Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse

scientific article published on March 1957

Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1476-5381.1957.TB01354.X
P932PMC publication ID1509635
P698PubMed publication ID13413144
P5875ResearchGate publication ID10153625

P2093author name stringHALEY TJ
MCCORMICK WG
P2860cites workBehavioral and electroencephalographic effects of hallucinogenic drugs; changes in cats on intraventricular injection.Q51334116
A permanent cannula for intraventricular injections in cats.Q51348023
Effects of pre-administering various drugs on the acute pulmonary edema produced by blast injury and by the intravenous injection of epinephrine.Q53928882
Effects of intraventricular acetylcholine, cholinesterase, and related compounds in normal and catatonic cats.Q54034163
The absorption of histamine from the subarachnoid space of the dogQ73207542
Centrally mediated effects of cardiac drugs: strophanthin-K, quinidine and procaine amideQ73716084
Comparison of strophanthin-K and tryptamine-strophanthidin after intraventricular injection in unanesthetized dogsQ73803011
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
P304page(s)12-15
P577publication date1957-03-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titlePharmacological effects produced by intracerebral injection of drugs in the conscious mouse
P478volume12

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cites work (P2860)
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Q44293185Buspirone-induced antinociception is mediated by L-type calcium channels and calcium/caffeine-sensitive pools in mice
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Q28361058Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation
Q37091405Central administration of angiotensin IV rapidly enhances novel object recognition among mice
Q34807215Central amygdala glucocorticoid receptor action promotes fear-associated CRH activation and conditioning
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Q44944176Central and peripheral visceral effects of bombesin
Q41782285Central antinociception induced by mu-opioid receptor agonist morphine, but not delta- or kappa-, is mediated by cannabinoid CB1 receptor
Q48729296Central corticotropin-releasing factor and benzodiazepine receptor systems are involved in the social isolation stress-induced decrease in ethanol sleep in mice
Q48835658Central effects of 5-hydroxytryptamine and noradrenaline on body temperature and oxygen consumption in infant rats
Q42075715Central injection of nitric oxide synthase inhibitors increases peripheral interleukin-6 and serum amyloid A: involvement of adrenaline from adrenal medulla
Q35044444Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test
Q67376424Central neurotoxicity of apamin, crotamin, phospholipase A and α-amanitin
Q66966268Centrally and peripherally mediated inhibition of intestinal motility by opioids
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Q44351419Characterization of mechanical withdrawal responses and effects of mu-, delta- and kappa-opioid agonists in normal and mu-opioid receptor knockout mice
Q48827215Characterization of temporal expressions of FOXO and pFOXO proteins in the hippocampus by kainic acid in mice: involvement of NMDA and non-NMDA receptors
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Q44308553Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence
Q49843389Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction
Q41058585Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice
Q73670985Effect of 7-nitroindazole on tolerance to morphine, U-50,488H and [D-Pen2, D-Pen5] enkephalin in mice
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Q40094581Effect of benzodiazepines on central serotonergic neuron systems
Q48560843Effect of chronic administration of [D-Pen2, D-Pen5] enkephalin on the activity of nitric oxide synthase in brain regions and spinal cord of mice
Q44338130Effect of chronic ethanol treatment on μ-opioid receptor function, interacting proteins and morphine-induced place preference
Q58133827Effect of histamine receptors agonists or antagonists administered intracerebroventricularly and intrathecally on the blood glucose level in immobilization stress model
Q67462840Effect of intracerebroventricular 5,6-dihydroxytryptamine on blood pressure of spontaneously hypertensive rats
Q71562892Effect of nitric oxide synthase inhibition on tolerance to the analgesic action of D-Pen2, D-Pen5 enkephalin and morphine in the mouse
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Q48254264Effect of pretreatment with pertussis toxin on the development of physical dependence on morphine
