Regulation of plasma fructose and mortality in mice by the aldose reductase inhibitor lidorestat

scientific article published on 30 October 2008

Regulation of plasma fructose and mortality in mice by the aldose reductase inhibitor lidorestat is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/JPET.108.136283
P932PMC publication ID2682276
P698PubMed publication ID18974362
P5875ResearchGate publication ID23441936

P2093author name stringShunichi Homma
Ira J Goldberg
Hye-Lim Noh
Yunying Hu
Tae-Sik Park
Kazue Okajima
Andrew J Nichols
Thomas DiCioccio
P2860cites workHuman aldose reductase expression accelerates diabetic atherosclerosis in transgenic miceQ24530027
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Clinical usefulness of measuring urinary polyol excretion by gas-chromatography/mass-spectrometry in type 2 diabetes to assess polyol pathway activityQ31879944
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient miceQ32085363
Reaction of monosaccharides with proteins: possible evolutionary significanceQ33960984
A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.Q34330003
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Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?Q36001352
Glucose and diabetic vascular disease.Q36379991
Diabetic vascular disease: an experimental objectiveQ36500921
Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or progression to advanced plaques?Q36775094
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesionsQ37486465
Cloning and characterization of Leishmania mexicana fructose-1,6-bisphosphate aldolaseQ38967630
Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibitionQ40222083
Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathwayQ40729629
Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-ricQ41664275
Mitochondrial dysfunction accompanies diastolic dysfunction in diabetic rat heartQ42521720
Anesthetic inhibition in ischemic and nonischemic murine heart: comparison with conscious echocardiographic approachQ43572799
Aldose reductase activation is a key component of myocardial response to ischemiaQ43843299
Increased fructose concentrations in blood and urine in patients with diabetesQ43869416
Regulation of rat intestinal GLUT2 mRNA abundance by luminal and systemic factorsQ44466325
Dietary glycotoxins promote diabetic atherosclerosis in apolipoprotein E-deficient miceQ44474816
Induction of atherosclerosis by low-fat, semisynthetic diets in LDL receptor-deficient C57BL/6J and FVB/NJ mice: comparison of lesions of the aortic root, brachiocephalic artery, and whole aorta (en face measurement).Q44542257
Urinary sorbitol measurement and the effect of an aldose reductase inhibitor on its concentration in the diabetic stateQ44635139
Central role for aldose reductase pathway in myocardial ischemic injuryQ45000419
Effects of diabetes and CETP expression on diet-induced atherosclerosis in LDL receptor-deficient mice.Q45241682
Trehalose and 6-aminohexanoic acid stabilize and renature glucose-6-phosphate dehydrogenase inactivated by glycation and by guanidinium hydrochlorideQ46447820
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.Q46460053
Acute lipoprotein lipase deletion in adult mice leads to dyslipidemia and cardiac dysfunctionQ57396503
Mitochondrial dysfunction observed in situ in cardiomyocytes of rats in experimental diabetesQ68223509
Nonenzymatic glycation of bovine serum albumin by fructose (fructation). Comparison with the Maillard reaction initiated by glucoseQ69330169
Mannose, mannitol, fructose and 1,5-anhydroglucitol concentrations measured by gas chromatography/mass spectrometry in blood plasma of diabetic patientsQ71548944
Molecular Chaperones Protect Against Glycation-Induced Inactivation of Glucose-6-Phosphate DehydrogenaseQ71940499
Acute onset of diabetic pathological changes in transgenic mice with human aldose reductase cDNAQ72258241
An enzymatic fluorometric assay for fructoseQ73734924
Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathyQ79257400
Glycosylation mediates up-regulation of a potent antiangiogenic and proatherogenic protein, thrombospondin-1, by glucose in vascular smooth muscle cellsQ79441361
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)496-503
P577publication date2008-10-30
P1433published inJournal of Pharmacology and Experimental TherapeuticsQ1500272
P1476titleRegulation of plasma fructose and mortality in mice by the aldose reductase inhibitor lidorestat
P478volume328

Reverse relations

cites work (P2860)
Q37751655Aldose reductase and cardiovascular diseases, creating human-like diabetic complications in an experimental model.
Q34042977Fructose modulates cardiomyocyte excitation-contraction coupling and Ca²⁺ handling in vitro
Q42078154High fructose diet suppresses exercise-induced increase in AQP7 expression in the in vivo rat heart
Q35753067Human aldose reductase expression accelerates atherosclerosis in diabetic apolipoprotein E-/- mice
Q88643832Intestinal Absorption of Fructose
Q34549870Protective effects of astragaloside IV on db/db mice with diabetic retinopathy

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