Kaposi's sarcoma-associated herpesvirus latent protein LANA interacts with HIF-1 alpha to upregulate RTA expression during hypoxia: Latency control under low oxygen conditions

scientific article published on August 2006

Kaposi's sarcoma-associated herpesvirus latent protein LANA interacts with HIF-1 alpha to upregulate RTA expression during hypoxia: Latency control under low oxygen conditions is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.00689-06
P8608Fatcat IDrelease_i4in6pvlojgq5koafkt444ttzi
P932PMC publication ID1563785
P698PubMed publication ID16873253

P50authorSubhash VermaQ57951657
Erle S RobertsonQ88590600
P2093author name stringKe Lan
Qiliang Cai
Huaxin Si
Doug Lin
P2860cites workPhysical and functional interactions between STAT3 and Kaposi's sarcoma-associated herpesvirus-encoded LANAQ24299259
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxiaQ24315006
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1Q24316075
Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirusQ24561400
The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigenQ24672438
HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5'UTRQ28140700
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated MacrophagesQ28143066
HIF-1 and human disease: one highly involved factorQ28144179
Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and activate transcriptionQ28235557
Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functionsQ28251400
Hypoxia--a key regulatory factor in tumour growthQ29547318
Identification of a major latent nuclear antigen, LNA-1, in the human herpesvirus 8 genomeQ30668836
A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirusQ33559699
Kaposi's sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathwayQ33737793
Identification of the immediate-early transcripts of Kaposi's sarcoma-associated herpesvirusQ33815257
DNA binding and modulation of gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirusQ33853499
p53 inhibition by the LANA protein of KSHV protects against cell deathQ33885642
Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) binds ATF4/CREB2 and inhibits its transcriptional activation activityQ33922095
Regulation and autoregulation of the promoter for the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirusQ34292265
Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alphaQ34346992
The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cellsQ34511161
Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) contains hypoxia response elements: relevance to lytic induction by hypoxiaQ35019982
Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphomaQ35131811
The hypoxia-inducible factor-1 DNA recognition site is cAMP-responsiveQ38348904
Transcriptional activation by the product of open reading frame 50 of Kaposi's sarcoma-associated herpesvirus is required for lytic viral reactivation in B cellsQ39596534
Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1.Q39992257
STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cellsQ40416582
Role of CBP in regulating HIF-1-mediated activation of transcription.Q40477750
Transcriptional coactivation of c-Jun by the KSHV-encoded LANA.Q40635358
Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1.Q40747151
Hypoxia induces lytic replication of Kaposi sarcoma-associated herpesvirusQ40807418
The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus transactivates the telomerase reverse transcriptase promoterQ40811288
Auto-activation of the rta gene of human herpesvirus-8/Kaposi's sarcoma-associated herpesvirusQ40841209
Oxygen sensing and molecular adaptation to hypoxiaQ41075727
Expression of erythropoietin and erythropoietin receptor in non-small cell lung carcinomas.Q53781648
Tumor hypoxia in pelvic recurrences of cervical cancer.Q54128665
Targeting gene expression to hypoxic tumor cellsQ57377984
Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1Q63565692
Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R proteinQ77760836
Influence of the hypoxic subvolume on the survival of patients with head and neck cancerQ77936400
P433issue16
P407language of work or nameEnglishQ1860
P921main subjecthypoxiaQ105688
P304page(s)7965-7975
P577publication date2006-08-01
P1433published inJournal of VirologyQ1251128
P1476titleKaposi's sarcoma-associated herpesvirus latent protein LANA interacts with HIF-1 alpha to upregulate RTA expression during hypoxia: Latency control under low oxygen conditions
P478volume80

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cites work (P2860)
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