NK cells and gamma interferon coordinate the formation and function of hepatic granulomas in mice infected with the Francisella tularensis live vaccine strain

scientific article published on 28 January 2008

NK cells and gamma interferon coordinate the formation and function of hepatic granulomas in mice infected with the Francisella tularensis live vaccine strain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00745-07
P932PMC publication ID2292861
P698PubMed publication ID18227174

P2093author name stringHung-Wen Yeh
Michael J Parmely
David M Pinson
Joyce Slusser
Kee-Jun Kim
Sirosh M Bokhari
P2860cites workImmunologic consequences of Francisella tularensis live vaccine strain infection: role of the innate immune response in infection and immunityQ40278110
Role of macrophage scavenger receptors in response to Listeria monocytogenes infection in miceQ42048523
Different host defences are required to protect mice from primary systemic vs pulmonary infection with the facultative intracellular bacterial pathogen, Francisella tularensis LVS.Q43215876
Susceptibility of immunodeficient mice to aerosol and systemic infection with virulent strains of Francisella tularensisQ44878064
Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient miceQ45040266
The requirement for gamma interferon in resistance of mice to experimental tularemiaQ45882668
Early activation of NK cells after lung infection with the intracellular bacterium, Francisella tularensis LVS.Q47789471
Experimental visceral leishmaniasis: role of endogenous IFN-gamma in host defense and tissue granulomatous response.Q54338844
Seventeen-colour flow cytometry: unravelling the immune systemQ62577376
Experimental tularemia in mice challenged by aerosol or intradermally with virulent strains of Francisella tularensis: bacteriologic and histopathologic studiesQ73355869
Identification of transposon insertion mutants of Francisella tularensis tularensis strain Schu S4 deficient in intracellular replication in the hepatic cell line HepG2.Q30441155
Beyond six colors: a new era in flow cytometryQ30878516
Intranasal interleukin-12 treatment for protection against respiratory infection with the Francisella tularensis live vaccine strain.Q33769426
Redox imbalance differentially inhibits lipopolysaccharide-induced macrophage activation in the mouse liver.Q34002203
TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infectionQ34125021
Tissue granuloma structure-function in experimental visceral leishmaniasisQ34434760
T-cell-independent resistance to infection and generation of immunity to Francisella tularensis.Q34525813
Gamma Interferon Production by Hepatic NK T Cells during Escherichia coli Infection Is Resistant to the Inhibitory Effects of Oxidative StressQ34931790
In situ study of abundant expression of proinflammatory chemokines and cytokines in pulmonary granulomas that develop in cynomolgus macaques experimentally infected with Mycobacterium tuberculosisQ34942057
Role of CCR4 ligands, CCL17 and CCL22, during Schistosoma mansoni egg-induced pulmonary granuloma formation in miceQ35103255
Mac-1+ cells are the predominant subset in the early hepatic lesions of mice infected with Francisella tularensisQ35220421
Minimal requirements for murine resistance to infection with Francisella tularensis LVS.Q35512763
Coactivating signals for the hepatic lymphocyte gamma interferon response to Francisella tularensisQ35689466
Effect of C-C chemokine receptor 2 (CCR2) knockout on type-2 (schistosomal antigen-elicited) pulmonary granuloma formation: analysis of cellular recruitment and cytokine responsesQ35786914
Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guérin and subsequent challenge with lipopolysaccharide.Q36362408
Pathological diagnosis of granulomatous lung disease: a reviewQ36719728
In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodiesQ36953816
Live vaccine strain of Francisella tularensis: infection and immunity in miceQ36967503
Characterization of the Histoplasma capsulatum-induced granulomaQ37357512
Histologic and molecular diagnosis of tularemia: a potential bioterrorism agent endemic to North AmericaQ38448652
Early pathogenesis of infection in the liver with the facultative intracellular bacteria Listeria monocytogenes, Francisella tularensis, and Salmonella typhimurium involves lysis of infected hepatocytes by leukocytesQ40152524
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectFrancisella tularensisQ1003460
attenuated vaccineQ1810913
P304page(s)1379-1389
P577publication date2008-01-28
P1433published inInfection and ImmunityQ6029193
P1476titleNK cells and gamma interferon coordinate the formation and function of hepatic granulomas in mice infected with the Francisella tularensis live vaccine strain
P478volume76

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cites work (P2860)
Q30010211A LysM and SH3-domain containing region of the Listeria monocytogenes p60 protein stimulates accessory cells to promote activation of host NK cells
Q35348877A MyD88-dependent IFNγR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge
Q40179059A Novel In Vitro Human Granuloma Model of Sarcoidosis and Latent TB Infection
Q35887475A human macrophage-hepatocyte co-culture model for comparative studies of infection and replication of Francisella tularensis LVS strain and subspecies holarctica and mediasiatica.
Q34740339Antibodies contribute to effective vaccination against respiratory infection by type A Francisella tularensis strains
Q50980823Attenuation of experimental asthma by mycobacterial protein combined with CpG requires a TLR9-dependent IFN-γ-CCR2 signalling circuit.
Q28675489FeoB-mediated uptake of iron by Francisella tularensis
Q38909303Francisella Inflammasomes: Integrated Responses to a Cytosolic Stealth Bacterium.
Q33877062Francisella tularensis DeltapyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in vivo
Q37410379Francisella tularensis induces extensive caspase-3 activation and apoptotic cell death in the tissues of infected mice
Q34729832Francisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responses
Q37622909Francisella virulence: significant advances, ongoing challenges and unmet needs
Q37075498Host immune response and acute disease in a zebrafish model of Francisella pathogenesis
Q37287818Humoral and cell-mediated immunity to the intracellular pathogen Francisella tularensis.
Q34562654IKKβ in myeloid cells controls the host response to lethal and sublethal Francisella tularensis LVS infection
Q37891779Immunity to Francisella
Q36045043Investigating the Role of TNF-α and IFN-γ Activation on the Dynamics of iNOS Gene Expression in LPS Stimulated Macrophages
Q35063629Morphine enhances Tat-induced activation in murine microglia.
Q37218211MyD88-dependent signaling prolongs survival and reduces bacterial burden during pulmonary infection with virulent Francisella tularensis
Q36018212Perforin- and granzyme-mediated cytotoxic effector functions are essential for protection against Francisella tularensis following vaccination by the defined F. tularensis subsp. novicida ΔfopC vaccine strain
Q36156031Phenotypic, morphological, and functional heterogeneity of splenic immature myeloid cells in the host response to tularemia
Q37441214Programmed cell death and the pathogenesis of tissue injury induced by type A Francisella tularensis
Q33871500Role of NK cells in host defense against pulmonary type A Francisella tularensis infection
Q37191318T cells from lungs and livers of Francisella tularensis-immune mice control the growth of intracellular bacteria
Q36908692Tularemia vaccine development: paralysis or progress?
Q37364640Vaccination with a defined Francisella tularensis subsp. novicida pathogenicity island mutant (DeltaiglB) induces protective immunity against homotypic and heterotypic challenge

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