DNA damage response pathway and replication fork stress during oligonucleotide directed gene editing

scientific article published on 3 April 2012

DNA damage response pathway and replication fork stress during oligonucleotide directed gene editing is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MTNA.2012.9
P932PMC publication ID3381643
P698PubMed publication ID23343929
P5875ResearchGate publication ID235366632

P2093author name stringBryan Strouse
Eric B Kmiec
Melissa Bonner
Paula Livingston
Mindy Applegate
P2860cites workImplications of cell cycle progression on functional sequence correction by short single-stranded DNA oligonucleotidesQ45240563
Single-strand DNA-mediated targeted mutagenesis of genomic DNA in early mouse embryos is stimulated by Rad51/54 and by Ku70/86 inhibitionQ45873660
Use of internally nuclease-protected single-strand DNA oligonucleotides and silencing of the mismatch repair protein, MSH2, enhances the replication of corrected cells following gene editingQ46156951
Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide endsQ46605440
DNA replication, cell cycle progression and the targeted gene repair reaction.Q50637870
DNA replication and transcription direct a DNA strand bias in the process of targeted gene repair in mammalian cells.Q50798271
S-phase patterns of cyclin (PCNA) antigen staining resemble topographical patterns of DNA synthesis. A role for cyclin in DNA replication?Q53896160
Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAsQ24816245
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexesQ27860662
Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damageQ28646728
Manipulation of cell cycle progression can counteract the apparent loss of correction frequency following oligonucleotide-directed gene repairQ33272502
The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeastQ33305607
Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression.Q33850144
Oligonucleotide-mediated gene targeting in human hepatocytes: implications of mismatch repairQ34254706
Mechanisms underlying targeted gene correction using chimeric RNA/DNA and single-stranded DNA oligonucleotidesQ35026338
The involvement of replication in single stranded oligonucleotide-mediated gene repair.Q35215217
Gene therapy progress and prospects: targeted gene repairQ36091278
Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stressQ36513505
Progress and prospects: targeted gene alteration (TGA).Q36986953
Regulation of targeted gene repair by intrinsic cellular processesQ37389107
Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks.Q37501698
The checkpoint response to replication stressQ37501718
Maintaining genome stability at the replication forkQ37696954
Progress and prospects: oligonucleotide-directed gene modification in mouse embryonic stem cells: a route to therapeutic application.Q37821231
Targeted gene repair activates Chk1 and Chk2 and stalls replication in corrected cellsQ38316785
Enhanced gene repair mediated by methyl-CpG-modified single-stranded oligonucleotidesQ38349381
Subtle gene modification in mouse ES cells: evidence for incorporation of unmodified oligonucleotides without induction of DNA damageQ39684456
Parameters of oligonucleotide-mediated gene modification in mouse ES cellsQ39821715
DNA breakage associated with targeted gene alteration directed by DNA oligonucleotidesQ39848054
Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleasesQ39906804
Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombinationQ40156233
Recovery of cell cycle delay following targeted gene repair by oligonucleotidesQ40284701
Physical incorporation of a single-stranded oligodeoxynucleotide during targeted repair of a human chromosomal locusQ40377055
Reaction parameters of targeted gene repair in mammalian cellsQ40446636
Gene repair in mammalian cells is stimulated by the elongation of S phase and transient stalling of replication forks.Q40455619
Optimising gene repair strategies in cell cultureQ40729455
Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sitesQ41526470
P921main subjectDNA damageQ5205747
P304page(s)e18
P577publication date2012-04-03
P1433published inMolecular Therapy. Nucleic acidsQ27724110
P1476titleDNA damage response pathway and replication fork stress during oligonucleotide directed gene editing
P478volume1