The mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione

scientific article published on 28 January 2015

The mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2015.01.027
P932PMC publication ID4332691
P698PubMed publication ID25637873
P5875ResearchGate publication ID271539721

P50authorEdmund R.S. KunjiQ60057975
Lee M BootyQ104465720
Michael P. MurphyQ37391317
Homa MajdQ42357017
Martin S KingQ56420802
Chancievan ThangaratnarajahQ58203115
P2093author name stringAndrew M James
P2860cites workCitrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondriaQ24291715
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Identification of the human mitochondrial S-adenosylmethionine transporter: bacterial expression, reconstitution, functional characterization and tissue distributionQ24301845
Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier familyQ24531883
Glutathione synthesisQ26864265
Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractylosideQ27642491
Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanismQ27681510
Identification of a novel gene encoding the yeast mitochondrial dicarboxylate transport protein via overexpression, purification, and characterization of its protein productQ27932590
Identification and functional expression of the mitochondrial pyruvate carrierQ27936768
Diseases caused by defects of mitochondrial carriers: a reviewQ28276275
Transport of glutathione across the mitochondrial membranesQ68722441
Enrichment and functional reconstitution of glutathione transport activity from rabbit kidney mitochondria: further evidence for the role of the dicarboxylate and 2-oxoglutarate carriers in mitochondrial glutathione transportQ73322860
Evidence for mitochondrial uptake of glutathione by dicarboxylate and 2-oxoglutarate carriersQ74527930
The mitochondrial transporter family SLC25: identification, properties and physiopathologyQ28282100
The mechanism of transport by mitochondrial carriers based on analysis of symmetryQ28300538
Yeast mitochondrial ADP/ATP carriers are monomeric in detergents as demonstrated by differential affinity purificationQ28306505
Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletionQ28576411
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione coupleQ29615232
Mitochondrial glutathione, a key survival antioxidantQ33649876
High-affinity transport of glutathione is part of a multicomponent system essential for mitochondrial functionQ33797751
A novel ADP/ATP transporter in the mitosome of the microaerophilic human parasite Entamoeba histolytica.Q33986679
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Yeast mitochondrial carriers: bacterial expression, biochemical identification and metabolic significance.Q34478978
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Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione.Q35659148
Hepatic mitochondrial transport of glutathione: studies in isolated rat liver mitochondria and H4IIE rat hepatoma cellsQ37342461
Origin and turnover of mitochondrial glutathioneQ37523709
Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modificationsQ37939954
Protection of NRK-52E cells, a rat renal proximal tubular cell line, from chemical-induced apoptosis by overexpression of a mitochondrial glutathione transporterQ40696111
Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line.Q40748964
Modulation of mitochondrial glutathione status and cellular energetics in primary cultures of proximal tubular cells from remnant kidney of uninephrectomized ratsQ42520867
Abundant bacterial expression and reconstitution of an intrinsic membrane-transport protein from bovine mitochondriaQ42812710
Functional expression of eukaryotic membrane proteins in Lactococcus lactis.Q43057811
Modulation of expression of rat mitochondrial 2-oxoglutarate carrier in NRK-52E cells alters mitochondrial transport and accumulation of glutathione and susceptibility to chemically induced apoptosisQ46807655
Identification by bacterial expression and functional reconstitution of the yeast genomic sequence encoding the mitochondrial dicarboxylate carrier proteinQ48056627
Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathiesQ48749128
Evidence that the rat hepatic mitochondrial carrier is distinct from the sinusoidal and canalicular transporters for reduced glutathione. Expression studies in Xenopus laevis oocytesQ49046818
The mitochondrial transporter familyQ56559223
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)621-628
P577publication date2015-01-28
P1433published inFEBS LettersQ1388051
P1476titleThe mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione
P478volume589

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