amiloride

chemical compound

Wikidata entity: Q419995

C₆H₈ClN₇O (P274)


Wikimedia Commons category is Amiloride



Quantities

P4250defined daily dose10
P2067mass229.048

P233 canonical SMILES String C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N ???
P373 Commons category String Amiloride ???
P366 has use ... Q12140 (medication) medication
P31 instance of ... Q113145171 (type of chemical entity) type of chemical entity
P2017 isomeric SMILES String C1(=C(N=C(C(=N1)Cl)N)N)/C(=N/C(=N)N)/O ???
P8026 LiverTox likelihood score ... Q83284515 (LiverTox toxicity likelihood category D) LiverTox toxicity likelihood category D
P2175 medical condition treated ... Q41861 (arterial hypertension) arterial hypertension
P2175 medical condition treated ... Q178194 (cystic fibrosis) cystic fibrosis
P2175 medical condition treated ... Q486485 (anasarka) anasarka
P2175 medical condition treated ... Q1124286 (polyuria) polyuria
P2175 medical condition treated ... Q794086 (hypokalemia) hypokalemia
P2175 medical condition treated ... Q2892779 (nephrogenic diabetes insipidus) nephrogenic diabetes insipidus
P2175 medical condition treated ... Q19000661 (congestive heart failure) congestive heart failure
P361 part of ... Q21422712 (amiloride transport) amiloride transport
P361 part of ... Q22273334 (response to amiloride) response to amiloride
P361 part of ... Q22273335 (cellular response to amiloride) cellular response to amiloride
P361 part of ... Q22324619 (amiloride transmembrane transporter activity) amiloride transmembrane transporter activity
P361 part of ... Q22324620 (amiloride:proton antiporter activity) amiloride:proton antiporter activity
P129 physically interacts with ... Q7671473 (Transient receptor potential cation channel subfamily C member 7) Transient receptor potential cation channel subfamily C member 7
P129 physically interacts with ... Q7671497 (Transient receptor potential cation channel subfamily V member 2) Transient receptor potential cation channel subfamily V member 2
P129 physically interacts with ... Q14914580 (Transient receptor potential cation channel, subfamily C, member 6) Transient receptor potential cation channel, subfamily C, member 6
P129 physically interacts with ... Q15323278 (Transient receptor potential cation channel, subfamily A, member 1) Transient receptor potential cation channel, subfamily A, member 1
P129 physically interacts with ... Q21102075 (Acid sensing ion channel subunit 1) Acid sensing ion channel subunit 1
P129 physically interacts with ... Q21102082 (Acid sensing ion channel subunit 2) Acid sensing ion channel subunit 2
P129 physically interacts with ... Q21102111 (Acid sensing ion channel subunit 3) Acid sensing ion channel subunit 3
P129 physically interacts with ... Q21123416 (Solute carrier family 9 member A5) Solute carrier family 9 member A5
P129 physically interacts with ... Q21126833 (Polycystin 2 like 1, transient receptor potential cation channel) Polycystin 2 like 1, transient receptor potential cation channel
P3489 pregnancy category ... Q28123616 (US pregnancy category B) US pregnancy category B
P769 significant drug interaction ... Q186969 (ibuprofen) ibuprofen
P769 significant drug interaction ... Q45050 (tenoxicam) tenoxicam
P769 significant drug interaction ... Q155472 (valsartan) valsartan
P769 significant drug interaction ... Q221520 (triamterene) triamterene
P769 significant drug interaction ... Q244408 (Diclofenac) Diclofenac
P769 significant drug interaction ... Q277785 (perindopril) perindopril
P769 significant drug interaction ... Q347941 (parecoxib) parecoxib
P769 significant drug interaction ... Q367700 (cyclosporine) cyclosporine
P769 significant drug interaction ... Q409231 (indomethacin) indomethacin
P769 significant drug interaction ... Q410074 (losartan) losartan
P769 significant drug interaction ... Q415970 (candesartan) candesartan
P769 significant drug interaction ... Q419890 ((±)-flurbiprofen) (±)-flurbiprofen
P769 significant drug interaction ... Q421119 (captopril) captopril
P769 significant drug interaction ... Q422185 (enalapril) enalapril
P769 significant drug interaction ... Q422665 (trimethoprim) trimethoprim
P769 significant drug interaction ... Q423804 (eplerenone) eplerenone
P769 significant drug interaction ... Q425207 (nabumetone) nabumetone
P769 significant drug interaction ... Q481757 (aceclofenac) aceclofenac
P769 significant drug interaction ... Q408676 (piroxicam) piroxicam
P769 significant drug interaction ... Q408801 (celecoxib) celecoxib
P769 significant drug interaction ... Q409192 ((RS)-ketoprofen) (RS)-ketoprofen
P769 significant drug interaction ... Q412666 (ramipril) ramipril
P769 significant drug interaction ... Q414028 (meloxicam) meloxicam
P769 significant drug interaction ... Q1215575 (naproxen) naproxen
P769 significant drug interaction ... Q2465218 ((RS)-etodolac) (RS)-etodolac
P769 significant drug interaction ... Q596022 (quinapril) quinapril
P769 significant drug interaction ... Q733186 (telmisartan) telmisartan
P769 significant drug interaction ... Q2555245 ((RS)-fenoprofen) (RS)-fenoprofen
P769 significant drug interaction ... Q47495698 (lisinopril dihydrate) lisinopril dihydrate
P769 significant drug interaction ... Q929420 (trandolapril) trandolapril
P769 significant drug interaction ... Q947266 (irbesartan) irbesartan
P769 significant drug interaction ... Q963093 (sulindac) sulindac
P9989 stylized name String aMILoride ???
P279 subclass of ... Q11173 (chemical compound) chemical compound
P2868 subject has role ... Q35456 (essential medicine) essential medicine
P2868 subject has role ... Q200656 (diuretic) diuretic
P2868 subject has role ... Q50430453 (Acid Sensing Ion Channel Blockers) Acid Sensing Ion Channel Blockers
P2868 subject has role ... Q50430455 (epithelial sodium channel blockers) epithelial sodium channel blockers
P2275 World Health Organisation international non-proprietary name Monolingualtext amiloride ???

