A high-throughput fluorescence polarization assay specific to the CD4 binding site of HIV-1 glycoproteins based on a fluorescein-labelled CD4 mimic

scientific article published on August 2005

A high-throughput fluorescence polarization assay specific to the CD4 binding site of HIV-1 glycoproteins based on a fluorescein-labelled CD4 mimic is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ20041953
P932PMC publication ID1184560
P698PubMed publication ID15836438

P50authorCatherine A. RoyerQ41547557
P2093author name stringLoïc Martin
Christian Roumestand
Philippe Barthe
Vivian Pogenberg
Claudio Vita
Alain Mechulam
François Stricher
Francisco Veas
André Menez
P2860cites workEnergetics of the HIV gp120-CD4 binding reactionQ22254716
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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibodyQ27759364
Torsion angle dynamics for NMR structure calculation with the new program DYANAQ27860808
Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South AmericaQ28183380
Stilbene disulfonic acids. CD4 antagonists that block human immunodeficiency virus type-1 growth at multiple stages of the virus life cycleQ28328594
Structure of an unliganded simian immunodeficiency virus gp120 coreQ29616089
Numerical analysis of binding data: advantages, practical aspects, and implicationsQ30987617
Gifa V. 4: A complete package for NMR data set processing.Q33699055
Dissociation of the CD4 and CXCR4 binding properties of human immunodeficiency virus type 1 gp120 by deletion of the first putative alpha-helical conserved structure.Q33783829
Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120Q33797964
HIV chemotherapyQ34223088
Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoproteinQ34347265
Crystal structure of an HIV-binding recombinant fragment of human CD4.Q34637157
Structural basis of macromolecular recognitionQ35014298
Inhibitors of the entry of HIV into host cells.Q35210147
The entry of entry inhibitors: a fusion of science and medicineQ35976966
A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor bindingQ35978823
Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactionsQ36525116
Improvements in the numerical analysis of thermodynamic data from biomolecular complexes.Q36782400
Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155.Q37010292
Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteinsQ37415987
Competition between baculovirus polyhedrin and p10 gene expression during infection of insect cellsQ40044829
FP-21399 blocks HIV envelope protein-mediated membrane fusion and concentrates in lymph nodesQ41119643
Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactionsQ44488145
Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopesQ45052086
Analysis of binding in macromolecular complexes: a generalized numerical approachQ45157769
Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadthQ45465741
1 Equilibrium and kinetic inhibition assays based upon fluorescence polarizationQ52744661
Bathophenanthroline Disulfonate and Soluble CD4 as Probes for Early Events of HIV Type 1 EntryQ60548839
Pseudo-structures for the 20 common amino acids for use in studies of protein conformations by measurements of intramolecular proton-proton distance constraints with nuclear magnetic resonanceQ70170789
HIV-1 entry - an expanding portal for drug discoveryQ73734846
New developments in anti-HIV chemotherapyQ74526095
P433issuePt 1
P407language of work or nameEnglishQ1860
P1104number of pages11
P304page(s)29-39
P577publication date2005-08-01
P1433published inBiochemical JournalQ864221
P1476titleA high-throughput fluorescence polarization assay specific to the CD4 binding site of HIV-1 glycoproteins based on a fluorescein-labelled CD4 mimic
P478volume390

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cites work (P2860)
Q37102810A simple one-step method for the preparation of HIV-1 envelope glycoprotein immunogens based on a CD4 mimic peptide
Q35140318A tyrosine-sulfated CCR5-mimetic peptide promotes conformational transitions in the HIV-1 envelope glycoprotein
Q27651139Combinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope Glycoprotein
Q41870179Depolarization of surface-enhanced fluorescence: an approach to fluorescence polarization assays
Q33524716Identification and characterization of the first small molecule inhibitor of MDMX
Q27659930Magnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutS
Q36127736MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency
Q35065249Stabilization of HIV-1 envelope in the CD4-bound conformation through specific cross-linking of a CD4 mimetic
Q36559665Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and coreceptor binding sites of HIV-1 gp120

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