| scholarly article | Q13442814 |
| P2093 | author name string | Y Yang | |
| J Qin | |||
| B R Williams | |||
| S Nanduri | |||
| B W Carpick | |||
| P2860 | cites work | Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon | Q24301655 |
| Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways | Q24532129 | ||
| Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo | Q24563365 | ||
| Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A | Q27660274 | ||
| NMR solution structure of a dsRNA binding domain from Drosophila staufen protein reveals homology to the N-terminal domain of ribosomal protein S5 | Q27729790 | ||
| NMRPipe: a multidimensional spectral processing system based on UNIX pipes | Q27860859 | ||
| The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR | Q28306498 | ||
| The impact of direct refinement against 13C alpha and 13C beta chemical shifts on protein structure determination by NMR. | Q30419175 | ||
| The impact of direct refinement against three-bond HN-C alpha H coupling constants on protein structure determination by NMR. | Q30420442 | ||
| Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR. | Q30468875 | ||
| Double-stranded RNA-independent dimerization of interferon-induced protein kinase PKR and inhibition of dimerization by the cellular P58IPK inhibitor | Q33786424 | ||
| Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB | Q33886023 | ||
| 1H-NMR stereospecific assignments by conformational data-base searches | Q33930275 | ||
| Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2 | Q33937662 | ||
| The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo | Q33965039 | ||
| Structural requirements of double-stranded RNA for the activation of 2‘,5‘-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells | Q34221795 | ||
| Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B. | Q35566028 | ||
| The respective roles of the protein kinase and pppA2' p5' A2' p5 A-activated endonuclease in the inhibition of protein synthesis by double stranded RNA in rabbit reticulocyte lysates | Q35751667 | ||
| A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis | Q36084388 | ||
| Determination of three-dimensional structures of proteins from interproton distance data by hybrid distance geometry-dynamical simulated annealing calculations | Q36449550 | ||
| Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae | Q36566913 | ||
| Double-stranded RNA-dependent protein kinase and 2-5A system are both activated in interferon-treated, encephalomyocarditis virus-infected HeLa cells | Q36902455 | ||
| Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells | Q37621199 | ||
| Role of the amino-terminal residues of the interferon-induced protein kinase in its activation by double-stranded RNA and heparin | Q38306294 | ||
| Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties | Q38352344 | ||
| Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR). | Q38362637 | ||
| Structure of the dsRNA binding domain of E. coli RNase III. | Q40788883 | ||
| Field gradient techniques in NMR spectroscopy | Q40953857 | ||
| Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q- associated leukemias | Q41206668 | ||
| Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase | Q41602853 | ||
| PKR--a protein kinase regulated by double-stranded RNA. | Q41647401 | ||
| Interactions between double-stranded RNA regulators and the protein kinase DAI | Q41845602 | ||
| Interactions between the double-stranded RNA binding motif and RNA: definition of the binding site for the interferon-induced protein kinase DAI (PKR) on adenovirus VA RNA. | Q42089572 | ||
| Functional characterization of the RNA-binding domain and motif of the double-stranded RNA-dependent protein kinase DAI (PKR). | Q42686037 | ||
| Mutational analysis of the double-stranded RNA (dsRNA) binding domain of the dsRNA-activated protein kinase, PKR. | Q42830084 | ||
| The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates | Q43838226 | ||
| Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA. | Q43860103 | ||
| Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase | Q44081848 | ||
| Identification of IL-6 as a T cell-derived factor that enhances the proliferative response of thymocytes to IL-4 and phorbol myristate acetate | Q44424885 | ||
| Blockage of NF-kappa B signaling by selective ablation of an mRNA target by 2-5A antisense chimeras | Q58666576 | ||
| Two RNA-binding motifs in the double-stranded RNA-activated protein kinase, DAI | Q64377967 | ||
| The binding of double-stranded RNA and adenovirus VAI RNA to the interferon-induced protein kinase | Q64379280 | ||
| A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR. | Q64970986 | ||
| Two interferon-induced proteins are involved in the protein kinase complex dependent on double-stranded RNA | Q68949590 | ||
| Mechanism of interferon action. Increased phosphorylation of protein synthesis initiation factor eIF-2 alpha in interferon-treated, reovirus-infected mouse L929 fibroblasts in vitro and in vivo | Q70648583 | ||
| Ribosome targeting of PKR is mediated by two double-stranded RNA-binding domains and facilitates in vivo phosphorylation of eukaryotic initiation factor-2 | Q73363093 | ||