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Q44347403Effect of supraspinal antisense oligodeoxynucleotide treatment on delta-opioid receptor mRNA levels in mice
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Q48420760Effects of centrally administered H2 antagonists in the behavioral despair test
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Q36588384Effects of elevated calcium and calcium antagonists on 6,7-benzomorphan-induced analgesia
Q41203727Effects of erythropoietin on memory deficits and brain oxidative stress in the mouse models of dementia
Q28363252Effects of ganglion blocking agents on nicotine extensor convulsions and lethality in mice
Q44345442Effects of ibogaine and noribogaine on the antinociceptive action of mu-, delta- and kappa-opioid receptor agonists in mice
Q44345449Effects of ibogaine on the development of tolerance to antinociceptive action of mu-, delta- and kappa-opioid receptor agonists in mice
Q72828370Effects of intrathecal or intracerebroventricular pretreatment with pertussis toxin on antinociception induced by beta-endorphin or morphine administered intracerebroventricularly in mice
Q44344579Effects of morphine-3-glucuronide on the antinociceptive activity of peptide and nonpeptide opioid receptor agonists in mice
Q44345005Effects of multiple intracerebroventricular injections of [D-Pen2,D-Pen5]enkephalin and [D-Ala2,Glu4]deltorphin II on tolerance to their analgesic action and on brain delta-opioid receptors
Q93136416Effects of resveratrol and oxyresveratrol on hippocampal cell death induced by kainic acid
Q44346259Effects of some 7-arylidene and 7-heteroarylidene morphinan-6-ones on the antinociceptive activity of [D-Pen2, D-Pen5]enkephalin and [D-Ala2, Glu4]deltorphin II and on multiple opioid receptors
Q72913155Effects of ß-Endorphin on body temperature in mice at different ambient temperatures
Q35177657Enhancement of a nociceptive reaction by opioid antagonists in mice
Q44343222Enhancement of blood-brain barrier permeability to sodium fluorescein by stimulation of mu opioid receptors in mice
Q39122695Enhancement of ethanol-induced withdrawal convulsions by blockade of 5-hydroxytryptamine receptors
Q41489647Evidence for a cholinergic role in haloperidol-induced catalepsy
Q71611832Evidence for central histaminergic mechanism in foot shock aggression
Q77152158Evidence for hypernociception induction following histamine H1 receptor activation in rodents
Q35169472Fisetin exerts antihyperalgesic effect in a mouse model of neuropathic pain: engagement of spinal serotonergic system
Q48726235Flumazenil but not FG7142 reverses the decrease in pentobarbital sleep caused by activation of central noradrenergic systems in mice
Q51550104Flumazenil reverses the decrease in the hypnotic activity of pentobarbital by social isolation stress: are endogenous benzodiazepine receptor ligands involved?
Q36304967Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: evidence for opposing NO actions on morphine analgesia and tolerance
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Q48813752Hyperactivity of central noradrenergic and CRF systems is involved in social isolation-induced decrease in pentobarbital sleep
Q34023260Hyperbaric oxygen treatment induces a 2-phase antinociceptive response of unusually long duration in mice
Q35069667Hypothalamic GPR40 signaling activated by free long chain fatty acids suppresses CFA-induced inflammatory chronic pain
Q24301144Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity
Q37290396Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine
Q28379239Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release
Q48319054Identification of the receptor subtype involved in the analgesic effect of neurotensin
Q28830911In Vivo Characterization of ARN14140, a Memantine/Galantamine-Based Multi-Target Compound for Alzheimer's Disease
Q47319838In vivo and ex vivo analyses of amyloid toxicity in the Tc1 mouse model of Down syndrome
Q36952288In vivo characterization of (-)(-)MCL-144 and (+)(-)MCL-193: isomeric, bivalent ligands with mu/kappa agonist properties
Q44538194In vivo stimulation of sympathetic nervous system modulates osteoblastic activity in mouse calvaria
Q38362785Inactivation of Gi proteins induces an antidepressant-like effect in the mouse forced-swimming test
Q34062512Increased methylation of the MOR gene proximal promoter in primary sensory neurons plays a crucial role in the decreased analgesic effect of opioids in neuropathic pain
Q43169496Induced association of mu opioid (MOP) and type 2 cholecystokinin (CCK2) receptors by novel bivalent ligands
Q39615615Influence of catecholamines on dexamphetamine-induced changes in locomotor activity
Q51381491Influence of different histamine receptor agonists and antagonists on apomorphine-induced licking behavior in rat.
