review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Giorgio Fedele | Q56810661 |
P2093 | author name string | Nela Klimova | |
Irena Adkins | |||
Peter Sebo | |||
Ilaria Schiavoni | |||
P2860 | cites work | Bordetella pertussis Infection in 2-Month-Old Infants Promotes Type 1 T Cell Responses | Q61766641 |
Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones | Q70054755 | ||
Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two steps | Q21131558 | ||
Circulating Th17, Th22, and Th1 cells are increased in psoriasis | Q24629315 | ||
RTX proteins: a highly diverse family secreted by a common mechanism | Q24630254 | ||
The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18) | Q24675699 | ||
Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores | Q27346834 | ||
Pertussis toxin and the adenylate cyclase toxin from Bordetella pertussis activate human monocyte-derived dendritic cells and dominantly inhibit cytokine production through a cAMP-dependent pathway | Q28214681 | ||
Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein | Q28288262 | ||
Third activity of Bordetella adenylate cyclase (AC) toxin-hemolysin. Membrane translocation of AC domain polypeptide promotes calcium influx into CD11b+ monocytes independently of the catalytic and hemolytic activities | Q28485698 | ||
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells | Q29618163 | ||
Phenotypic and functional features of human Th17 cells | Q29619323 | ||
Albumin, in the Presence of Calcium, Elicits a Massive Increase in Extracellular Bordetella Adenylate Cyclase Toxin | Q30252682 | ||
Cyclic AMP-mediated suppression of neutrophil extracellular trap formation and apoptosis by the Bordetella pertussis adenylate cyclase toxin | Q30303150 | ||
Bordetella parapertussis Circumvents Neutrophil Extracellular Bactericidal Mechanisms. | Q30354234 | ||
Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3 | Q30360778 | ||
Quantification of the adenylate cyclase toxin of Bordetella pertussis in vitro and during respiratory infection | Q30416562 | ||
Contribution of Bordetella filamentous hemagglutinin and adenylate cyclase toxin to suppression and evasion of interleukin-17-mediated inflammation | Q30423650 | ||
Delivery of large heterologous polypeptides across the cytoplasmic membrane of antigen-presenting cells by the Bordetella RTX hemolysin moiety lacking the adenylyl cyclase domain | Q30425161 | ||
Adenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells. | Q30449654 | ||
Inhibition of monocyte oxidative responses by Bordetella pertussis adenylate cyclase toxin | Q30461145 | ||
Pertussis toxin stimulates IL-17 production in response to Bordetella pertussis infection in mice | Q30873716 | ||
T- and B-cell-mediated protection induced by novel, live attenuated pertussis vaccine in mice. Cross protection against parapertussis | Q33564283 | ||
Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN | Q33590435 | ||
Attenuated Bordetella pertussis vaccine candidate BPZE1 promotes human dendritic cell CCL21-induced migration and drives a Th1/Th17 response. | Q51015773 | ||
Phagocyte Impotence Caused by an Invasive Bacterial Adenylate Cyclase | Q51198248 | ||
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells. | Q53013441 | ||
Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease. | Q53597450 | ||
Adjuvant effects of adenylate cyclase toxin of Bordetella pertussis after intranasal immunisation of mice. | Q53604684 | ||
Pore-formation by adenylate cyclase toxoid activates dendritic cells to prime CD8+ and CD4+ T cells. | Q54242346 | ||
cAMP signalling of Bordetella adenylate cyclase toxin through the SHP-1 phosphatase activates the BimEL-Bax pro-apoptotic cascade in phagocytes. | Q55043889 | ||
Cell‐Mediated Immunity and Antibody Responses toBordetella pertussisAntigens in Children with a History of Pertussis Infection and in Recipients of an Acellular Pertussis Vaccine | Q59651744 | ||
Bordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme | Q38590644 | ||
Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface. | Q38652117 | ||
Bordetella pertussis Adenylate Cyclase Toxin Blocks Induction of Bactericidal Nitric Oxide in Macrophages through cAMP-Dependent Activation of the SHP-1 Phosphatase | Q38886825 | ||
Pertussis leukocytosis: mechanisms, clinical relevance and treatment | Q38949809 | ||
Bordetella pertussis entry into respiratory epithelial cells and intracellular survival | Q39119096 | ||
Adenyl Cyclase in Bordetella pertussis Vaccines | Q39160702 | ||
Bordetella pertussis virulence factors affect phagocytosis by human neutrophils | Q39514867 | ||
Lipopolysaccharides from Bordetella pertussis and Bordetella parapertussis differently modulate human dendritic cell functions resulting in divergent prevalence of Th17-polarized responses | Q39970329 | ||
Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis | Q40257250 | ||
GTL001, A Therapeutic Vaccine for Women Infected with Human Papillomavirus 16 or 18 and Normal Cervical Cytology: Results of a Phase I Clinical Trial | Q40649178 | ||
Follicular Helper T Cells | Q40780566 | ||
Modulation of host immune responses, induction of apoptosis and inhibition of NF-kappaB activation by the Bordetella type III secretion system | Q40894557 | ||
Intracellular trafficking of Bordetella pertussis in human macrophages | Q41880823 | ||
Both CD4⁺ and CD8⁺ lymphocytes participate in the IFN-γ response to filamentous hemagglutinin from Bordetella pertussis in infants, children, and adults | Q42045089 | ||
Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction | Q42047758 | ||
Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses | Q42206141 | ||
