profiles of rat P2Y2 and rat P2Y4 receptors and their sensitivity to extracellular H+ and Zn2+ ionsQ35045909
Evidence for P2Y1, P2Y2, P2Y6 and atypical UTP-sensitive receptors coupled to rises in intracellular calcium in mouse cultured superior cervical ganglion neurons and gliaQ35047775
Chemical mediators of gallbladder dysmotilityQ35848159
Historical review: ATP as a neurotransmitterQ36400069
Purine and pyrimidine receptorsQ36765468
Coactivation of capacitative calcium entry and L-type calcium channels in guinea pig gallbladder.Q39674424
Extracellular nucleotides induce COX-2 up-regulation and prostaglandin E2 production in human A549 alveolar type II epithelial cellsQ40137044
Key role for constitutive cyclooxygenase-2 of MDCK cells in basal signaling and response to released ATP.Q40794025
Synthetic pathways of gallbladder mucosal prostanoids: the role of cyclooxygenase-1 and 2.Q40954556
Increased gall-bladder prostanoid synthesis after bile-duct ligation in the rabbit is secondary to new enzyme formationQ41990441
Adenosine and ATP effects on isolated guinea pig gallbladderQ42254167
Bile duct ligation induced acute inflammation up-regulates cyclooxygenase-2 content and PGE2 release in guinea pig gallbladder smooth muscle cell culturesQ42477331
Cholecystokinin (CCK) down regulates PGE2 and PGI2 release in inflamed Guinea pig gallbladder smooth muscle cell culturesQ42481275
Role of cytosolic phospholipase A2 in cytokine-stimulated prostaglandin release by human gallbladder cellsQ42483635
Pharmacology and modulation of K(ATP) channels by protein kinase C and phosphatases in gallbladder smooth muscleQ42487538
ATP is released from guinea pig ureter epithelium on distensionQ42515631
Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bileQ42788280
Evidence for the expression of multiple uracil nucleotide-stimulated P2 receptors coupled to smooth muscle contraction in porcine isolated arteries.Q42940215
Cyclo-oxygenase-2 mediates P2Y receptor-induced reactive astrogliosisQ43189153
Cyclic AMP-mediated inhibition of gallbladder contractility: role of K+ channel activation and Ca2+ signalingQ43261600
ATP and UTP responses of cultured rat aortic smooth muscle cells revisited: dominance of P2Y2 receptorsQ43263169
Adenosine 5'-triphosphate release evoked by electrical nerve stimulation from the guinea-pig gallbladderQ43492009
Abnormalities of gallbladder muscle associated with acute inflammation in guinea pigsQ43669432
Constitutive expression and function of cyclooxygenase-2 in murine gastric musclesQ43976621
Induction of COX-2 and reactive gliosis by P2Y receptors in rat cortical astrocytes is dependent on ERK1/2 but independent of calcium signallingQ44242854
Influence of cholecystitis state on pharmacological response to cholecystokinin of isolated human gallbladder with gallstonesQ44457262
P433issue6
P304page(s)G1362-8
P577publication date2008-04-24
P1433published inAmerican Journal of Physiology - Gastrointestinal and Liver PhysiologyQ15765756
P1476titleATP induces guinea pig gallbladder smooth muscle excitability via the P2Y4 receptor and COX-1 activity
P478volume294

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cites work (P2860)
Q45347398Enhanced uridine adenosine tetraphosphate-induced contraction in renal artery from type 2 diabetic Goto-Kakizaki rats due to activated cyclooxygenase/thromboxane receptor axis
Q43441447Mechanisms underlying altered extracellular nucleotide-induced contractions in mesenteric arteries from rats in later-stage type 2 diabetes: effect of ANG II type 1 receptor antagonism
Q26861086Purinergic signalling in the gastrointestinal tract and related organs in health and disease
Q43102957Uridine adenosine tetraphosphate affects contractility of mouse aorta and decreases blood pressure in conscious rats and mice.