Q43084786Influence of potassium channel modulators on cognitive processes in mice.
Q36783997Inhibition of MAO-A and stimulation of behavioural activities in mice by the inactive prodrug form of the anti-influenza agent oseltamivir
Q37598746Inhibition of acute inflammation in the periphery by central action of salicylates
Q71673878Inhibitory effects of salmon calcitonin on the tail-biting and scratching behavior induced by substance P and three excitatory amino acids
Q51312235Injection of drugs into the cerebral ventricle of sheep
Q67556039Intensification of amphetamine-induced excitation by methysergide, a serotonergic receptor blocker
Q51526580Interactions of cocaine with morphine, U-50,488H and [D-Pen2, D-Pen5]enkaphalin.
Q36366085Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice
Q51409146Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits.
Q85045686Intracerebroventricular administration of apelin-13 inhibits distal colonic transit in mice
Q53542960Intracerebroventricular ginsenosides are antinociceptive in proinflammatory cytokine-induced pain behaviors of mice.
Q46366822Intracerebroventricular guanine-based purines protect against seizures induced by quinolinic acid in mice
Q35754450Intracerebroventricular injection of anti-Fas activates the hypothalamus-pituitary-adrenal axis and induces peripheral interleukin-6 and serum amyloid A in mice: comparison with other ligands of the tumor necrosis factor/nerve growth factor receptor
Q40546664Intracerebroventricular interleukin-6, macrophage inflammatory protein-1β and IL-18: pyrogenic and PGE2-mediated?
Q67276978Intracerebroventricular treatment of mice with pertussis toxin induces hyperalgesia and enhances 3H-nitrendipine binding to synaptic membranes: similarity with morphine tolerance
Q42563153Investigation into atropine-induced antinociception
Q46090398Involvement of PLC-beta3 in the effect of morphine on memory retrieval in passive avoidance task
Q34633464Involvement of a NO-cyclic GMP-PKG signaling pathway in nitrous oxide-induced antinociception in mice
Q69370395Involvement of central histaminergic and cholinergic systems in the morphine-induced increase in blood-brain barrier permeability to sodium fluorescein in mice
Q44342915Involvement of central μ-opioid system in the scratching behavior in mice, and the suppression of it by the activation of κ-opioid system
Q38342129Involvement of kappa opioid receptors in the formalin-induced inhibition of analgesic tolerance to morphine via suppression of conventional protein kinase C activation
Q70061981Involvement of norepinephrine neurons in the hypothermia induced by intracerebroventricular administration of 6-hydroxydopamine in mice, evidenced by antidepressants
Q43509803Involvement of potassium channels in amitriptyline and clomipramine analgesia.
Q48678620Involvement of α(2)-adrenergic receptor in the regulation of the blood glucose level induced by immobilization stress
Q91635460Isorhynchophylline Exerts Antinociceptive Effects on Behavioral Hyperalgesia and Allodynia in a Mouse Model of Neuropathic Pain: Evidence of a 5-HT1A Receptor-Mediated Mechanism
Q36163631Kappa Opioid Receptor-Mediated Disruption of Novel Object Recognition: Relevance for Psychostimulant Treatment
Q43503068Kappa opioid agonists as targets for pharmacotherapies in cocaine abuse
Q42083765L-arginine exerts a dual role in nociceptive processing in the brain: involvement of the kyotorphin-Met-enkephalin pathway and NO-cyclic GMP pathway
Q49021124L-type voltage-dependent calcium channels facilitate acetylation of histone H3 through PKCγ phosphorylation in mice with methamphetamine-induced place preference
Q41868169Leucine-enkephalin and methionine-enkephalin produce opposing effects on plasma corticosterone levels in ether-stressed mice
Q37010754Ligands that interact with putative MOR-mGluR5 heteromer in mice with inflammatory pain produce potent antinociception.