Bordetella pertussis commits human dendritic cells to promote a Th1/Th17 response through the activity of adenylate cyclase toxin and MAPK-pathways | Q42936693 | ||
Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis | Q42976933 | ||
Characterization of recombinant Bordetella pertussis adenylate cyclase toxins carrying passenger proteins | Q43839547 | ||
Both adenylate cyclase and hemolytic activities are required by Bordetella pertussis to initiate infection | Q44550891 | ||
The adenylate cyclase toxin contributes to the survival of Bordetella pertussis within human macrophages | Q44562622 | ||
Bordetella type III secretion and adenylate cyclase toxin synergize to drive dendritic cells into a semimature state | Q44987484 | ||
Adjuvanticity of native and detoxified adenylate cyclase toxin of Bordetella pertussis towards co-administered antigens | Q45098739 | ||
Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein. | Q45253754 | ||
cAMP Signaling of Adenylate Cyclase Toxin Blocks the Oxidative Burst of Neutrophils through Epac-Mediated Inhibition of Phospholipase C Activity | Q46438457 | ||
Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells | Q46490320 | ||
Adenylate cycalse toxin of Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells | Q46653871 | ||
Bordetella pertussis induces apoptosis in macrophages: role of adenylate cyclase-hemolysin. | Q33609798 | ||
Role of adenylate cyclase-hemolysin in alveolar macrophage apoptosis during Bordetella pertussis infection in vivo. | Q33752641 | ||
Probing the function of Bordetella bronchiseptica adenylate cyclase toxin by manipulating host immunity. | Q34000735 | ||
Bordetella pertussis pathogenesis: current and future challenges | Q34383541 | ||
Cell-mediated immunity to Bordetella pertussis: role of Th1 cells in bacterial clearance in a murine respiratory infection model | Q34522858 | ||
The role of innate mediators in inflammatory response | Q34636524 | ||
Adenylate cyclase toxin subverts phagocyte function by RhoA inhibition and unproductive ruffling | Q34844344 | ||
Adenylate cyclase toxin is critical for colonization and pertussis toxin is critical for lethal infection by Bordetella pertussis in infant mice | Q35106655 | ||
Complement evasion by Bordetella pertussis: implications for improving current vaccines | Q35197120 | ||
Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells. | Q35217146 | ||
Effect of different forms of adenylate cyclase toxin of Bordetella pertussis on protection afforded by an acellular pertussis vaccine in a murine model | Q35220336 | ||
Cell-invasive activity of epitope-tagged adenylate cyclase of Bordetella pertussis allows in vitro presentation of a foreign epitope to CD8+ cytotoxic T cells | Q35441983 | ||
Vaccine- and antigen-dependent type 1 and type 2 cytokine induction after primary vaccination of infants with whole-cell or acellular pertussis vaccines | Q35548872 | ||
The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses | Q35582560 | ||
Development and function of T helper 1 cells | Q35769454 | ||
The adenylate cyclase toxin from Bordetella pertussis--a novel promising vehicle for antigen delivery to dendritic cells | Q35776241 | ||
Signaling pathways in Th2 development | Q35951832 | ||
Tuning microenvironments: induction of regulatory T cells by dendritic cells | Q36151935 | ||
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells | Q36355239 | ||
Bordetella adenylate cyclase toxin: a swift saboteur of host defense | Q36365962 | ||
A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. | Q36403615 | ||
Protective immunity to Bordetella pertussis requires both B cells and CD4(+) T cells for key functions other than specific antibody production | Q36404631 | ||
Expanding the effector CD4 T-cell repertoire: the Th17 lineage. | Q36449975 | ||
Soluble adenylate cyclase from the culture medium of Bordetella pertussis: purification and characterization | Q36580106 | ||
Debugging how bacteria manipulate the immune response. | Q36739044 | ||
Foxp3 in control of the regulatory T cell lineage | Q36794299 | ||
Bordetella pertussis: new concepts in pathogenesis and treatment | Q36839952 | ||
Bordetella pertussis adenylate cyclase: effects of affinity-purified adenylate cyclase on human polymorphonuclear leukocyte functions | Q37015041 | ||
Bacteria and their toxins tamed for immunotherapy | Q37984514 | ||
IL-17A and Th17 cells in lung inflammation: an update on the role of Th17 cell differentiation and IL-17R signaling in host defense against infection. | Q38129869 | ||
Adenylate cyclase toxin-hemolysin relevance for pertussis vaccines | Q38236718 | ||
Differentiation, regulation and function of Th9 cells | Q38254788 | ||
Investigating pertussis toxin and its impact on vaccination | Q38358628 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 10 | |
P921 | main subject | cell | Q7868 |
enzyme | Q8047 | ||
pertussis | Q134859 | ||
infection | Q166231 | ||
neutrophil | Q188417 | ||
dendritic cell | Q506253 | ||
hemic and immune systems | Q70202933 | ||
P577 | publication date | 2017-09-21 | |
P1433 | published in | Toxins | Q15724569 |
P1476 | title | Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity | |
P478 | volume | 9 |
Q58698342 | An Introduction to the Toxins Special Issue on the Adenylate Cyclase Toxin |
Q90419622 | Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy |
Q92711371 | Bordetella Filamentous Hemagglutinin, a Model for the Two-Partner Secretion Pathway |
Q92538598 | Immunomodulation as a Novel Strategy for Prevention and Treatment of Bordetella spp. Infections |
Q90271081 | Membrane Activity and Channel Formation of the Adenylate Cyclase Toxin (CyaA) of Bordetella pertussis in Lipid Bilayer Membranes |
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