Origins of P450 diversity

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Origins of P450 diversity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1098/RSTB.2012.0428
P932PMC publication ID3538418
P698PubMed publication ID23297351
P5875ResearchGate publication ID234087116

P50authorRené FeyereisenQ54656159
Gaelle Le GoffQ73573375
P2093author name stringHideki Sezutsu
P2860cites workCytochromes P450: a success storyQ21194891
The frailty of adaptive hypotheses for the origins of organismal complexityQ22066346
Constraints and plasticity in genome and molecular-phenome evolutionQ24594789
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its DisordersQ24613957
Correlating traits of gene retention, sequence divergence, duplicability and essentiality in vertebrates, arthropods, and fungiQ24632926
Identification of PpoA from Aspergillus nidulans as a fusion protein of a fatty acid heme dioxygenase/peroxidase and a cytochrome P450Q24655007
Duplicated genes evolve slower than singletons despite the initial rate increaseQ24793408
Preferential duplication of conserved proteins in eukaryotic genomesQ24800147
Organization and evolution of the Cyp2 gene cluster on mouse chromosome 7, and comparison with the syntenic human clusterQ24816889
Structural insights into the evolutionary paths of oxylipin biosynthetic enzymesQ27651731
The evolutionary fate and consequences of duplicate genesQ27861065
The cytochrome P450 genesis locus: the origin and evolution of animal cytochrome P450sQ28710080
Extensive synteny conservation of holocentric chromosomes in Lepidoptera despite high rates of local genome rearrangementsQ28752244
Gene loss, protein sequence divergence, gene dispensability, expression level, and interactivity are correlated in eukaryotic evolutionQ31006545
Transposable elements are enriched within or in close proximity to xenobiotic-metabolizing cytochrome P450 genesQ33279847
Daphnia Halloween genes that encode cytochrome P450s mediating the synthesis of the arthropod molting hormone: evolutionary implicationsQ33321069
Copy number variation and transposable elements feature in recent, ongoing adaptation at the Cyp6g1 locusQ33619213
Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatmentQ33702276
Cytochrome P450 and the individuality of speciesQ33720420
Mutational bias shaping fly copy number variation: implications for genome evolutionQ33886432
Dating the primigenial C4-CYP21 duplication in primatesQ33960897
Conversion events in gene clustersQ33974268
Unusual P450 reactions in plant secondary metabolism.Q34141661
The molecular basis of dominance.Q34283978
Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and futureQ34310938
Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activationQ34311371
High spontaneous rate of gene duplication in Caenorhabditis elegansQ34667651
Distinguishing among evolutionary models for the maintenance of gene duplicatesQ34992045
A different function for a member of an ancient and highly conserved cytochrome P450 family: from essential sterols to plant defense.Q35161327
Origins and impact of constraints in evolution of gene familiesQ35173702
A single amino acid substitution (F363I) converts the regiochemistry of the spearmint (-)-limonene hydroxylase from a C6- to a C3-hydroxylaseQ35355051
A common framework for understanding the origin of genetic dominance and evolutionary fates of gene duplicationsQ35818445
Unresolved boundaries of evolutionary theory and the question of how inheritance systems evolve: 75 years of debate on the evolution of dominanceQ36256808
Role of selection in fixation of gene duplicationsQ36293779
Human cytochromes P450 in health and diseaseQ36512912
Approaches to deorphanization of human and microbial cytochrome P450 enzymes.Q37759731
Arthropod CYPomes illustrate the tempo and mode in P450 evolution.Q37769952
Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidationQ37941781
Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in DipteraQ40236893
Molecular biology and evolution of resistance of toxicantsQ41074197
Evaluation of the role of CYP6B cytochrome P450s in pyrethroid resistant Australian Helicoverpa armigera.Q42034652
A world of cytochrome P450sQ42544418
Structure conservation in cytochromes P450.Q42643528
Genomic structures of Cyp9m10 in pyrethroid resistant and susceptible strains of Culex quinquefasciatus.Q42666529
CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolismQ42722391
PpoC from Aspergillus nidulans is a fusion protein with only one active haemQ43251713
The power-law distribution of gene family size is driven by the pseudogenisation rate's heterogeneity between gene familiesQ43436140
New aspects on lanosterol 14alpha-demethylase and cytochrome P450 evolution: lanosterol/cycloartenol diversification and lateral transferQ45071483
Abolition of oxygenase function, retention of NADPH oxidase activity, and emergence of peroxidase activity upon replacement of the axial cysteine-436 ligand by histidine in cytochrome P450 2B4.Q45209180
Arabidopsis cyp51 mutant shows postembryonic seedling lethality associated with lack of membrane integrityQ46616092
An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraeaQ48229189
Power-Law Distributions in Empirical DataQ50377899
Mathematics. Critical truths about power laws.Q51425987
Evolution of the CYP2D gene cluster in humans and four non-human primates.Q51558530
The cytochrome P450 gene family CYP157 does not contain EXXR in the K-helix reducing the absolute conserved P450 residues to a single cysteine.Q52002409
Two independent duplications forming the Cyp307a genes in Drosophila.Q52683258
Cytochrome P-450 55A1 (P-450dNIR) acts as nitric oxide reductase employing NADH as the direct electron donor.Q53807769
Gene copy-number polymorphism in nature.Q55498998
A P450-centric view of plant evolutionQ56989979
Oxygen activation by P450cin: Protein and substrate mutagenesisQ63383256
Substrate specificity of 6-deoxyerythronolide B hydroxylase, a bacterial cytochrome P450 of erythromycin A biosynthesisQ70597106
A Map of the MouseCyp3aLocusQ79081735
Evolution of the CYP2ABFGST gene cluster in rat, and a fine-scale comparison among rodent and primate speciesQ81312529
P433issue1612
P407language of work or nameEnglishQ1860
P304page(s)20120428
P577publication date2013-01-06
P1433published inPhilosophical Transactions of the Royal Society BQ2153239
P1476titleOrigins of P450 diversity
P478volume368