Q72637720Liver damage from narcotics in mice
Q28363126Long-lasting antinociceptive effects of a novel dynorphin analogue, Tyr-D-Ala-Phe-Leu-Arg psi (CH(2)NH) Arg-NH(2), in mice
Q38312898Loss of muscarinic antinociception by antisense inhibition of M(1) receptors
Q47740126Lysophosphatidic acid induces anxiety-like behavior via its receptors in mice
Q28210294M1 receptor activation is a requirement for arecoline analgesia
Q35870857MDL 27,531 selectively reverses strychnine-induced seizures in mice
Q44331107Maintenance of acute morphine tolerance in mice by selective blockage of κ opioid receptors with norbinaltorphimine
Q72385476Mechanism of analgesic action of mesaconitine. I. Relationship between analgesic effect and central monoamines or opiate receptors
Q72858994Mechanism of chlorpromazine action on plasma glucose and cyclic amp levels
Q48505810Mediation of the hypoglycaemic effect of 5-hydroxytryptophan by a central nervous system action
Q48874402Meloxicam-loaded nanocapsules as an alternative to improve memory decline in an Alzheimer's disease model in mice: involvement of Na(+), K(+)-ATPase
Q88683310Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A
Q42794550Memory restorative role of statins in experimental dementia: an evidence of their cholesterol dependent and independent actions
Q28207609Menthol: a natural analgesic compound
Q49082665Metabolism of the ethanolamine phosphoglycerides of mouse brain myelin and microsomes
Q41572234Metergoline elevates or reduces nociceptive thresholds in mice depending on test method and route of administration
Q34187516Methadone antinociception is dependent on peripheral opioid receptors
Q28362087Methylamine and benzylamine induced hypophagia in mice: modulation by semicarbazide-sensitive benzylamine oxidase inhibitors and aODN towards Kv1.1 channels
Q42275058Methylamine, but not ammonia, is hypophagic in mouse by interaction with brain Kv1.6 channel subtype
Q34538336Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.
Q39176305Modification by monoamine oxidase inhibitors of the analgesic, hypothermic and toxic actions of morphine and pethidine in mice
Q71823029Modification of the anti-nociceptive activity of morphine by centrally administered ouabain and dopamine
Q48010033Modulation of PKA, PKC, CAMKII, ERK 1/2 pathways is involved in the acute antidepressant-like effect of (octylseleno)-xylofuranoside (OSX) in mice
Q41992250Modulation of opioid antinociception by CCK at the supraspinal level: evidence of regulatory mechanisms between CCK and enkephalin systems in the control of pain
Q44164255Molecular chaperone heat shock protein 70 participates in the labile phase of the development of behavioural sensitization induced by a single morphine exposure in mice.
Q70171593Morphine exacerbates anaphylactic shock in mice by stimulating central opiate receptors
Q48407252Morphine suppression of ethanol withdrawal in mice
Q43867289Mouse light/dark box test reveals anxiogenic-like effects by activation of histamine H1 receptors
Q72490121Multi-dimensional analyses of behavior in mice treated with α-endorphin
Q39995189Multiple emulsions, a suitable vehicle to provide sustained release of cancer chemotherapeutic agents
Q44966063NDP-MSH inhibits neutrophil migration through nicotinic and adrenergic receptors in experimental peritonitis
Q35749650Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia
Q70109080Naloxone prevents the analgesic action of alpha-MSH in mice
Q48680800Naloxone reverses the inhibitory effects of dynorphin A on motor activity in the mouse
Q67490516Naloxone-induced analgesia in diabetic mice
Q43836491Narcotic agonists and antagonists as models for potential antidepressant drugs
Q69836985Narcotic antagonism of seizures induced by a dopamine-derived tetrahydroisoquinoline alkaloid
Q64068504Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice
Q47267653Neuroprotective effects of the gliopeptide ODN in an in vivo model of Parkinson's disease
Q28257563Neurotoicity of apamin and MCD peptide upon central application
Q72660879Neurotoxins, protease inhibitors and histamine releasers in the venom of the Indian red scorpion (Buthus tamulus): Isolation and partial characterization
Q28343438Nociceptin/orphanin FQ and nocistatin on learning and memory impairment induced by scopolamine in mice
Q48715462Nocistatin and nociceptin modulate c-Fos expression in the mice thalamus
Q34525251Nonpeptide small molecule agonist and antagonist original leads for neuropeptide FF1 and FF2 receptors
Q43558284Novel inhibitors of enkephalin-degrading enzymes. I: Inhibitors of enkephalinase by penicillins
Q28340574Novel inhibitors of enkephalin-degrading enzymes. II: N5'-substituted-4-thioxohydantoic acids as aminopeptidase inhibitors
Q35940344Novel opioid cyclic tetrapeptides: Trp isomers of CJ-15,208 exhibit distinct opioid receptor agonism and short-acting κ opioid receptor antagonism
Q34247017Opiate antagonistic properties of an octapeptide somatostatin analog
Q43307682Opiate-like action of methionine-enkephalin in inhibiting morphine abstinence syndrome
Q36225640Opioid activity of spinally selective analogues of N-naphthoyl-β-naltrexamine in HEK-293 cells and mice
Q34244966Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series
Q35085111Oxidation-sensitive nociception involved in endometriosis-associated pain
Q50629865Pain regulation of endokinin A/B or endokinin C/D on chimeric peptide MCRT in mice.
