Endogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes

scientific article published on September 2006

Endogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ20060183
P932PMC publication ID1550310
P698PubMed publication ID16719842

P2093author name stringAndreas Lückhoff
Eberhard Jüngling
Maike Warnstedt
Inka Heiner
Jörg Eisfeld
Natalia Radukina
P2860cites workMolecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brainQ22007959
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homologyQ24291275
Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivoQ28203353
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell deathQ28216181
A novel cycling assay for cellular cADP-ribose with nanomolar sensitivityQ28344303
Topology of CD38.Q33941877
Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38.Q34060896
The PARP superfamilyQ34335821
Structure and enzymology of ADP-ribosyl cyclases: conserved enzymes that produce multiple calcium mobilizing metabolitesQ35752802
The calcium signal and neutrophil activation.Q37942212
Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.Q38337070
Determination of intracellular concentrations of the TRPM2 agonist ADP-ribose by reversed-phase HPLC.Q40416133
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channelsQ40439348
Chemotaxis and calcium responses of phagocytes to formyl peptide receptor ligands is differentially regulated by cyclic ADP riboseQ40597235
Response to ADP-ribose by activation of TRPM2 in the CRI-G1 insulinoma cell lineQ40672488
Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD.Q40673306
Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activationQ40677462
Immunocyte Ca2+ influx system mediated by LTRPC2.Q40785446
Novel hydrolysis-resistant analogues of cyclic ADP-ribose: modification of the "northern" ribose and calcium release activityQ44001873
Activation of T cell calcium influx by the second messenger ADP-riboseQ46827120
Characterization of human and mouse TRPM2 genes: identification of a novel N-terminal truncated protein specifically expressed in human striatumQ48150896
Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-riboseQ48308060
Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose.Q53935821
Rates of diffusional exchange between small cells and a measuring patch pipette.Q54389976
Rapid assay of adenine nucleotides or creatine compounds in extracts of cardiac tissue by paired-ion reverse-phase high-performance liquid chromatographyQ71348684
Caspase-mediated proteolysis during apoptosis: insights from apoptotic neutrophilsQ74267781
A noninvasive fluorimetric procedure for measurement of membrane potential. Quantification of the NADPH oxidase-induced depolarization in activated neutrophilsQ78207960
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)225-232
P577publication date2006-09-01
P1433published inBiochemical JournalQ864221
P1476titleEndogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes
P478volume398

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cites work (P2860)
Q46764885A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events
Q34510656A cell permeable NPE caged ADP-ribose for studying TRPM2
Q83227732A single regulator NrtR controls bacterial NAD homeostasis via its acetylation
Q92914225Albumin evokes Ca2+-induced cell oxidative stress and apoptosis through TRPM2 channel in renal collecting duct cells reduced by curcumin
Q36976648Altered functional properties of a TRPM2 variant in Guamanian ALS and PD.
Q52881634Anti-tumor Necrosis Factor Alpha (Infliximab) Attenuates Apoptosis, Oxidative Stress, and Calcium Ion Entry Through Modulation of Cation Channels in Neutrophils of Patients with Ankylosing Spondylitis.
Q44015832Ca2+-dependent induction of TRPM2 currents in hippocampal neurons
Q37901880Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines.
Q33882274Cell surface topology creates high Ca2+ signalling microdomains
Q36615011Cells move when ions and water flow
Q39687155Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8.
Q28584942Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release
Q46256705Different Principles of ADP-Ribose-Mediated Activation and Opposite Roles of the NUDT9 Homology Domain in the TRPM2 Orthologs of Man and Sea Anemone
Q64067828Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR
Q52689030Disruption of transient receptor potential melastatin 2 decreases elastase release and bacterial clearance in neutrophils.
Q99238298Does Cyclic ADP-Ribose (cADPR) Activate the Non-selective Cation Channel TRPM2?
Q46703875Effect of oxidative stress on TRPM2 and TRPC3 channels in B lymphoblast cells in bipolar disorder
Q64084155Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates
Q38916567Functional characterisation of a TRPM2 orthologue from the sea anemone Nematostella vectensis in human cells
Q40043677H2O 2-stimulated Ca2+ influx via TRPM2 is not the sole determinant of subsequent cell death
Q34976995H2O2-induced Ca2+ influx and its inhibition by N-(p-amylcinnamoyl) anthranilic acid in the beta-cells: involvement of TRPM2 channels
Q41923686Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.
Q43247368Inhibitors of TRP channels reveal stimulus-dependent differential activation of Ca2+ influx pathways in human neutrophil granulocytes
Q37182741Intracellular calcium activates TRPM2 and its alternative spliced isoforms
Q30402082Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
Q39108444Lys1110 of TRPM2 is critical for channel activation.
Q58176165Mitochondrial Dysfunction Induced by a Cytotoxic Adenine Dinucleotide Produced by ADP-ribosyl Cyclases from cADPR
Q33590332Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity
Q90308515Molecular Regulations and Functions of the Transient Receptor Potential Channels of the Islets of Langerhans and Insulinoma Cells
Q37999843Molecular role of catalase on oxidative stress-induced Ca(2+) signaling and TRP cation channel activation in nervous system
Q36846822New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose
Q33756984Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates Inflammation
Q34498406Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels
Q28396273Reactive oxygen species in inflammation and tissue injury
Q33525390Reference genes for normalising gene expression data in collagenase-induced rat intracerebral haemorrhage
Q36296075Regulation of TRPM2 by extra- and intracellular calcium.
Q37179987Regulation of superoxide production in neutrophils: role of calcium influx
Q50357094Role of H(2)O(2)-activated TRPM2 calcium channel in oxidant-induced endothelial injury.
Q38110508Roles of ion transport in control of cell motility
Q90646893Selective profiling of N- and C-terminal nucleotide-binding sites in a TRPM2 channel
Q59000891Signalling in Neutrophils: A Retro Look
Q27656441Structure and Function of an ADP-Ribose-Dependent Transcriptional Regulator of NAD Metabolism
Q39969317Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils
Q58791928TRP Channels in the Sensation of Heat
Q53836690TRPM2 and warmth sensation.
Q37817844TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
Q83931929TRPM2 channel membrane currents in primary rat megakaryocytes were activated by the agonist ADP-ribose but not oxidative stress
Q37850688TRPM2, calcium and neurodegenerative diseases.
Q52578572TRPM2: a candidate therapeutic target for treating neurological diseases.
Q36015320TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD?
Q28067161Targeting TRPM2 in ROS-Coupled Diseases
Q39965490The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes
Q38043290The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation
Q88538598The function of TRP channels in neutrophil granulocytes
Q52354765The role of TRPM2 channels in neurons, glial cells and the blood-brain barrier in cerebral ischemia and hypoxia.
Q48263089Transient receptor potential melastatin 2 expression is increased following experimental traumatic brain injury in rats.

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