Oxygen-dependent transcriptional regulator Hap1p limits glucose uptake by repressing the expression of the major glucose transporter gene RAG1 in Kluyveromyces lactis

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Oxygen-dependent transcriptional regulator Hap1p limits glucose uptake by repressing the expression of the major glucose transporter gene RAG1 in Kluyveromyces lactis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/EC.00018-08
P932PMC publication ID2583534
P698PubMed publication ID18806211

P50authorMonique Bolotin-FukuharaQ46820988
Claudia DonniniQ55691540
P2093author name stringHiroshi Fukuhara
Iliana Ferrero
Bernard Guiard
Wei-Guo Bao
Michel Gervais
Zi-An Fang
Flavia M Lopes Passos
P2860cites workThe Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity.Q27931159
CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast. I. Overall organization of the protein sequence displays several novel structural domainsQ27931840
Function and expression of flavohemoglobin in Saccharomyces cerevisiae. Evidence for a role in the oxidative stress responseQ27932551
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Glucose transport in the yeastKluyveromyces lactisQ60240028
Inverse Polymerase Chain ReactionQ62089450
CYP1 (HAP1) is a determinant effector of alternative expression of heme-dependent transcription in yeastQ67699382
Expression of the gene encoding subunit II of yeast QH2: cytochrome c oxidoreductase is regulated by multiple factorsQ68474276
Yeast HAP1 activator competes with the factor RC2 for binding to the upstream activation site UAS1 of the CYC1 geneQ70169588
Isolation and molecular analysis of the gene for cytochrome c1 from Kluyveromyces lactisQ71138528
[Method for the determination of cytochrome concentrations in whole yeast cells]Q71585737
New vectors for combinatorial deletions in yeast chromosomes and for gap-repair cloning using 'split-marker' recombinationQ71843156
Regulation of cytochrome c expression in the aerobic respiratory yeast Kluyveromyces lactisQ72589623
Regulation of Saccharomyces cerevisiae flavohemoglobin gene expressionQ72645724
Heme-mediated transcriptional control in Kluyveromyces lactisQ73319791
Anaerobic nutrition of Saccharomyces cerevisiae. II. Unsaturated fatty acid requirement for growth in a defined mediumQ73587623
Regulation of alcoholic fermentation in batch and chemostat cultures of Kluyveromyces lactis CBS 2359Q74480606
The role of zinc in alcohol dehydrogenase. V. The effect of metal-binding agents on thestructure of the yeast alcohol dehydrogenase moleculeQ79029108
A rapid and simple method for preparation of RNA from Saccharomyces cerevisiaeQ28131648
Yeast carbon catabolite repressionQ29622932
Cloning and characterization of the lactate-specific inducible gene KlCYB2, encoding the cytochrome b(2) of Kluyveromyces lactisQ30870189
Mga2p processing by hypoxia and unsaturated fatty acids in Saccharomyces cerevisiae: impact on LORE-dependent gene expressionQ33904078
Mutations in MGI genes convert Kluyveromyces lactis into a petite-positive yeast.Q33960514
Evidence for an interaction between the CYP1(HAP1) activator and a cellular factor during heme-dependent transcriptional regulation in the yeast Saccharomyces cerevisiae.Q34046735
Genomic exploration of the hemiascomycetous yeasts: 1. A set of yeast species for molecular evolution studiesQ34127806
Molecular mechanism of heme signaling in yeast: the transcriptional activator Hap1 serves as the key mediator.Q34158451
Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response.Q34304272
Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for growth in a defined mediumQ34537071
The transcriptional regulator Hap1p (Cyp1p) is essential for anaerobic or heme-deficient growth of Saccharomyces cerevisiae: Genetic and molecular characterization of an extragenic suppressor that encodes a WD repeat proteinQ34602594
The Kluyver effect revisitedQ35128006
Regulation of gene expression by oxygen in Saccharomyces cerevisiaeQ36080192
Factors involved in anaerobic growth of Saccharomyces cerevisiaeQ36694165
Positive and negative transcriptional control by heme of genes encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiaeQ36798268
A single Saccharomyces cerevisiae upstream activation site (UAS1) has two distinct regions essential for its activityQ36902542
A microarray-assisted screen for potential Hap1 and Rox1 target genes in Saccharomyces cerevisiaeQ38287289
Functional characterization of KlHAP1: a model to foresee different mechanisms of transcriptional regulation by Hap1p in yeastsQ38297282
Regulation of the Saccharomyces cerevisiae DLD1 gene encoding the mitochondrial protein D-lactate ferricytochrome c oxidoreductase by HAP1 and HAP2/3/4/5.Q38316715
Positive and negative elements involved in the differential regulation by heme and oxygen of the HEM13 gene (coproporphyrinogen oxidase) in Saccharomyces cerevisiaeQ39470690
Three target genes for the transcriptional activator Cat8p of Kluyveromyces lactis: acetyl coenzyme A synthetase genes KlACS1 and KlACS2 and lactate permease gene KlJEN1.Q39504695
Molecular mechanism governing heme signaling in yeast: a higher-order complex mediates heme regulation of the transcriptional activator HAP1.Q39575132
Global regulatory functions of Oaf1p and Pip2p (Oaf2p), transcription factors that regulate genes encoding peroxisomal proteins in Saccharomyces cerevisiaeQ39576537
Misconceptions about the energy metabolism of Saccharomyces cerevisiaeQ39705317
Mutations in target DNA elements of yeast HAP1 modulate its transcriptional activity without affecting DNA bindingQ39716020
Glucose uptake in Kluyveromyces lactis: role of the HGT1 gene in glucose transport.Q39843048
Regulation of the yeast CYT1 gene encoding cytochrome c1 by HAP1 and HAP2/3/4Q40640994
Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeastQ41724822
Glucose transport in the yeast Kluyveromyces lactis. II. Transcriptional regulation of the glucose transporter gene RAG1.Q43439921
Carbon source-dependent transcriptional regulation of the QCR8 gene in Kluyveromyces lactis. Identification fo cis-acting regions and trans-acting factors in the KlQCR8 upstream regionQ43721745
A mechanism of oxygen sensing in yeast. Multiple oxygen-responsive steps in the heme biosynthetic pathway affect Hap1 activityQ44598331
HAP4, the glucose-repressed regulated subunit of the HAP transcriptional complex involved in the fermentation-respiration shift, has a functional homologue in the respiratory yeast Kluyveromyces lactisQ47976479
Influence of mutations in hexose-transporter genes on glucose repression in Kluyveromyces lactisQ48042764
Multiple regulatory elements control expression of the gene encoding the Saccharomyces cerevisiae cytochrome P450, lanosterol 14 alpha-demethylase (ERG11)Q48188900
Regulation of primary carbon metabolism in Kluyveromyces lactisQ58379968
P4510describes a project that usesImageQuantQ112270642
P433issue11
P921main subjectglucoseQ37525
glycobiologyQ899224
Kluyveromyces lactisQ6421540
P304page(s)1895-1905
P577publication date2008-09-19
P1433published inEukaryotic CellQ5408685
P1476titleOxygen-dependent transcriptional regulator Hap1p limits glucose uptake by repressing the expression of the major glucose transporter gene RAG1 in Kluyveromyces lactis
P478volume7

