Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein

scientific article published on 27 June 2017

Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.18698
P932PMC publication ID5620184
P698PubMed publication ID28978044

P50authorBeatrice Schuler-ThurnerQ92348405
Matteo RamazzottiQ38328011
Inge Marie SvaneQ39271516
Duccio CavalieriQ42698095
Irene StefaniniQ56855044
Stefanie GrossQ56856922
P2093author name stringSonja I Buschow
Carl G Figdor
Jiannis Ragoussis
Harm Westdorp
Gerold Schuler
Dilair Baban
Luca Beltrame
Eva Ellebaek
Stanleyson V Hato
Jonathan M Austyn
Nikolaus Romani
Van Anh Nguyen
Lucie M Heinzerling
Georg Weinlich
I Jolanda M De Vries
Inge M J Reinieren-Beeren
P2860cites workWild-type and modified gp100 peptide-pulsed dendritic cell vaccination of advanced melanoma patients can lead to long-term clinical responses independent of the peptide usedQ58619928
Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma PatientsQ58619940
Immunomonitoring Tumor-Specific T Cells in Delayed-Type Hypersensitivity Skin Biopsies After Dendritic Cell Vaccination Correlates With Clinical OutcomeQ58620035
Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trialQ60634928
S100-Beta, melanoma-inhibiting activity, and lactate dehydrogenase discriminate progressive from nonprogressive American Joint Committee on Cancer stage IV melanomaQ73181527
Mage-3 and influenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocyte-derived dendritic cellsQ74280070
Inverse association between Raf Kinase Inhibitory Protein and signal transducers and activators of transcription 3 expression in gastric adenocarcinoma patients: implications for clinical outcomeQ81286559
Combined Nivolumab and Ipilimumab or Monotherapy in Untreated MelanomaQ86229575
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genesQ24534395
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activationQ24548297
Significance analysis of microarrays applied to the ionizing radiation responseQ24606608
Oncolytic virus therapy: A new era of cancer treatment at dawnQ26739714
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standardsQ26744395
Paving the Road to Tumor Development and Spreading: Myeloid-Derived Suppressor Cells are Ruling the FateQ26777205
Melanoma: From Incurable Beast to a Curable Bet. The Success of ImmunotherapyQ26798404
CTLA-4 and PD-1/PD-L1 blockade: new immunotherapeutic modalities with durable clinical benefit in melanoma patientsQ27692628
Improving cancer immunotherapy by targeting the STATe of MDSCsQ28066797
Signal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapyQ28080262
Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIPQ28144497
Visualisation of BioPAX Networks using BioLayout Express (3D)Q28649340
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesQ29547229
Final version of 2009 AJCC melanoma staging and classificationQ29614803
lumi: a pipeline for processing Illumina microarrayQ29614924
STRING v10: protein-protein interaction networks, integrated over the tree of lifeQ29615545
Myeloid-derived suppressor cells are associated with disease progression and decreased overall survival in advanced-stage melanoma patientsQ34250873
Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapyQ34522172
Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanomaQ35078852
Assessment of EGFR mutations in circulating tumor cell preparations from NSCLC patients by next generation sequencing: toward a real-time liquid biopsy for treatmentQ35227986
Gene-expression profiling in vaccine therapy and immunotherapy for cancerQ36138329
Reduction of RKIP expression promotes nasopharyngeal carcinoma invasion and metastasis by activating Stat3 signalingQ36140818
Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanomaQ36375683
The tumour microenvironment and implications for cancer immunotherapyQ36521830
MDSC-decreasing chemotherapy increases the efficacy of cytokine-induced killer cell immunotherapy in metastatic renal cell carcinoma and pancreatic cancerQ36782579
RKIP contributes to IFN-γ synthesis by CD8+ T cells after serial TCR triggering in systemic inflammatory response syndromeQ36986264
Dendritic cell vaccination and immune monitoring.Q37212802
Mutation landscape in melanoma patients clinical implications of heterogeneity of BRAF mutationsQ37352562
integrOmics: an R package to unravel relationships between two omics datasetsQ37432352
Raf kinase inhibitor RKIP inhibits MDA-9/syntenin-mediated metastasis in melanomaQ37611006
Molecular signatures of antibody responses derived from a systems biology study of five human vaccinesQ37625332
Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapyQ37778702
Profile of ipilimumab and its role in the treatment of metastatic melanomaQ37977920
RKIP: much more than Raf kinase inhibitory proteinQ38077517
Circulating tumour cells and circulating free nucleic acid as prognostic and predictive biomarkers in colorectal cancerQ38173798
Signaling pathways involved in MDSC regulationQ38204175
Interactions of RKIP with inflammatory signaling pathwaysQ38322294
Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potentialQ38414485
Dendritic Cell-Based Immunotherapy: State of the Art and Beyond.Q38809786
Elevated chronic inflammatory factors and myeloid-derived suppressor cells indicate poor prognosis in advanced melanoma patientsQ38944200
Myeloid-derived suppressor cells predict survival of patients with advanced melanoma: comparison with regulatory T cells and NY-ESO-1- or melan-A-specific T cellsQ39584588
Baseline Biomarkers for Outcome of Melanoma Patients Treated with PembrolizumabQ40506025
Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines.Q40529472
Increases in Absolute Lymphocytes and Circulating CD4+ and CD8+ T Cells Are Associated with Positive Clinical Outcome of Melanoma Patients Treated with IpilimumabQ40758666
Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responsesQ40802250
Myeloid Cells and Related Chronic Inflammatory Factors as Novel Predictive Markers in Melanoma Treatment with IpilimumabQ41469907
Predictive immune markers in advanced melanoma patients treated with ipilimumabQ42427603
Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trialQ43080246
International trends in the incidence of malignant melanoma 1953-2008--are recent generations at higher or lower risk?Q43604521
Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancerQ44670943
Utility of the housekeeping genes 18S rRNA, beta-actin and glyceraldehyde-3-phosphate-dehydrogenase for normalization in real-time quantitative reverse transcriptase-polymerase chain reaction analysis of gene expression in human T lymphocytesQ44925185
Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccinationQ46885041
Myeloid-derived suppressor cells impair the quality of dendritic cell vaccines.Q50669894
Predictive gene signature in MAGE-A3 antigen-specific cancer immunotherapy.Q50954469
EGFR mutational genotyping of liquid based cytology samples obtained via fine needle aspiration (FNA) at endobronchial ultrasound of non-small cell lung cancer (NSCLC).Q51694711
The role of Raf kinase inhibitor protein in rheumatoid fibroblast-like synoviocytes invasiveness and cytokine and matrix metalloproteinase expression.Q54591208
Validation of housekeeping genes for normalizing RNA expression in real-time PCR.Q54708147
Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma PatientsQ56637518
Clinical application of circulating tumor cells in breast cancerQ57129057
Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell-Based Vaccination in Metastatic MelanomaQ58619897
P433issue40
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
metastatic melanomaQ18975855
P304page(s)67439-67456
P577publication date2017-06-27
P1433published inOncotargetQ1573155
P1476titleSurvival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein
P478volume8

Reverse relations

cites work (P2860)
Q89978064Blood Eosinophilia is an on-Treatment Biomarker in Patients with Solid Tumors Undergoing Dendritic Cell Vaccination with Autologous Tumor-RNA
Q93018018Oncolytic virotherapy enhances the efficacy of a cancer vaccine by modulating the tumor microenvironment
Q58704356RKIP: A Key Regulator in Tumor Metastasis Initiation and Resistance to Apoptosis: Therapeutic Targeting and Impact

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