Q51311690Passage of circulating adrenaline into perfused cerebral ventricles and subarachnoidal space.
Q28564943Peptides derived from the prohormone proNPQ/spexin are potent central modulators of cardiovascular and renal function and nociception
Q42261074Peripheral toxicity of hemicholinium-3 in mice
Q44333852Pharmacological characterization of [D-Ala2,Leu5,Ser6]enkephalin (DALES): antinociceptive actions at the δnon-complexed-opioid receptor
Q72565508Pharmacological characterization of the receptors involved in the apomorphine-induced polyphasic modifications of locomotor activity in mice
Q36610342Pharmacological effects of 3-iodothyronamine (T1AM) in mice include facilitation of memory acquisition and retention and reduction of pain threshold
Q36429323Pharmacological inhibition of TLR4-NOX4 signal protects against neuronal death in transient focal ischemia
Q44351544Pharmacological interaction of the calcium channel blockers verapamil and flunarizine with the opioid system
Q40017952Pharmacological properties of centrally administered ouabain and their modification by other drugs
Q43001927Pharmacological properties of centrally-administered agents which interfere with neurotransmitter function: a comparison with the central depressant effects of ouabain
Q42023907Pharmacological properties of pempidine (1:2:2:6:6-pentamethylpiperidine), a new ganglion-blocking compound
Q51149383Pharmacological significances of peptidase and proteinase in the brain. 4. Effect of bradykinin on the central nervous system and role of the enzyme inactivating bradykinin in mouse brain
Q46399968Pituitary adenylate cyclase-activating polypeptide inhibits food intake in mice through activation of the hypothalamic melanocortin system.
Q69503979Possible involvement of a dopaminergic pathway in the depressant effects of ouabain on the central nervous system
Q72040797Possible involvement of nitric oxide in quinolinic acid-induced convulsion in mice
Q48257933Possible neuronal mechanisms involved in neurotensin-induced catalepsy in mice
Q44344808Potentiation of delta 9-tetrahydrocannabinol-induced analgesia by morphine in mice: involvement of mu- and kappa-opioid receptors
Q44182452Potentiation of morphine analgesia by BQ123, an endothelin antagonist
Q28591665Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system
Q48922339Potentiation of phenobarbital-induced anticonvulsant activity by pipecolic acid
Q24811385Pre-injury administration of morphine prevents development of neuropathic hyperalgesia through activation of descending monoaminergic mechanisms in the spinal cord in mice
Q36863382Preclinical characterization of MDL 27,192 as a potential broad spectrum anticonvulsant agent with neuroprotective properties
Q52025435Pro-cognitive activity induced in the rat by low doses of R-(+)-hyoscyamine.
