LARGE enzyme activity deciphered: a new therapeutic target for muscular dystrophies

scientific article published on 29 March 2012

LARGE enzyme activity deciphered: a new therapeutic target for muscular dystrophies is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1043164968
P356DOI10.1186/GM322
P932PMC publication ID3446273
P698PubMed publication ID22458537
P5875ResearchGate publication ID223994421

P2093author name stringJane E Hewitt
P2860cites workDystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGEQ24301093
Mutant glycosyltransferase and altered glycosylation of alpha-dystroglycan in the myodystrophy mouseQ28589172
O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding.Q34090655
Dystroglycan: from biosynthesis to pathogenesis of human disease.Q36367346
Loss of alpha-dystroglycan laminin binding in epithelium-derived cancers is caused by silencing of LARGE.Q37160880
Receptor binding and cell entry of Old World arenaviruses reveal novel aspects of virus-host interaction.Q37424388
Dystroglycanopathies: coming into focusQ37852376
Enhanced laminin binding by alpha-dystroglycan after enzymatic deglycosylationQ38326990
Post-translational disruption of dystroglycan-ligand interactions in congenital muscular dystrophiesQ42524150
P433issue3
P304page(s)23
P577publication date2012-03-29
P1433published inGenome MedicineQ15816848
P1476titleLARGE enzyme activity deciphered: a new therapeutic target for muscular dystrophies
P478volume4

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cites work (P2860)
Q33930289Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans
Q41691404Comparative transcriptome analysis of muscular dystrophy models Large(myd), Dmd(mdx)/Large(myd) and Dmd(mdx): what makes them different?
Q39314908The transgenic expression of LARGE exacerbates the muscle phenotype of dystroglycanopathy mice

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