scholarly article | Q13442814 |
P50 | author | D Allan Butterfield | Q66912067 |
P2093 | author name string | Susan A Farr | |
John E Morley | |||
M Paul Murphy | |||
Rukhsana Sultana | |||
Thomas L Platt | |||
Michael L Niehoff | |||
Vijaya Kumar | |||
Zhaoshu Zhang | |||
Jessica L Ripley | |||
P2860 | cites work | Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling | Q24298930 |
Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3beta (GSK3beta) plays a critical role in regulating tau's ability to bind and stabilize microtubules | Q24302556 | ||
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain | Q24609907 | ||
Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics | Q24685475 | ||
Measurement of protein using bicinchoninic acid | Q26778491 | ||
Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3. | Q48622377 | ||
Distribution, levels, and activity of glycogen synthase kinase-3 in the Alzheimer disease brain | Q48822557 | ||
Delivery across the blood-brain barrier of antisense directed against amyloid beta: reversal of learning and memory deficits in mice overexpressing amyloid precursor protein | Q48876526 | ||
Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice | Q49096995 | ||
Beta-amyloid precursor polypeptide in SAMP8 mice affects learning and memory | Q49097021 | ||
Activation of Akt by lithium: pro-survival pathways in aging. | Q50621066 | ||
Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal model of disturbances in recent memory. | Q52120589 | ||
Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II. | Q53322724 | ||
2013 Alzheimer's disease facts and figures | Q86421768 | ||
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides | Q28205921 | ||
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants | Q28218883 | ||
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements | Q28244853 | ||
Molecular cloning and expression of glycogen synthase kinase-3/factor A | Q28569645 | ||
Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress | Q29617845 | ||
Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes | Q30530899 | ||
Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition | Q33576221 | ||
Regulatory mechanisms of cellular response to oxidative stress | Q33750101 | ||
Judging a protein by more than its name: GSK-3. | Q34093128 | ||
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice | Q34449486 | ||
Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline | Q35840610 | ||
The many faces of tau | Q35870359 | ||
Selectively silencing GSK-3 isoforms reduces plaques and tangles in mouse models of Alzheimer's disease | Q36012200 | ||
Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target? | Q36063447 | ||
Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity | Q36464631 | ||
GSK-3 is essential in the pathogenesis of Alzheimer's disease. | Q36568147 | ||
The GSK3 hypothesis of Alzheimer's disease | Q37035378 | ||
AEG-35156, an antisense oligonucleotide against X-linked inhibitor of apoptosis for the potential treatment of cancer | Q37179130 | ||
From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). | Q37354749 | ||
Making sense of therapeutics using antisense technology | Q38014478 | ||
Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain | Q38050263 | ||
Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. | Q38318490 | ||
Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress | Q38355236 | ||
In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases. | Q39448933 | ||
Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2. | Q40473279 | ||
Divergent roles of GSK3 and CDK5 in APP processing | Q40611214 | ||
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. | Q41423732 | ||
Learning and memory in the SAMP8 mouse | Q41716293 | ||
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult. | Q44755335 | ||
Peripheral administration of antisense oligonucleotides targeting the amyloid-β protein precursor reverses AβPP and LRP-1 overexpression in the aged SAMP8 mouse brain | Q44777555 | ||
Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain | Q44944553 | ||
Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice | Q44985177 | ||
A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo. | Q45970893 | ||
Preproenkephalin targeted antisenses cross the blood-brain barrier to reduce brain methionine enkephalin levels and increase voluntary ethanol drinking | Q46757070 | ||
Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes | Q48105061 | ||
Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration | Q48163930 | ||
Increased level of active GSK-3beta in Alzheimer's disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration | Q48303820 | ||
Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert. | Q48389526 | ||
Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase | Q48406074 | ||
Lipid peroxidation in brain during aging in the senescence-accelerated mouse (SAM). | Q48469494 | ||
On the delay-dependent involvement of the hippocampus in object recognition memory | Q48542116 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P921 | main subject | Alzheimer's disease | Q11081 |
P304 | page(s) | 387-395 | |
P577 | publication date | 2013-12-16 | |
P1433 | published in | Free Radical Biology and Medicine | Q5500023 |
P1476 | title | Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease | |
P478 | volume | 67 |