Structural and functional similarities between the central eukaryotic initiation factor (eIF)4A-binding domain of mammalian eIF4G and the eIF4A-binding domain of yeast eIF4G.

scientific article published on April 2001

Structural and functional similarities between the central eukaryotic initiation factor (eIF)4A-binding domain of mammalian eIF4G and the eIF4A-binding domain of yeast eIF4G. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/0264-6021:3550223
P932PMC publication ID1221730
P698PubMed publication ID11256967
P5875ResearchGate publication ID12075593

P2093author name stringTrachsel H
Dominguez D
Altmann M
Kislig E
P2860cites workEukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AIIQ22010667
Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4AQ24308808
A novel functional human eukaryotic translation initiation factor 4GQ24317414
DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell deathQ24319844
The Translation Initiation Factor eIF-4E Binds to a Common Motif Shared by the Translation Factor eIF-4γ and the Translational Repressors 4E-Binding ProteinsQ24336014
A new translational regulator with homology to eukaryotic translation initiation factor 4GQ24532110
Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4EQ24533512
Transformation of intact yeast cells treated with alkali cationsQ24672708
Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicaseQ27876214
Eukaryotic translation initiation factors 4G and 4A from Saccharomyces cerevisiae interact physically and functionallyQ27934834
Requirement of the DEAD-Box protein ded1p for messenger RNA translationQ27935125
Interaction of translation initiation factor eIF4G with eIF4A in the yeast Saccharomyces cerevisiaeQ27935298
A mitochondrial RNA maturase gene transferred to the yeast nucleus can control mitochondrial mRNA splicingQ27936770
Posttranscriptional control of gene expression in yeast.Q27937074
The Cap-binding protein eIF4E promotes folding of a functional domain of yeast translation initiation factor eIF4G1.Q27938001
Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families.Q27939047
TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential functionQ27940114
An essential yeast protein, encoded by duplicated genes TIF1 and TIF2 and homologous to the mammalian translation initiation factor eIF-4A, can suppress a mitochondrial missense mutationQ27940345
A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzymeQ28589367
Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexesQ28608941
Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entryQ29614570
Mapping of functional domains in eukaryotic protein synthesis initiation factor 4G (eIF4G) with picornaviral proteases. Implications for cap-dependent and cap-independent translational initiationQ29615969
Isolation of autophagocytosis mutants of Saccharomyces cerevisiaeQ29617037
Starting at the beginning, middle, and end: translation initiation in eukaryotesQ29618231
Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeastQ29618547
Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4GQ29620263
Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translationQ29620293
Birth of the D-E-A-D boxQ29620352
eIF4E activity is regulated at multiple levelsQ33601634
Translation in Saccharomyces cerevisiae: initiation factor 4A-dependent cell-free systemQ34295448
Cloning of eukaryotic protein synthesis initiation factor genes: isolation and characterization of cDNA clones encoding factor eIF-4A.Q35561547
The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiaeQ36468946
RNA unwinding in translation: assembly of helicase complex intermediates comprising eukaryotic initiation factors eIF-4F and eIF-4BQ36743330
Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory regionQ39450286
RNA recognition motif 2 of yeast Pab1p is required for its functional interaction with eukaryotic translation initiation factor 4G.Q39631106
mRNA translation: influence of the 5' and 3' untranslated regionsQ40672473
Initiation of protein synthesis in eukaryotic cellsQ41006460
eIF4G: a multipurpose ribosome adapter?Q41340426
eIF4G: translation's mystery factor begins to yield its secrets.Q41608684
Mutational analysis of the functional domains of the large subunit of the isozyme form of wheat initiation factor eIF4F.Q54575506
High-level synthesis in Escherichia coli of functional cap-binding eukaryotic initiation factor eIF-4E and affinity purification using a simplified cap-analog resinQ68067746
Expression of translation initiation factor 4A from yeast and mouse in Saccharomyces cerevisiaeQ68357354
Involvement of eukaryotic initiation factor 4A in the cap recognition processQ70992213
P433issuePt 1
P407language of work or nameEnglishQ1860
P304page(s)223-230
P577publication date2001-04-01
P1433published inBiochemical JournalQ864221
P1476titleStructural and functional similarities between the central eukaryotic initiation factor (eIF)4A-binding domain of mammalian eIF4G and the eIF4A-binding domain of yeast eIF4G.
P478volume355

Reverse relations

cites work (P2860)
Q26852951'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)
Q42321544Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress
Q27468894Coupling between the DEAD-box RNA helicases Ded1p and eIF4A
Q24657441Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions
Q36477548Eukaryotic initiation factor 4B and the poly(A)-binding protein bind eIF4G competitively
Q28202018Eukaryotic initiation factors 4A (eIF4A) and 4G (eIF4G) mutually interact in a 1:1 ratio in vivo
Q33531761Functional overlap between eIF4G isoforms in Saccharomyces cerevisiae
Q42816046Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1.
Q42236502Identification and bioinformatics characterization of translation initiation complex eIF4F components and poly(A)-binding protein from Plasmodium falciparum.
Q42868567Interaction of yeast eIF4G with spliceosome components: implications in pre-mRNA processing events.
Q35192105Molecular mechanism of scanning and start codon selection in eukaryotes
Q27939453RNA-binding activity of translation initiation factor eIF4G1 from Saccharomyces cerevisiae
Q30497757Stress-specific composition, assembly and kinetics of stress granules in Saccharomyces cerevisiae
Q27935513Yeast eukaryotic initiation factor 4B (eIF4B) enhances complex assembly between eIF4A and eIF4G in vivo
Q51976069Yeast phenotypic assays on translational control.

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