Q46851153Protective effect of ((4-tert-butylcyclohexylidene) methyl) (4-methoxystyryl) sulfide, a novel unsymmetrical divinyl sulfide, on an oxidative stress model induced by sodium nitroprusside in mouse brain: involvement of glutathione peroxidase activity
Q42585845Putrescine catabolism in mammalian brain
Q48819905Rat supraoptic neurones: nucleolar changes in response to posterior pituitary extracts
Q64057527Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer's disease
Q44336278Redoubling the ring size of an endomorphin-2 analog transforms a centrally acting mu-opioid receptor agonist into a pure peripheral analgesic
Q72561684Reduction in ATP-sensitive potassium channel-mediated antinociception in diabetic mice
Q42883618Regulation of ryanodine receptors by dopamine D1 receptors during methamphetamine‐induced place conditioning
Q37705976Resveratrol-induced antinociception is involved in calcium channels and calcium/caffeine-sensitive pools
Q44330314Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice
Q48372847Reversal of the reserpine-induced ptosis by L-threo-3,4-dihydroxy-phenylserine (L-threo-DOPS), a (-)-norepinephrine precursor, and its potentiation by imipramine or nialamide
Q43178535Reversal of tolerance to the antitransit effects of morphine during acute intestinal inflammation in mice
Q36133099Reversible antisense inhibition of Shaker-like Kv1.1 potassium channel expression impairs associative memory in mouse and rat
Q44099995Rodent antinociception following acute treatment with different histamine receptor agonists and antagonists
Q54027566Role of ATP-sensitive K+ channels in antinociception induced by R-PIA, an adenosine A1 receptor agonist.
Q71614613Role of L-type calcium channels on yohimbine-precipitated clonidine withdrawal in vivo and in vitro
Q71338905Role of brain catecholamines and 5-hydroxytryptamine in morphine induced temperature changes in normal and tolerant rats and mice
Q40740621Role of central ATP-sensitive potassium channels in the hyperthermic effect of morphine in mice
Q35048685Role of descending noradrenergic system and spinal alpha2-adrenergic receptors in the effects of gabapentin on thermal and mechanical nociception after partial nerve injury in the mouse
Q42115852Role of histamine in rodent antinociception
Q43662399Role of hypothalamic-pituitary axis in morphine-induced alteration in thymic cell distribution using mu-opioid receptor knockout mice
Q41847231Role of muscarinic receptor subtypes in central antinociception
Q73964401Role of nitric oxide in diabetes-induced attenuation of antinociceptive effect of morphine in mice
Q44472575Role of platelet activating factor in triazolobenzodiazepines-induced retrograde amnesia
Q43189745Role of potassium channels in the antinociception induced by agonists of alpha2-adrenoceptors
Q31925777Selective inhibition of amine oxidases differently potentiate the hypophagic effect of benzylamine in mice
Q33911524Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after i.c.v. administration in mice.
Q43643813Selegiline reverses aβ₂₅₋₃₅-induced cognitive deficit in male mice.
Q42732287Selenofuranoside Ameliorates Memory Loss in Alzheimer-Like Sporadic Dementia: AChE Activity, Oxidative Stress, and Inflammation Involvement
Q48544854Sensitization of ethanol-induced place preference as a result of up-regulation of type 1 inositol 1,4,5-trisphosphate receptors in mouse nucleus accumbens
Q36274644Sex-specific mediation of opioid-induced hyperalgesia by the melanocortin-1 receptor
Q49137365Short-term behavioral effects of posterior pituitary peptides in mice
Q71364200Short-term manganese pretreatment partially protects against 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
Q48772612Sodium transport through the cerebral sodium-glucose transporter exacerbates neuron damage during cerebral ischaemia
Q41349220Some actions of delta-1 tetrahydrocannabinol and cannabidiol at cholinergic junctions
Q79222521Some biological properties of two fluoro-derivatives of tryptamine
Q39158674Some observations on the mechanism of benzodiazepine-barbiturate interactions in the mouse
Q41863608Some shortcomings of direct intraventricular injection in mice
Q54095325Spasmolytic and cholinergic blocking properties and toxicity of levomepate, I-tropine α-methyltropate
Q44334306Spinal GABA receptors mediate brain delta opioid analgesia in Swiss Webster mice
Q35100897Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury
Q37396218Steady-state level and turnover rate of the tripeptide Tyr-Gly-Gly as indexes of striatal enkephalin release in vivo and their reduction during pentobarbital anesthesia
Q48961230Stereoselective increase in cholinergic transmission by R-(+)-hyoscyamine
Q42196788Stereotaxic implantation of cannulae for subsequent drug administration into the third ventricles of conscious mice [proceedings]
Q48596436Streptozotocin Induces Mild Cognitive Impairment at Appropriate Doses in Mice as Determined by Long-Term Potentiation and the Morris Water Maze.