| P433 | issue | 18 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 5458-5465 | |
| P577 | publication date | 1998-09-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation | |
| P478 | volume | 17 |
| Q33701022 | A Nonpolycationic Fully Proteinaceous Multiagent System for Potent Targeted Delivery of siRNA. |
| Q42834260 | A cell-permeable peptide inhibits activation of PKR and enhances cell proliferation |
| Q40430436 | A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR. |
| Q24536298 | A method to find tissue-specific novel sites of selective adenosine deamination |
| Q41062660 | A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III. |
| Q27636820 | A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III. |
| Q92767123 | A ribonucleoprotein octamer for targeted siRNA delivery |
| Q37013316 | A specific aptamer-cell penetrating peptides complex delivered siRNA efficiently and suppressed prostate tumor growth in vivo |
| Q38311422 | A universal protein tag for delivery of SiRNA-aptamer chimeras |
| Q36695833 | Activation of PKR: an open and shut case? |
| Q35160599 | An ADAR that edits transcripts encoding ion channel subunits functions as a dimer. |
| Q41994382 | An extra double-stranded RNA binding domain confers high activity to a squid RNA editing enzyme. |
| Q34079750 | Analysis of PKR activation using analytical ultracentrifugation |
| Q37144662 | Analysis of PKR structure by small-angle scattering |
| Q38338364 | Analysis of PKR-RNA interactions by sedimentation velocity |
| Q28141516 | Analysis of a binding difference between the two dsRNA-binding domains in TRBP reveals the modular function of a KR-helix motif |
| Q36390621 | Analysis of high-affinity binding of protein kinase R to double-stranded RNA |
| Q41900049 | Analysis of monomeric and dimeric phosphorylated forms of protein kinase R. |
| Q33359465 | Andes virus nucleocapsid protein interrupts protein kinase R dimerization to counteract host interference in viral protein synthesis |
| Q37692314 | Auto-phosphorylation Represses Protein Kinase R Activity |
| Q22010847 | Autoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activity |
| Q43597902 | Binding of double-stranded RNA to protein kinase PKR is required for dimerization and promotes critical autophosphorylation events in the activation loop. |
| Q34254661 | Binding site multiplicity with fatty acid ligands: implications for the regulation of PKR kinase autophosphorylation with palmitate |
| Q37398875 | Biochemical analysis of PKR activation by PACT. |
| Q46905275 | Biophysical and biochemical investigations of dsRNA-activated kinase PKR. |
| Q54196043 | Both N-terminal catalytic and C-terminal RNA binding domain contribute to substrate specificity and cleavage site selection of RNase III. |
| Q33835582 | Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model |
| Q34046869 | Building better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptive immunity |
| Q35817098 | Chimeric double-stranded RNA-specific adenosine deaminase ADAR1 proteins reveal functional selectivity of double-stranded RNA-binding domains from ADAR1 and protein kinase PKR. |
| Q42671370 | Comparative analysis and molecular characterization of a gene BANF1 encoded a DNA-binding protein during mitosis from the Giant Panda and Black Bear |
| Q47106289 | Conserved asymmetry underpins homodimerization of Dicer-associated double-stranded RNA-binding proteins |
| Q27652209 | Crystal Structure of the Avian Reovirus Inner Capsid Protein A |
| Q24337755 | Crystal structure of human DGCR8 core |
| Q27636675 | Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage |
| Q42053304 | Determination of preferential binding sites for anti-dsRNA antibodies on double-stranded RNA by scanning force microscopy |
| Q36174842 | Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering |
| Q38335714 | Dissecting the roles of TRBP and PACT in double-stranded RNA recognition and processing of noncoding RNAs |
| Q34017488 | DomSVR: domain boundary prediction with support vector regression from sequence information alone |
| Q37652771 | Domain interactions in adenovirus VAI RNA mediate high-affinity PKR binding |
| Q37312236 | Domain stabilities in protein kinase R (PKR): evidence for weak interdomain interactions |
| Q33321981 | Double-stranded RNA-activated protein kinase PKR of fishes and amphibians: varying the number of double-stranded RNA binding domains and lineage-specific duplications |
| Q36006780 | Duplex RNA-binding enzymes: headliners from neurobiology, virology, and development |
| Q43181153 | Dynamic origins of differential RNA binding function in two dsRBDs from the miRNA "microprocessor" complex |
| Q36002507 | Dynamic profiling of double-stranded RNA binding proteins |
| Q34648134 | Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling |
| Q38328212 | Editing of glutamate receptor subunit B pre-mRNA by splice-site variants of interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1. |
| Q28208397 | Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR |
| Q39864398 | Enterovirus 71 induces dsRNA/PKR-dependent cytoplasmic redistribution of GRP78/BiP to promote viral replication |