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cites work (P2860)
Q42544418A world of cytochrome P450s
Q37378656CYP101J2, CYP101J3, and CYP101J4, 1,8-Cineole-Hydroxylating Cytochrome P450 Monooxygenases from Sphingobium yanoikuyae Strain B2.
Q111349200Characterization of P450 monooxygenase gene family in the cotton aphid, Aphis gossypii Glover
Q101411035Characterization of Shed genes encoding ecdysone 20-monooxygenase (CYP314A1) in the Y-organ of the blackback land crab, Gecarcinus lateralis
Q46689973Coevolution can explain defensive secondary metabolite diversity in plants
Q61801683Combined Toxicity of Insecticides and Fungicides Applied to California Almond Orchards to Honey Bee Larvae and Adults
Q27335878Comparative analysis of P450 signature motifs EXXR and CXG in the large and diverse kingdom of fungi: identification of evolutionarily conserved amino acid patterns characteristic of P450 family
Q35832714Comparison of orthologous cytochrome P450 genes relative expression patterns in the bark beetles Dendroctonus rhizophagus and Dendroctonus valens (Curculionidae: Scolytinae) during host colonization.
Q90291368Complex gene expansion of the CYP2D gene subfamily
Q27303244Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders
Q41985941Cytochrome P450 diversification and hostplant utilization patterns in specialist and generalist moths: Birth, death and adaptation.
Q38947825Cytochrome P450s from the fall armyworm (Spodoptera frugiperda): responses to plant allelochemicals and pesticides
Q38429569Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.
Q38385149Directed evolution of cytochrome P450 enzymes for biocatalysis: exploiting the catalytic versatility of enzymes with relaxed substrate specificity.
Q35803265Diversity and evolution of cytochrome P450 monooxygenases in Oomycetes
Q57456951Firefly genomes illuminate parallel origins of bioluminescence in beetles
Q47148447Functional Study of Cytochrome P450 Enzymes from the Brown Planthopper (Nilaparvata lugens Stål) to Analyze Its Adaptation to BPH-Resistant Rice
Q28654898Fungal cytochrome p450 monooxygenases: their distribution, structure, functions, family expansion, and evolutionary origin
Q55332450Genome-wide analysis of cytochrome P450s of Trichoderma spp.: annotation and evolutionary relationships.
Q54015031Genomic adaptation to polyphagy and insecticides in a major East Asian noctuid pest.
Q52782611Insect P450 inhibitors and insecticides: challenges and opportunities.
Q51734569Intraspecific comparative genomics of isolates of the Norway spruce pathogen (Heterobasidion parviporum) and identification of its potential virulence factors.
Q48141368Molecular elucidation of a new allelic variation at the Sg-5 gene associated with the absence of group A saponins in wild soybean
Q35569844Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion
Q37247902Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s
Q91724372Origin and evolution of the CYP4G subfamily in insects, cytochrome P450 enzymes involved in cuticular hydrocarbon synthesis
Q96683704Phylogeny, evolution, and potential ecological relationship of cytochrome CYP52 enzymes in Saccharomycetales yeasts
Q38072419Plant P450s as versatile drivers for evolution of species-specific chemical diversity.
Q38585699Plant cytochrome P450s: nomenclature and involvement in natural product biosynthesis
Q88308200Retained duplications and deletions of CYP2C genes among primates
Q30378241Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450.
Q34497317The Cytochrome P450 superfamily complement (CYPome) in the annelid Capitella teleta
Q28710080The cytochrome P450 genesis locus: the origin and evolution of animal cytochrome P450s
Q28554345Utility of a Phylogenetic Perspective in Structural Analysis of CYP72A Enzymes from Flowering Plants
Q26739208Versatile biocatalysis of fungal cytochrome P450 monooxygenases

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