Q71153084Studies on the central effects of bulbocapnine
Q66692352Studies on the effects of histaminergic agents on seizure susceptibility in mice
Q39996018Study of the mechanisms of action of desipramine and chlorpromazine in reversing reserpine-induced hypothermia in mice.
Q34793265Subgroups among mu-opioid receptor agonists distinguished by ATP-sensitive K+ channel-acting drugs
Q67767964Suppression of ethanol withdrawal by dopamine
Q35001766Supraspinal administration of opioids with selectivity for mu-, delta- and kappa-opioid receptors produces analgesia in amphibians
Q44345360Supraspinal delta 1-opioid receptor-mediated antinociceptive properties of (-)-TAN-67 in diabetic mice
Q42083576Supraspinal-selective TRPV1 desensitization induced by intracerebroventricular treatment with resiniferatoxin.
Q33830017Supraspinally-administered agmatine attenuates the development of oral fentanyl self-administration
Q41434217Synaptosomal accumulation of intracerebral injected amino acids
Q50971812Synergistic effect of docosahexaenoic acid on anticonvulsant activity of valproic acid and lamotrigine in animal seizure models.
Q46457647Synthesis and antinociceptive effects of endomorphin-1 analogs with C-terminal linked by oligoarginine
Q35756505Synthesis and pharmacology of halogenated δ-opioid-selective [d-Ala(2)]deltorphin II peptide analogues
Q89507507Synthesis, Molecular Docking, and Preliminary Evaluation of 2-(1,2,3-Triazoyl)benzaldehydes As Multifunctional Agents for the Treatment of Alzheimer's Disease
Q44182810Targeted inactivation of the neurotensin type 1 receptor reveals its role in body temperature control and feeding behavior but not in analgesia
Q51204611Temperature changes produced by the injection of catecholamines and 5-hydroxytryptamine into the cerebral ventricles of the conscious mouse
Q39371102Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia
Q38262682The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders
Q44433754The Phospholipase C-IP3 Pathway is Involved in Muscarinic Antinociception
Q41987929The activation of supraspinal GPR40/FFA1 receptor signalling regulates the descending pain control system
Q34504856The acute antinociceptive effect of HBO₂ is mediated by a NO-cyclic GMP-PKG-KATP channel pathway in mice
Q50947616The analgesic effect of trans-resveratrol is regulated by calcium channels in the hippocampus of mice.
Q41603023The anti-amnesic and neuroprotective effects of donepezil against amyloid beta25-35 peptide-induced toxicity in mice involve an interaction with the sigma1 receptor
Q59357319The antinociceptive effect of fluvoxamine
Q37190334The antinociceptive effects of ferulic acid on neuropathic pain: involvement of descending monoaminergic system and opioid receptors
Q35226846The assay of anti-pyretic drugs in mice, using intracerebral injection of pyretogenins
Q51750311The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.
Q34611911The central analgesia induced by antimigraine drugs is independent from Gi proteins: superiority of a fixed combination of indomethacin, prochlorperazine and caffeine, compared to sumatriptan, in an in vivo model
Q30489474The comparative pharmacology of some psychotropic drugs.