| Q39745125 | Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis |
| Q40511804 | Exogenous siRNA mediates sequence-independent gene suppression by signaling through toll-like receptor 3. |
| Q40132236 | Filovirus Strategies to Escape Antiviral Responses |
| Q33661005 | Function, mechanism and regulation of bacterial ribonucleases |
| Q31778073 | Functional characterization of and cooperation between the double-stranded RNA-binding motifs of the protein kinase PKR. |
| Q41728104 | Functional redundancy in the nonspecific RNA binding domain of a class I tRNA synthetase |
| Q37271103 | Genome-wide analysis of Staufen-associated mRNAs identifies secondary structures that confer target specificity |
| Q35706998 | Heparin activates PKR by inducing dimerization |
| Q33836081 | Hepatitis C virus envelope protein E2 does not inhibit PKR by simple competition with autophosphorylation sites in the RNA-binding domain |
| Q37672476 | Identification of the heparin-binding domains of the interferon-induced protein kinase, PKR |
| Q24672548 | Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action |
| Q47425918 | Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition |
| Q24538727 | Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein |
| Q43677683 | Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2alpha (eIF2alpha). |
| Q64229581 | Innate Immune Responses to Avian Influenza Viruses in Ducks and Chickens |
| Q41968360 | Interaction of PKR with single-stranded RNA |
| Q24304341 | Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR |
| Q36557550 | Interferon action and the double-stranded RNA-dependent enzymes ADAR1 adenosine deaminase and PKR protein kinase |
| Q27486790 | Interferon-inducible antiviral effectors |
| Q27026181 | Interplay between interferon-mediated innate immunity and porcine reproductive and respiratory syndrome virus |
| Q27675338 | Intrinsic Dynamics of an Extended Hydrophobic Core in the S. cerevisiae RNase III dsRBD Contributes to Recognition of Specific RNA Binding Sites |
| Q34102905 | Involvement of activation of PKR in HBx-siRNA-mediated innate immune effects on HBV inhibition |
| Q42739644 | MD simulations of the dsRBP DGCR8 reveal correlated motions that may aid pri-miRNA binding |
| Q34162276 | MRNA stability and the control of gene expression: implications for human disease |
| Q42128194 | Magnesium-dependent interaction of PKR with adenovirus VAI. |
| Q39746661 | Mapping of the auto-inhibitory interactions of protein kinase R by nuclear magnetic resonance. |
| Q37843467 | MeCP2: structure and function |
| Q36943661 | Mechanism of PKR Activation by dsRNA. |
| Q39417308 | Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2). |
| Q28211625 | Minihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3 |
| Q24551001 | Modular structure of PACT: distinct domains for binding and activating PKR |
| Q24550949 | Molecular basis for PKR activation by PACT or dsRNA |
| Q47141103 | Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference |
| Q46581088 | Molecular framework for the activation of RNA-dependent protein kinase |
| Q24534331 | Molecular mapping of the determinants involved in human Staufen-ribosome association |
| Q34561217 | Molecular mechanism by which palmitate inhibits PKR autophosphorylation. |
| Q26782034 | New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins |
| Q35819919 | New insights about ORF1 coding regions support the proposition of a new genus comprising arthropod viruses in the family Totiviridae |
| Q37141946 | ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases |
| Q38336865 | Oligomerization activity of a double-stranded RNA-binding domain |
| Q35944970 | PKR Transduces MDA5-Dependent Signals for Type I IFN Induction |
| Q30398450 | PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load |
| Q28137774 | PKR; a sentinel kinase for cellular stress |
| Q35543791 | Phylogenetics and functions of the double-stranded RNA-binding motif: a genomic survey. |
| Q30416801 | Prediction of a novel RNA binding domain in crocodilepox Zimbabwe Gene 157. |
| Q28505817 | Proapoptotic protein PACT is expressed at high levels in colonic epithelial cells in mice |
| Q24298263 | Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation |
| Q64101574 | Protein-based vehicles for biomimetic RNAi delivery |
| Q33899394 | Proteins binding to duplexed RNA: one motif, multiple functions |
| Q37389973 | RNA dimerization promotes PKR dimerization and activation |
| Q24679593 | RNA editing by adenosine deaminases that act on RNA |
| Q27621605 | RNA recognition by a Staufen double-stranded RNA-binding domain |
| Q27023888 | RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence |
| Q33684328 | RNA-protein complexes |
| Q34749879 | RNA-protein interactions |
| Q34141716 | Recognition between flexible protein molecules: induced and assisted folding |
| Q42146692 | Recognition of viral RNA stem-loops by the tandem double-stranded RNA binding domains of PKR. |
| Q40406915 | Regulation of PKR by RNA: formation of active and inactive dimers |
| Q34786169 | Regulation of innate immunity through RNA structure and the protein kinase PKR. |
| Q29041137 | Ribonuclease III: new sense from nuisance |