External Ids
P267ATC codeC03DB01
P231CAS Registry Number2609-46-3
P683ChEBI ID2639
P592ChEMBL IDCHEMBL945
P661ChemSpider ID15403
P9272DeCS ID588
P715DrugBank IDDB00594
P11198DrugCentral ID158
P8494DSSTOX compound identifierDTXCID7023853
P3117DSSTox substance IDDTXSID9043853
P232EC number220-024-7
P2566ECHA Substance Infocard ID100.018.205
P9635electronic Essential Medicines List medicine ID176
P646Freebase ID/m/048px5
P595Guide to Pharmacology Ligand ID2421
P2057Human Metabolome Database IDHMDB0014732
P234InChIInChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)
P235InChIKeyXSDQTOBWRPYKKA-UHFFFAOYSA-N
P665KEGG IDC06821
P665KEGG IDD07447
P7830LiverTox IDAmiloride
P6689MassBank accession IDMSBNK-Keio_Univ-KO002393
P6689MassBank accession IDMSBNK-Keio_Univ-KO002394
P6689MassBank accession IDMSBNK-Keio_Univ-KO002395
P6689MassBank accession IDMSBNK-Keio_Univ-KO002396
P6689MassBank accession IDMSBNK-Keio_Univ-KO002397
P6689MassBank accession IDMSBNK-Keio_Univ-KO008833
P6689MassBank accession IDMSBNK-Keio_Univ-KO008834
P6689MassBank accession IDMSBNK-Keio_Univ-KO008835
P6689MassBank accession IDMSBNK-Waters-WA001192
P6689MassBank accession IDMSBNK-Waters-WA001193
P6689MassBank accession IDMSBNK-Waters-WA001194
P6689MassBank accession IDMSBNK-Waters-WA001195
P6689MassBank accession IDMSBNK-Waters-WA001196
P10245MedlinePlus drug identifiera615029
P6694MeSH concept IDM0000906
P486MeSH descriptor IDD000584
P672MeSH tree codeD03.383.679.149
P6366Microsoft Academic ID (discontinued)2779608910
P1368National Library of Latvia ID000311872
P2115NDF-RT IDN0000147699
P10283OpenAlex IDC2779608910
P4235PatientsLikeMe treatment IDamiloride
P3636PDB ligand IDAMR
P638PDB structure ID4NTX
P638PDB structure ID1F5L
P11199Probes And Drugs IDPD009902
P662PubChem CID16231
P1579Reaxys registry number657410
P1579Reaxys registry number616612
P3345RxNorm CUI644
P4964SPLASHsplash10-000i-0900000000-8f3aaddd905d255eeb9d
P4964SPLASHsplash10-0089-1790000000-9f966f1f1f39d074086a
P4964SPLASHsplash10-00di-0900000000-a76fa198e6f147ebf51f
P4964SPLASHsplash10-00di-3900000000-9e3a3741c916f113d456
P4964SPLASHsplash10-00dr-1910000000-f028ae70e2d968afae25
P4964SPLASHsplash10-02t9-8900000000-7f66a60319e15df262c2
P4964SPLASHsplash10-02tc-5900000000-f32cb47ea7e98516befc
P2877SureChEMBL ID27562
P2877SureChEMBL ID27563
P2892UMLS CUIC0002502
P11089UniChem compound ID483159
P652UNII7DZO8EB0Z3
P11143WikiProjectMed IDAmiloride
P3350World Health Organisation international non-proprietary name numeric ID2352

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