Moringa oleifera Flower Extract Suppresses the Activation of Inflammatory Mediators in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages via NF-κB Pathway

scientific article published on 2 November 2015

Moringa oleifera Flower Extract Suppresses the Activation of Inflammatory Mediators in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages via NF-κB Pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2015/720171
P932PMC publication ID4644847
P698PubMed publication ID26609199
P5875ResearchGate publication ID283974731

P2093author name stringPalanisamy Arulselvan
Sharida Fakurazi
Govindarajan Karthivashan
Woan Sean Tan
P2860cites workAnti-inflammatory effects of flavonoids [etc.]Q21342966
Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammationQ24564394
Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidantsQ26341684
Nitric oxide: physiology, pathophysiology, and pharmacologyQ26778243
Role of oxidants in NF-kappa B activation and TNF-alpha gene transcription induced by hypoxia and endotoxinQ28139739
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Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway.Q50774292
Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages.Q53503581
Identification of Bioactive Candidate Compounds Responsible for Oxidative Challenge from Hydro-Ethanolic Extract ofMoringa oleiferaLeavesQ63285756
Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial culturesQ74179811
Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide andQ74587899
Both Erk and p38 kinases are necessary for cytokine gene transcriptionQ74665369
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Moringa oleifera hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimental rats through their antioxidant natureQ84559593
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signalingQ28593045
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Chromene suppresses the activation of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 cellsQ31152386
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NF-kappaB as a therapeutic target in chronic inflammation: recent advancesQ34080585
LPS induction of gene expression in human monocytesQ34189313
Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia: A Review.Q34259995
Nitric oxide in immunity and inflammationQ34342605
Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophagesQ34501281
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Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranesQ36779662
Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microgliaQ38452714
Anti-inflammatory effects of calcium citrate in RAW 264.7cells via suppression of NF-κB activationQ38936857
Downregulation of pro-inflammatory mediators by a water extract of Schisandra chinensis (Turcz.) Baill fruit in lipopolysaccharide-stimulated RAW 264.7 macrophage cellsQ39150026
Moringa oleifera pod inhibits inflammatory mediator production by lipopolysaccharide-stimulated RAW 264.7 murine macrophage cell linesQ39277972
Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruitsQ39671450
The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cellsQ40191280
Effect of Moringa oleifera flower extract on larval trypsin and acetylcholinesterase activities in Aedes aegyptiQ40294116
Janus kinase 2 is involved in lipopolysaccharide-induced activation of macrophagesQ40657235
Tumor necrosis factors: developments during the last decade.Q41020160
Competing role of bioactive constituents in Moringa oleifera extract and conventional nutrition feed on the performance of Cobb 500 broilersQ42180691
Trypsin inhibitor from Moringa oleifera flowers interferes with survival and development of Aedes aegypti larvae and kills bacteria inhabitant of larvae midgutQ42998023
Therapeutic potential of Moringa oleifera extracts against acetaminophen-induced hepatotoxicity in ratsQ43515878
An oxygenase inhibitor study in Solanum lycopersicum combined with metabolite profiling analysis revealed a potent peroxygenase inactivatorQ43781641
Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro.Q44075619
Inflammatory bowel disease: a model of chronic inflammation-induced cancerQ46060753
Characterization of flavonoids and phenolic acids in Myrcia bella Cambess. using FIA-ESI-IT-MS(n) and HPLC-PAD-ESI-IT-MS combined with NMR.Q47737826
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectmoringaQ234193
NF-κBQ411114
lipopolysaccharideQ421804
P304page(s)720171
P577publication date2015-11-02
P1433published inMediators of InflammationQ2144494
P1476titleMoringa oleifera Flower Extract Suppresses the Activation of Inflammatory Mediators in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages via NF-κB Pathway
P478volume2015

Reverse relations

cites work (P2860)
Q51347341Anti-Inflammatory Potential of Ethyl Acetate Fraction of Moringa oleifera in Downregulating the NF-κB Signaling Pathway in Lipopolysaccharide-Stimulated Macrophages.
Q61446733Improvement of diabetic wound healing by topical application of Vicenin-2 hydrocolloid film on Sprague Dawley rats
Q95853813In Vitro Macrophage Nitric Oxide and Interleukin-1 Beta Suppression by Moringa peregrina Seed
Q92256590Investigation of medicinal plants traditionally used as dietary supplements: A review on Moringa oleifera
Q52674868Moringa Genus: A Review of Phytochemistry and Pharmacology.
Q55259388Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments.
Q37216548Probing Regenerative Potential of Moringa oleifera Aqueous Extracts Using In vitro Cellular Assays
Q28079468Role of Antioxidants and Natural Products in Inflammation
Q64890008Solvent Extraction and Identification of Active Anticariogenic Metabolites in Piper cubeba L. through ¹H-NMR-Based Metabolomics Approach.
Q58805779Suppression of Proinflammatory Cytokines and Mediators in LPS-Induced RAW 264.7 Macrophages by Stem Extract of via the Inhibition of the NF-B Pathway
Q39410506Wound healing properties of ethyl acetate fraction of Moringa oleifera in normal human dermal fibroblasts

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