| Q27639870 | Ribosome-associated factor Y adopts a fold resembling a double-stranded RNA binding domain scaffold |
| Q41041212 | Role of the Interdomain Linker in RNA-Activated Protein Kinase Activation |
| Q34304805 | Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs |
| Q39448377 | Sensitivity of an epstein-barr virus-positive tumor line, Daudi, to alpha interferon correlates with expression of a GC-rich viral transcript |
| Q73187005 | Sequence dependence of substrate recognition and cleavage by yeast RNase III |
| Q83145000 | Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: a central role for 2'-hydroxyl uridines in immune responses |
| Q33630916 | Site-specific modification and RNA crosslinking of the RNA-binding domain of PKR. |
| Q44784430 | Site-specific modification of Epstein-Barr virus-encoded RNA 1 with N2-benzylguanosine limits the binding sites occupied by PKR. |
| Q54295799 | Six-cell penetrating peptide-based fusion proteins for siRNA delivery. |
| Q27636825 | Solution structure of conserved AGNN tetraloops: insights into Rnt1p RNA processing |
| Q27678235 | Solution structures of the double-stranded RNA-binding domains from RNA helicase A |
| Q36526187 | Specificity of the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR for double-stranded RNA: insights from thermodynamics and small-angle X-ray scattering. |
| Q35837330 | Straightening of bulged RNA by the double-stranded RNA-binding domain from the protein kinase PKR. |
| Q47551643 | Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival. |
| Q37499514 | Structural and functional modules in RNA interference |
| Q27676050 | Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9) |
| Q28074726 | Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering, and computational methods |
| Q24534133 | Structure and interactions of the translation initiation factor eIF1 |
| Q27687611 | Structure of RDE-4 dsRBDs and mutational studies provide insights into dsRNA recognition in the Caenorhabditis elegans RNAi pathway |
| Q27670743 | Structure of a Yeast RNase III dsRBD Complex with a Noncanonical RNA Substrate Provides New Insights into Binding Specificity of dsRBDs |
| Q27630251 | Structure of the reovirus outer capsid and dsRNA-binding protein sigma3 at 1.8 A resolution |
| Q33733307 | Substrate recognition and specificity of double-stranded RNA binding proteins |
| Q41673013 | Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis |
| Q24338458 | TRAF family proteins link PKR with NF-kappa B activation |
| Q36123983 | Targeting polyIC to EGFR over-expressing cells using a dsRNA binding protein domain tethered to EGF. |
| Q26858833 | The ADAR protein family |
| Q38316109 | The N-terminal domain that distinguishes yeast from bacterial RNase III contains a dimerization signal required for efficient double-stranded RNA cleavage |
| Q40630415 | The Orf virus E3L homologue is able to complement deletion of the vaccinia virus E3L gene in vitro but not in vivo |
| Q24320118 | The RNA-binding region of human TRBP interacts with microRNA precursors through two independent domains |
| Q36301254 | The Regulatory and Kinase Domains but Not the Interdomain Linker Determine Human Double-stranded RNA-activated Kinase (PKR) Sensitivity to Inhibition by Viral Non-coding RNAs |
| Q33758060 | The binding site of the RNA-dependent protein kinase (PKR) on EBER1 RNA from Epstein-Barr virus |
| Q40167543 | The caspase-generated fragments of PKR cooperate to activate full-length PKR and inhibit translation |
| Q35968493 | The double-stranded-RNA-binding motif: interference and much more |
| Q34598589 | The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway |
| Q31129671 | The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen |
| Q64076950 | The search for a PKR code-differential regulation of protein kinase R activity by diverse RNA and protein regulators |
| Q27640803 | The structure of the zinc finger domain from human splicing factor ZNF265 fold |
| Q33184245 | The ubiquitous nature of RNA chaperone proteins |
| Q28573755 | Two rat brain staufen isoforms differentially bind RNA |
| Q38181142 | Type I Interferon at the Interface of Antiviral Immunity and Immune Regulation: The Curious Case of HIV-1. |
| Q24535918 | Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase |
| Q34034965 | Unactivated PKR exists in an open conformation capable of binding nucleotides |
| Q51825443 | Uncovering the PKR pathway's potential for treatment of tumors. |
| Q37008351 | Viral dsRNA inhibitors prevent self-association and autophosphorylation of PKR. |
| Q36926779 | Viral stress-inducible genes. |
| Q36503722 | Virus counterdefense: diverse strategies for evading the RNA-silencing immunity |
| Q35528928 | West Nile virus infection does not induce PKR activation in rodent cells |
| Q42665877 | cDNA, genomic sequence cloning, and overexpression of EIF1 from the giant panda (Ailuropoda Melanoleuca) and the black bear (Ursus Thibetanus Mupinensis). |
| Q36119180 | dsRBM1 and a proline-rich domain of RNA helicase A can form a composite binder to recognize a specific dsDNA |
| Q36432681 | dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection |
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