Q43822150The effect of 6-hydroxydopamine on the antinociceptive action of morphine
Q71572177The effect of 6-hydroxydopamine on the antinociceptive action of oxotremorine
Q69582011The effect of ?-amanitin on passive and active avoidance acquisition in mice
Q44335803The effect of chronic treatment with naltrindole, a selective delta-opioid antagonist, on mu-opioid receptor-mediated antinociception in diabetic mice
Q41726994The effect of intracerebroventricular administration of methionine-enkephalin on the stress-induced secretion of corticosterone in mice
Q39709879The effect of propranolol phentolamine and pimozide on drug-induced anorexia in the mouse
Q44342255The effects of dopamine D1 and D2 receptor antagonists on the rewarding effects of delta 1 and delta 2 opioid receptor agonists in mice
Q41357088The effects of intracerebroventricularly administered noradnamine and other sympathomimetic amines upon leptazol convulsions in mice
Q71275512The effects of intraventricular 6-hydroxydopamine and 5,6-dihydroxytryptamine on morphine induced locomotor stimulation
Q89440606The efficacy of intracerebroventricular idursulfase-beta enzyme replacement therapy in mucopolysaccharidosis II murine model: heparan sulfate in cerebrospinal fluid as a clinical biomarker of neuropathology
Q37152489The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment
Q50432587The impact of scopolamine pretreatment on 3-iodothyronamine (T1AM) effects on memory and pain in mice
Q28379396The inhibitory effects of alpha(2)-adrenoceptor agonists on gastrointestinal transit during croton oil-induced intestinal inflammation
Q41363104The interactions of noradnamine and imipramine-like antidepressant drugs
Q51230311The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
Q51220779The iron content of the brain of rats with choreiform movements
Q44345741The mu-opioid receptor is necessary for [D-Pen2,D-Pen5]enkephalin-induced analgesia
Q41899918The nonpeptide neurotensin antagonist, SR 48692, used as a tool to reveal putative neurotensin receptor subtypes
Q42702715The noradrenaline precursor L-threo-3,4-dihydroxyphenylserine exhibits antinociceptive activity via central alpha-adrenoceptors in the mouse
Q89464718The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs
Q44808718The reduction of food intake induced in mice by benzylamine and its derivatives
Q41355644The reversal of the central effects of noradrenaline by antidepressant drugs in mice
Q51426529The role of potassium channels in antihistamine analgesia.
Q34601489The synthetic TRH analogue taltirelin exerts modality-specific antinociceptive effects via distinct descending monoaminergic systems
Q48681606Thyrotropin-releasing hormone (TRH) improves survival in anaphylactic shock: A central effect mediated by the sympatho-adrenomedullary β-adrenoceptive system
Q48244715Tiagabine antinociception in rodents depends on GABA(B) receptor activation: parallel antinociception testing and medial thalamus GABA microdialysis
Q36770675Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS.
Q36887197Unexpected opioid activity profiles of analogues of the novel peptide kappa opioid receptor ligand CJ-15,208
Q54348613Unexpected potentiation by discriminant benzamide derivatives of stereotyped behaviours elicited by dopamine agonists in mice.
Q74072554Up-regulation of brain N-methyl-D-aspartate receptors following multiple intracerebroventricular injections of [D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin II in mice
Q45130083Utility of an elevated plus-maze for the evaluation of memory in mice: effects of nootropics, scopolamine and electroconvulsive shock
Q42565331Vasopressin and stress-induced antinociception in the mouse
Q48421496Ventricular injection of nerve growth factor increases dopamine content in the striata of MPTP-treated mice
Q35544270Visceral hyperalgesia induced by forebrain-specific suppression of native Kv7/KCNQ/M-current in mice
Q35037821beta-Endorphin: cross tolerance to and cross physical dependence on morphine
Q34394408beta-endorphin is a potent analgesic agent
Q33829223cAMP/PKA-CREB-BDNF signaling pathway in hippocampus mediates cyclooxygenase 2-induced learning/memory deficits of rats subjected to chronic unpredictable mild stress
Q44348820mu-Opioid receptor-knockout mice: the role of mu-opioid receptor in gastrointestinal transit
Q49125329α-Adrenergic agents. 3. Behavioral effects of 2-aminotetralins
Q44334963δ-Opioid receptor agonist SNC80 induces central antinociception mediated by Ca2+ -activated Cl- channels
Q44333497κ-Opioid receptor agonists improve pirenzepine-induced disturbance of spontaneous alternation performance in the mouse