Optogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task

scientific article published on 4 November 2015

Optogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FNBEH.2015.00286
P932PMC publication ID4631833
P698PubMed publication ID26582980
P5875ResearchGate publication ID283976358

P2093author name stringFrank W Ohl
Jürgen Goldschmidt
Michael T Lippert
Hans-Jochen Heinze
Jennifer Tegtmeier
Kathrin Janitzky
Achim Engelhorn
P2860cites workTuning arousal with optogenetic modulation of locus coeruleus neuronsQ24594118
Behavioral flexibility in rats and mice: contributions of distinct frontocortical regionsQ28082180
Multimodal fast optical interrogation of neural circuitryQ28296635
Pharmacological stimulation of locus coeruleus reveals a new antipsychotic-responsive pathway for deficient sensorimotor gatingQ30466233
The mouse attentional-set-shifting task: a method for assaying successful cognitive aging?Q33879977
Uncertainty, neuromodulation, and attentionQ34424911
Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in manQ34649595
Adaptive gain and the role of the locus coeruleus-norepinephrine system in optimal performanceQ36299557
Induction of early growth response gene 2 expression in the forebrain of mice performing an attention-set-shifting taskQ36571538
Double dissociation of the effects of medial and orbital prefrontal cortical lesions on attentional and affective shifts in mice.Q37132044
Shining light on wakefulness and arousal.Q37167156
Noradrenergic modulation of cognition: therapeutic implicationsQ38091914
Evidence for broad versus segregated projections from cholinergic and noradrenergic nuclei to functionally and anatomically discrete subregions of prefrontal cortexQ41889003
Selective depletion of cortical noradrenaline by anti-dopamine beta-hydroxylase-saporin impairs attentional function and enhances the effects of guanfacine in the rat.Q42048110
Functional recovery of locus coeruleus noradrenergic neurons after DSP-4 lesion: effects on dopamine levels and neuroleptic induced-parkinsonian symptoms in ratsQ42455281
Chronic treatment with desipramine improves cognitive performance of rats in an attentional set-shifting testQ42503551
The effects of NMDA receptor antagonists on attentional set-shifting task performance in miceQ42703159
Noradrenergic lesion of the locus coeruleus increases the firing activity of the medial prefrontal cortex pyramidal neurons and the role of alpha2-adrenoceptors in normal and medial forebrain bundle lesioned ratsQ43163253
Noradrenergic, but not cholinergic, deafferentation of prefrontal cortex impairs attentional set-shiftingQ43211242
Effect of reversible inactivation of locus ceruleus on spatial reference and working memory.Q46223386
Noradrenergic modulation of cognitive function in rat medial prefrontal cortex as measured by attentional set shifting capabilityQ46812059
Lesions of the dorsal noradrenergic bundle impair attentional set-shifting in the rat.Q48116588
Animal neuropsychology: validation of the Intra-Dimensional Extra-Dimensional set shifting task for miceQ48471248
Lesions of the orbital prefrontal cortex impair the formation of attentional set in rats.Q48482293
Attentional set-shifting in mice: modification of a rat paradigm, and evidence for strain-dependent variationQ48683838
Activation of the noradrenergic system facilitates an attentional shift in the rat.Q48950597
Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycleQ49162619
Medial frontal cortex mediates perceptual attentional set shifting in the rat.Q52168274
Microbial opsins: a family of single-component tools for optical control of neural activityQ83506641
P921main subjectoptogeneticsQ781492
attentionQ6501338
P304page(s)286
P577publication date2015-11-04
P1433published inFrontiers in Behavioral NeuroscienceQ21971195
P1476titleOptogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task
P478volume9