Large-scale culture system of human CD4+ helper/killer T cells for the application to adoptive tumour immunotherapy

scientific article published on July 1, 1992

Large-scale culture system of human CD4+ helper/killer T cells for the application to adoptive tumour immunotherapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/BJC.1992.210
P953full work available at URLhttps://europepmc.org/articles/PMC1977880
https://europepmc.org/articles/PMC1977880?pdf=render
P932PMC publication ID1977880
P698PubMed publication ID1353365
P5875ResearchGate publication ID21803075

P2093author name stringN. Kobayashi
Y. Nakamura
S. Kato
H. Tsukamoto
T. Nishimura
T. Mitomi
M. Iwasawa
Y. Tokuda
S. Habu
M. Kidokoro
P2860cites workObservations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancerQ34194434
Augmentation of the anti-tumor therapeutic efficacy of long-term cultured T lymphocytes by in vivo administration of purified interleukin 2.Q36346369
Augmentation of cell number and LAK activity in peripheral blood mononuclear cells activated with anti-CD3 and interleukin-2. Preliminary results in children with acute lymphocytic leukemia and neuroblastomaQ41293733
Bispecific Antibody-directed Antitumor Activity of Human CD4+Helper/Killer T Cells Induced by Anti-CD3 Monoclonal Antibody plus Interleukin 2Q41657844
Induction of cytotoxicity in human T cells coated with anti-glioma x anti-CD3 bispecific antibody against human glioma cellsQ41742682
Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor responseQ41744259
Characterization of interleukin-2-initiated versus OKT3-initiated human tumor-infiltrating lymphocytes from glioblastoma multiforme: growth characteristics, cytolytic activity, and cell phenotypeQ41769462
Preliminary trial of specific targeting therapy against malignant gliomaQ41885657
A murine monoclonal antibody that recognizes an extracellular domain of the human c-erbB-2 protooncogene productQ42800730
Diet and gastric cancer. A case-control study in BelgiumQ43918500
Macrophage-T cell interaction is essential for the induction of p75 interleukin 2 (IL-2) receptor and IL-2 responsiveness in human CD4+ T cellsQ46300243
Application of a human T cell line derived from a Sézary syndrome patient for human interleukin 4 assay.Q52834144
Interleukin 2 (IL-2) activity during tumor growth: IL-2 production kinetics, absorption of and responses to exogenous IL-2Q53553480
Generation propagation, and targeting of human CD4+ helper/killer T cells induced by anti-CD3 monoclonal antibody plus recombinant IL-2. An efficient strategy for adoptive tumor immunotherapy.Q55483828
Augmentation of the therapeutic efficacy of adoptive tumor immunotherapy by in vivo administration of slowly released recombinant interleukin 2Q63965639
Stimulation and inhibition of human T cell subsets by wheat germ agglutininQ67283648
Thymic stromal cell clone with nursing activity supports the growth and differentiation of murine CD4+8+ thymocytes in vitroQ68163830
Immunotherapy of cancer using local administration of lymphoid cells transformed by IL-2 cDNA and constitutively producing IL-2Q68802643
Mechanism of inhibition and induction of cytolytic activity in cytotoxic T lymphocytes by CD3 monoclonal antibodiesQ68829463
Protein kinase C required for cytotoxic T lymphocyte triggeringQ68831195
Differential expression of the IL-2 receptor subunits, p55 and p75 on various populations of primary peripheral blood mononuclear cellsQ69386256
A new high-yield continuous cell-culture system for lymphokine-activated killer cellsQ69404864
Adoptive chemoimmunotherapy of murine leukemia with helper T lymphocyte clonesQ69809805
Stimulated rat T cell-derived inhibitory factor for cellular DNA synthesis (STIF). I. Isolation and characterizationQ69936820
A new compact and cell dense continuous culture systemQ69965623
Adoptive Immunotherapy of Established Pulmonary Metastases with LAK Cells and Recombinant Interleukin-2Q70224204
Isolation of pure functionally active CD8+ T cells. Positive selection with monoclonal antibodies directly conjugated to monosized magnetic microspheresQ70294369
Cross-linking of the T cell receptor complex with the subset-specific differentiation antigen stimulates interleukin 2 receptor expression in human CD4 and CD8 T cellsQ70336391
In vivo generation of lymphokine-activated killer cells by sensitization with interleukin 2-producing syngeneic T-lymphoma cellsQ70378784
Differential requirements for activation and growth of unprimed cytotoxic and helper T lymphocytesQ72794789
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectimmunotherapyQ1427096
adoptive immunotherapyQ72138716
P304page(s)20-26
P577publication date1992-07-01
P1433published inBritish Journal of CancerQ326309
P1476titleLarge-scale culture system of human CD4+ helper/killer T cells for the application to adoptive tumour immunotherapy
P478volume66

Reverse relations

cites work (P2860)
Q42390176Adoptive tumour immunotherapy using human CD4+ T-cells
Q45859672Artificial capillary culture: expansion and retroviral transduction of CD4+ T-lymphocytes for clinical application
Q55005210Expression of tumor-associated glycoantigen, sialyl Lewis(a), in human head and neck squamous cell carcinoma and its application to tumor immunotherapy.
Q41438696HER-2/neu protein: a target for antigen-specific immunotherapy of human cancer.
Q35157412Phase I Study of Anti-CD3 x Anti-Her2 Bispecific Antibody in Metastatic Castrate Resistant Prostate Cancer Patients.
Q42528693Primary cytotoxicity of SEB-activated human PBMC and separated CD8+ and CD4+ T lymphocytes elicited by two different stimulation protocols
Q46578109Response to the letter from Drs Gold and Osband.