Effects of acyl versus aminoacyl conjugation on the properties of antimicrobial peptides

scientific article published on June 2005

Effects of acyl versus aminoacyl conjugation on the properties of antimicrobial peptides is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.49.6.2412-2420.2005
P932PMC publication ID1140510
P698PubMed publication ID15917541

P2093author name stringLeonid Gaidukov
Arie Dagan
Shahar Rotem
Amram Mor
Fadia Zaknoon
Inna S Radzishevsky
P2860cites workRole of the hinge region and the tryptophan residue in the synthetic antimicrobial peptides, cecropin A(1-8)-magainin 2(1-12) and its analogues, on their antibiotic activities and structuresQ27627245
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The NH2-terminal alpha-helical domain 1-18 of dermaseptin is responsible for antimicrobial activityQ72739888
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Structure-activity relationship study of antimicrobial dermaseptin S4 showing the consequences of peptide oligomerization on selective cytotoxicityQ73413971
Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammationsQ73697723
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicityQ74038405
Development of protegrins for the treatment and prevention of oral mucositis: structure-activity relationships of synthetic protegrin analoguesQ74130341
N-terminal modifications of Polymyxin B nonapeptide and their effect on antibacterial activityQ74595394
Optimization of microbial specificity in cyclic peptides by modulation of hydrophobicity within a defined structural frameworkQ77080008
Bacteria-selective synergism between the antimicrobial peptides alpha-helical magainin 2 and cyclic beta-sheet tachyplesin I: toward cocktail therapyQ77295809
In vitro antibacterial properties of pexiganan, an analog of magaininQ28343235
Structure-function relationship of antibacterial synthetic peptides homologous to a helical surface region on human lactoferrin against Escherichia coli serotype O111.Q30032669
Inhibitory action of a truncated derivative of the amphibian skin peptide dermaseptin s3 on Saccharomyces cerevisiaeQ32022060
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Mechanisms of antimicrobial peptide action and resistanceQ34181099
Lantibiotics: biosynthesis and biological activities of uniquely modified peptides from gram-positive bacteriaQ34487933
Drosophila innate immunity: an evolutionary perspectiveQ34507042
Transgenic plants expressing cationic peptide chimeras exhibit broad-spectrum resistance to phytopathogensQ34511736
A chimeric peptide composed of a dermaseptin derivative and an RNA III-inhibiting peptide prevents graft-associated infections by antibiotic-resistant staphylococciQ35124472
Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity.Q35137651
The lipophosphoglycan of Leishmania parasitesQ35534721
Trichogin: a paradigm for lipopeptaibols.Q35601457
N-Acylated and D enantiomer derivatives of a nonamer core peptide of lactoferricin B showing improved antimicrobial activityQ39470734
N-terminal fatty acid substitution increases the leishmanicidal activity of CA(1-7)M(2-9), a cecropin-melittin hybrid peptideQ39478158
The protective effects of lactoferrin feeding against endotoxin lethal shock in germfree pigletsQ39570597
Sublethal concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in Escherichia coliQ39653098
Cationic hydrophobic peptides with antimicrobial activityQ39657941
Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resinQ39779042
An alpha-helical cationic antimicrobial peptide selectively modulates macrophage responses to lipopolysaccharide and directly alters macrophage gene expressionQ40856439
Role of the bactericidal/permeability-increasing protein in host defence.Q41729809
Acylation of SC4 dodecapeptide increases bactericidal potency against Gram-positive bacteria, including drug-resistant strainsQ42130359
Interactions of the designed antimicrobial peptide MB21 and truncated dermaseptin S3 with lipid bilayers: molecular-dynamics simulationsQ42255683
The vertebrate peptide antibiotics dermaseptins have overlapping structural features but target specific microorganisms.Q42282922
A novel linear amphipathic beta-sheet cationic antimicrobial peptide with enhanced selectivity for bacterial lipidsQ43607748
Conjugation of a magainin analogue with lipophilic acids controls hydrophobicity, solution assembly, and cell selectivityQ43883470
Direct interaction of dermaseptin S4 aminoheptanoyl derivative with intraerythrocytic malaria parasite leading to increased specific antiparasitic activity in cultureQ43950631
Direct comparison of membrane interactions of model peptides composed of only Leu and Lys residuesQ44415319
Tolaasins A--E, five new lipodepsipeptides produced by Pseudomonas tolaasiiQ44912133
Antimicrobial peptides are signaling moleculesQ46980434
Analysis of Membrane-Binding Properties of Dermaseptin Analogues: Relationships between Binding and CytotoxicityQ47407242
Dermaseptin, a peptide antibiotic, stimulates microbicidal activities of polymorphonuclear leukocytesQ47906935
Activity of dermaseptin K4-S4 against foodborne pathogensQ47956641
Structure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibioticsQ48010957
Combinatorial libraries: a tool to design antimicrobial and antifungal peptide analogues having lytic specificities for structure-activity relationship studies.Q52540321
Structural requirements for potent versus selective cytotoxicity for antimicrobial dermaseptin S4 derivatives.Q52545323
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectantimicrobial peptideQ1201508
P1104number of pages9
P304page(s)2412-2420
P577publication date2005-06-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleEffects of acyl versus aminoacyl conjugation on the properties of antimicrobial peptides
P478volume49

Reverse relations

cites work (P2860)
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