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cites work (P2860)
Q34639484Functional study of the Hap4-like genes suggests that the key regulators of carbon metabolism HAP4 and oxidative stress response YAP1 in yeast diverged from a common ancestor
Q33512530Gene responses to oxygen availability in Kluyveromyces lactis: an insight on the evolution of the oxygen-responding system in yeast
Q35238195Genetic basis of the highly efficient yeast Kluyveromyces marxianus: complete genome sequence and transcriptome analyses
Q34425629Genome-wide metabolic (re-) annotation of Kluyveromyces lactis
Q38038606Kluyveromyces lactis: a suitable yeast model to study cellular defense mechanisms against hypoxia-induced oxidative stress.
Q38086031Regulations of sugar transporters: insights from yeast
Q35133655Statistics-based model for prediction of chemical biosynthesis yield from Saccharomyces cerevisiae
Q42573302Sugar metabolism, redox balance and oxidative stress response in the respiratory yeast Kluyveromyces lactis
Q38046096The yeast hypoxic responses, resources for new biotechnological opportunities
Q51627642Unsaturated fatty acids-dependent linkage between respiration and fermentation revealed by deletion of hypoxic regulatory KlMGA2 gene in the facultative anaerobe-respiratory yeast Kluyveromyces lactis.
Q38098125Yeast on the milky way: genetics, physiology and biotechnology of Kluyveromyces lactis

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