Isocitrate lyase supplies precursors for hydrogen cyanide production in a cystic fibrosis isolate of Pseudomonas aeruginosa

scientific article published on 21 August 2009

Isocitrate lyase supplies precursors for hydrogen cyanide production in a cystic fibrosis isolate of Pseudomonas aeruginosa is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.00692-09
P932PMC publication ID2753018
P698PubMed publication ID19700524

P2093author name stringLaura Silo-Suh
Jessica M Hagins
Robert Locy
P2860cites workCapsule polysaccharide is a bacterial decoy for antimicrobial peptides.Q54413052
Pseudomonas aeruginosa, cyanide accumulation and lung function in CF and non-CF bronchiectasis patientsQ60411857
Scavenging by alginate of free radicals released by macrophagesQ69340538
The effect of Pseudomonas alginate on rat alveolar macrophage phagocytosis and bacterial opsonizationQ69938806
Identification of the dadX gene coding for the predominant isozyme of alanine racemase in Escherichia coli K12Q69941165
Hydrogen cyanide production by Pseudomonas aeruginosa at reduced oxygen levelsQ70183747
Metabolism of urea and glyoxylate, degradative products of purines in marine animalsQ70482904
Bacterial cyanogenesis occurs in the cystic fibrosis lungQ81277161
Characterization of the hcnABC gene cluster encoding hydrogen cyanide synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0.Q24522179
Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patientsQ24551181
Cyanide production from glycine by a homogenate from a Pseudomonas speciesQ24643989
Glycine metabolism by Pseudomonas aeruginosa: hydrogen cyanide biosynthesisQ24655045
Oxygen, cyanide and energy generation in the cystic fibrosis pathogen Pseudomonas aeruginosaQ28267441
Virulence determinants from a cystic fibrosis isolate of Pseudomonas aeruginosa include isocitrate lyaseQ28492483
Use of cell wall stress to characterize sigma 22 (AlgT/U) activation by regulated proteolysis and its regulon in Pseudomonas aeruginosaQ28493041
Effect of rpoS mutation on the stress response and expression of virulence factors in Pseudomonas aeruginosaQ28493200
The transcriptional regulator AlgR controls cyanide production in Pseudomonas aeruginosaQ29346795
Chromosomal genetics of PseudomonasQ29615288
Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patientsQ29615301
Nitrogen redox balance in the cystic fibrosis airway: effects of antipseudomonal therapyQ30308607
Alginate lyase promotes diffusion of aminoglycosides through the extracellular polysaccharide of mucoid Pseudomonas aeruginosaQ33693064
Mechanism, regulation, and ecological role of bacterial cyanide biosynthesisQ33891094
Transcriptional control of the hydrogen cyanide biosynthetic genes hcnABC by the anaerobic regulator ANR and the quorum-sensing regulators LasR and RhlR in Pseudomonas aeruginosaQ33995036
Adaptations of Pseudomonas aeruginosa to the cystic fibrosis lung environment can include deregulation of zwf, encoding glucose-6-phosphate dehydrogenaseQ34124322
Organization and expression of the Escherichia coli K-12 dad operon encoding the smaller subunit of D-amino acid dehydrogenase and the catabolic alanine racemaseQ36105746
In vivo evidence of Pseudomonas aeruginosa nutrient acquisition and pathogenesis in the lungs of cystic fibrosis patientsQ36313798
Genetic mapping of chromosomal determinants for the production of the exopolysaccharide alginate in a Pseudomonas aeruginosa cystic fibrosis isolateQ36424054
Biochemical, genetic, and regulatory studies of alanine catabolism in Escherichia coli K12Q39132755
Pseudomonas aeruginosa PAO1 kills Caenorhabditis elegans by cyanide poisoningQ39529678
Stratified growth in Pseudomonas aeruginosa biofilmsQ40172940
Pseudomonas aeruginosa alginate in cystic fibrosis sputum and the inflammatory responseQ40428701
Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiologyQ42057512
Glycine and alanine dehydrogenase activities are catalyzed by the same protein in Mycobacterium smegmatis: upregulation of both activities under microaerophilic adaptationQ43912492
Development of tools for the genetic manipulation of Pseudomonas aeruginosaQ44964164
The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipaseQ48051501
Small broad-host-range gentamycin resistance gene cassettes for site-specific insertion and deletion mutagenesis.Q48094082
Insensitivity of D-amino acid dehydrogenase synthesis to catabolic repression in dadR mutants of Salmonella typhimuriumQ50229674
P433issue20
P921main subjecthydrogen cyanideQ26075
Pseudomonas aeruginosaQ31856
cystic fibrosisQ178194
P304page(s)6335-6339
P577publication date2009-08-21
P1433published inJournal of BacteriologyQ478419
P1476titleIsocitrate lyase supplies precursors for hydrogen cyanide production in a cystic fibrosis isolate of Pseudomonas aeruginosa
P478volume191

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cites work (P2860)
Q45366736Impact of D-amino acid dehydrogenase on virulence factor production by a Pseudomonas aeruginosa.
Q37695595Lethal Consequences of Overcoming Metabolic Restrictions Imposed on a Cooperative Bacterial Population
Q40480159Metabolic flux analyses of Pseudomonas aeruginosa cystic fibrosis isolates.
Q36873652Metabolite profiling to characterize disease-related bacteria: gluconate excretion by Pseudomonas aeruginosa mutants and clinical isolates from cystic fibrosis patients
Q56894595Residues Asn214, Gln211, Glu219 and Gln221 contained in the subfamily 3 catalytic signature of the isocitrate lyase from Pseudomonas aeruginosa are involved in its catalytic and thermal properties
Q42650446The deletion of TonB-dependent receptor genes is part of the genome reduction process that occurs during adaptation of Pseudomonas aeruginosa to the cystic fibrosis lung.
Q28492462Type III secretion system expression in oxygen-limited Pseudomonas aeruginosa cultures is stimulated by isocitrate lyase activity
Q42095929ald of Mycobacterium tuberculosis encodes both the alanine dehydrogenase and the putative glycine dehydrogenase

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