Strain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies

scientific article published on 28 December 2010

Strain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.01034-10
P932PMC publication ID3067485
P698PubMed publication ID21189324

P50authorAntonio LanzavecchiaQ4776729
Jacques SimporeQ34176386
Giampietro CorradinQ80329128
Janine StubbsQ111535316
P2093author name stringBalam Saidou
Sope Olugbile
P2860cites workGenome sequence of the human malaria parasite Plasmodium falciparumQ22122524
Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motifQ28469255
Long-term clinical protection from falciparum malaria is strongly associated with IgG3 antibodies to merozoite surface protein 3.Q33305467
Sequence conservation in Plasmodium falciparum alpha-helical coiled coil domains proposed for vaccine developmentQ33459259
The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malariaQ33512926
Plasmodium falciparum merozoite surface protein 1 (MSP-1)-MSP-3 chimeric protein: immunogenicity determined with human-compatible adjuvants and induction of protective immune responseQ33613937
A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosusQ33842644
Effector function activities of a panel of mutants of a broadly neutralizing antibody against human immunodeficiency virus type 1Q33870167
Antibody responses to infections with strains of Plasmodium falciparum expressing diverse forms of merozoite surface protein 2.Q34006002
Specificity of the protective antibody response to apical membrane antigen 1Q34007362
In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic responseQ34260615
An epitope recognised by inhibitory monoclonal antibodies that react with a 51 kilodalton merozoite surface antigen in Plasmodium falciparumQ35096341
Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.Q35758478
Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodiesQ36227228
Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloningQ36459907
Antigenic differences and conservation among placental Plasmodium falciparum-infected erythrocytes and acquisition of variant-specific and cross-reactive antibodiesQ36789977
Plasmodium falciparum malaria: evidence for an isotype imbalance which may be responsible for delayed acquisition of protective immunityQ36943252
Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illnessQ37099503
Relationship between human immunodeficiency virus type 1 coinfection, anemia, and levels and function of antibodies to variant surface antigens in pregnancy-associated malariaQ37116542
Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated Plasmodium falciparum protein PFF0165cQ37451071
Strain-specific humoral response to a polymorphic malaria vaccineQ37582833
Natural selection on polymorphic malaria antigens and the search for a vaccineQ38952188
Serum IgG3 to the Plasmodium falciparum merozoite surface protein 2 is strongly associated with a reduced prospective risk of malariaQ39247931
High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal KenyaQ39362550
Protective immunization with invariant peptides of the Plasmodium falciparum antigen MSA2.Q39433305
Fcgamma receptor-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes in vitro.Q39515245
Plasmodium falciparum: a major role for IgG3 in antibody-dependent monocyte-mediated cellular inhibition of parasite growth in vitroQ39515257
Human antibody response to Plasmodium falciparum merozoite surface protein 2 is serogroup specific and predominantly of the immunoglobulin G3 subclassQ39823427
Regulation of antibody-dependent cellular cytotoxicity by IgG intrinsic and apparent affinity for target antigenQ40091335
Epidemiological correlation between levels of antibodies promoting merozoite phagocytosis of Plasmodium falciparum and malaria-immune statusQ40162910
A novel antibody-dependent cellular cytotoxicity mechanism involved in defense against malaria requires costimulation of monocytes FcgammaRII and FcgammaRIII.Q40168745
Cooperation between antibodies and monocytes that inhibit in vitro proliferation of Plasmodium falciparumQ40183845
Enhanced Plasmodium falciparum merozoite phagocytosis by monocytes from immune individualsQ40613128
High oxygen radical production is associated with fast parasite clearance in children with Plasmodium falciparum malariaQ40639357
Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stagesQ41835030
Structural and antigenic polymorphism of the 35- to 48-kilodalton merozoite surface antigen (MSA-2) of the malaria parasite Plasmodium falciparumQ41851051
Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytesQ42938913
Fcgamma receptor IIa (CD32) polymorphism is associated with protection of infants against high-density Plasmodium falciparum infection. VII. Asembo Bay Cohort ProjectQ43634113
Functional characterization of the antibody-mediated protection against blood stages of Plasmodium falciparum in the monkey Saimiri sciureusQ43872696
Inhibition of in vitro growth of plasmodium falciparum field isolates mediated by human antibodies to Pf155/RESA and Pf332.Q43935070
Geographical patterns of allelic diversity in the Plasmodium falciparum malaria-vaccine candidate, merozoite surface protein-2.Q43951122
46-53 kilodalton glycoprotein from the surface of Plasmodium falciparum merozoitesQ44542427
Association of Fcgamma receptor IIa (CD32) polymorphism with severe malaria in West Africa.Q46158460
Plasmodium falciparum: a rapid technique for genotyping the merozoite surface protein 2.Q46226747
Assessment of the role of the humoral response to Plasmodium falciparum MSP2 compared to RESA and SPf66 in protecting Papua New Guinean children from clinical malariaQ46227346
Opsonization as an effector mechanism in human protection against asexual blood stages of Plasmodium falciparum: Functional role of IgG subclassesQ46370720
Fc receptor but not complement binding is important in antibody protection against HIV.Q46545827
IgG3 antibodies to Plasmodium falciparum merozoite surface protein 2 (MSP2): increasing prevalence with age and association with clinical immunity to malaria.Q47830190
Differential effect and interaction of monocytes, hyperimmune sera, and immunoglobulin G on the growth of asexual stage Plasmodium falciparum parasitesQ47843178
Mice immunised with synthetic peptide from N-terminal conserved region of merozoite surface antigen-2 of human malaria parasite Plasmodium falciparum can control infection induced by Plasmodium yoelii yoelii 265BY strainQ47856201
Allelic polymorphisms in apical membrane antigen-1 are responsible for evasion of antibody-mediated inhibition in Plasmodium falciparumQ47864459
Cross-reactivity of antibody against an epitope of the Plasmodium falciparum second merozoite surface antigenQ47888814
Anti-MSP1 block 2 antibodies are effective at parasite killing in an allele-specific manner by monocyte-mediated antibody-dependent cellular inhibitionQ47897203
A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New GuineaQ47901914
Bacterially expressed and refolded receptor binding domain of Plasmodium falciparum EBA-175 elicits invasion inhibitory antibodies.Q47910023
Fcgamma receptor IIA and IIIB polymorphisms are associated with susceptibility to cerebral malariaQ47917458
An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirusQ47957009
Plasmodium falciparum strain-specific antibody blocks binding of infected erythrocytes to amelanotic melanoma cellsQ47976611
Induction of crisis forms in the human malaria parasite Plasmodium falciparum by gamma-interferon-activated, monocyte-derived macrophagesQ47982109
Opsonic activity of human immune serum on in vitro phagocytosis of Plasmodium falciparum infected red blood cells by monocytesQ47993075
Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trialQ48034345
Sequence comparison of allelic forms of the Plasmodium falciparum merozoite surface antigen MSA2.Q48246648
Structural diversity in the 45-kilodalton merozoite surface antigen of Plasmodium falciparumQ48273602
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectPlasmodium falciparumQ311383
antibodyQ79460
P304page(s)1143-1152
P577publication date2010-12-28
P1433published inInfection and ImmunityQ6029193
P1476titleStrain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies
P478volume79

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cites work (P2860)
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