Inhibition of mTOR Prevents ROS Production Initiated by Ethidium Bromide-Induced Mitochondrial DNA Depletion

scientific article

Inhibition of mTOR Prevents ROS Production Initiated by Ethidium Bromide-Induced Mitochondrial DNA Depletion is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FENDO.2014.00122
P932PMC publication ID4109433
P698PubMed publication ID25104948
P5875ResearchGate publication ID264629043

P2093author name stringChristian Sell
Ashley Azar
Timothy Nacarelli
P2860cites workPINK1 is selectively stabilized on impaired mitochondria to activate ParkinQ21145802
Guidelines for the use and interpretation of assays for monitoring autophagyQ21996341
Premature ageing in mice expressing defective mitochondrial DNA polymeraseQ24294365
Characterization of the human heart mitochondrial proteomeQ24294999
The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutationsQ24297798
Rapamycin fed late in life extends lifespan in genetically heterogeneous miceQ24647805
A complex interplay between Akt, TSC2 and the two mTOR complexesQ24655791
Mitochondrial DNA depletion syndromes: review and updates of genetic basis, manifestations, and therapeutic optionsQ26865135
Sequence and organization of the human mitochondrial genomeQ27860659
Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restrictionQ28304066
The thiazolidinedione pioglitazone alters mitochondrial function in human neuron-like cellsQ30443272
Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylationQ31809728
Long-term IGF-I exposure decreases autophagy and cell viabilityQ33689399
Abnormal DNA patterns in animal mitochondria: ethidium bromide-induced breakdown of closed circular DNA and conditions leading to oligomer accumulationQ33711074
mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndromeQ33749391
Mitochondrial genome maintenance in health and disease.Q33821051
Modulation of mitochondrial transcription in response to mtDNA depletion and repletion in HeLa cellsQ33833886
Analysis of the PINK1 gene in a large cohort of cases with Parkinson diseaseQ34376115
In situ localization of mitochondrial DNA replication in intact mammalian cellsQ36256880
Nuclear and mitochondrial deoxyribonucleic acid replication during mitosis in Saccharomyces cerevisiaeQ36605484
Mitochondrial DNA-deficient models and agingQ36802140
Proteome profile of functional mitochondria from human skeletal muscle using one-dimensional gel electrophoresis and HPLC-ESI-MS/MS.Q37415308
Mitochondrial DNA mutations and human diseaseQ37599004
Diagnosis of mitochondrial myopathiesQ38126245
Adaptive responses to mitochondrial dysfunction in the rho degrees Namalwa cellQ38323070
Mitochondrial dysfunction contributes to oncogene-induced senescence.Q39837656
Ethidium bromide-induced loss of mitochondrial DNA from primary chicken embryo fibroblastsQ40666227
A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1.Q40875073
Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblastsQ41434730
DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determinationQ41953580
The effect of ethidium bromide and chloramphenicol on mitochondrial biogenesis in primary human fibroblasts.Q42717404
Replication of mitochondrial DNA occurs throughout the mitochondria of cultured human cellsQ44563858
Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycleQ44625940
Establishment of human cell lines lacking mitochondrial DNA.Q45975304
Mitochondria-targeting sequence, a multi-role sorting sequence recognized at all steps of protein import into mitochondriaQ48034307
EtBr-induced selective degradation of mitochondria occurs via autophagy.Q50857191
Differential effects of ethidium bromide on mitochondrial and nuclear DNA synthesis in vivo in cultured mammalian cells.Q53603375
Mitochondrial DNA in mortal and immortal human cells. Genome number, integrity, and methylationQ70153945
Mitochondrial-associated 4 s RNA synthesis inhibition by ethidium bromideQ71255996
Selective inhibition of the synthesis of mitochondria-associated RNA by ethidium bromideQ72489956
Insulin-like growth factor I-mediated degradation of insulin receptor substrate-1 is inhibited by epidermal growth factor in prostate epithelial cellsQ73794088
P921main subjectmitochondrial DNAQ27075
P304page(s)122
P577publication date2014-07-24
P1433published inFrontiers in EndocrinologyQ27723680
P1476titleInhibition of mTOR Prevents ROS Production Initiated by Ethidium Bromide-Induced Mitochondrial DNA Depletion
P478volume5

Reverse relations

cites work (P2860)
Q38275627Aberrant mTOR activation in senescence and aging: A mitochondrial stress response?
Q37618066Autophagic flux, a possible mechanism for delayed gentamicin-induced ototoxicity
Q37061263CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, β-Catenin, and hTERT Activities
Q46243045Effects of Resveratrol, Lovastatin and the mTOR-Inhibitor RAD-001 on Insulin-Induced Genomic Damage In Vitro.
Q88565251Fluorofenidone inhibits UV-A induced senescence in human dermal fibroblasts via the mammalian target of rapamycin-dependent SIRT1 pathway
Q47600497Mitochondrial DNA content is associated with ploidy status, maternal age, and oocyte maturation methods in mouse blastocysts.
Q89697734Protective Effect of L-Hexaguluroic Acid Hexasodium Salt on UVA-Induced Photo-Aging in HaCaT Cells
Q41092652Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFκB pathways in autophagy- and p62-dependent manners
Q46302218Reactive oxygen species (ROS) are a key determinant of cancer's metabolic phenotype

Search more.