Connexin45 regulates endothelial-induced mesenchymal cell differentiation toward a mural cell phenotype

scientific article published on 6 December 2012

Connexin45 regulates endothelial-induced mesenchymal cell differentiation toward a mural cell phenotype is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1161/ATVBAHA.112.255950
P932PMC publication ID3737426
P698PubMed publication ID23220276

P2093author name stringJanis M Burt
Jennifer S Fang
Karen K Hirschi
Cuiping Dai
David T Kurjiaka
P2860cites workEndoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cellsQ24297899
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesisQ24610450
PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fateQ24683266
TGF-beta: from latent to activeQ28141342
Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient miceQ28361871
Molecular cloning and expression of rat connexin40, a gap junction protein expressed in vascular smooth muscleQ28576274
Connexin45 gap junction channels in rat cerebral vascular smooth muscle cellsQ28581528
Heart and head defects in mice lacking pairs of connexinsQ28587050
Defective vascular development in connexin 45-deficient miceQ28587341
Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out miceQ28594495
Intercellular Communication and the Control of Tissue Growth: Lack of Communication between Cancer CellsQ29027106
Gap junctions in the control of vascular functionQ30434810
Dye tracers define differential endothelial and smooth muscle coupling patterns within the arteriolar wallQ30465462
Connexin 43 and connexin 40 gap junctional proteins are present in arteriolar smooth muscle and endothelium in vivoQ30465475
Development of the aortic vessel wall as defined by vascular smooth muscle and extracellular matrix markersQ30469176
Selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylationQ30478921
Cx43 mediates TGF-beta signaling through competitive Smads binding to microtubulesQ30479504
Hindered diffusion through an aqueous pore describes invariant dye selectivity of Cx43 junctionsQ30481026
An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytesQ33862469
The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinitiesQ34186774
Characterization of the mitogen-activated protein kinase phosphorylation sites on the connexin-43 gap junction proteinQ34379889
Gap junctions and connexin-interacting proteinsQ35749955
Red light, green light: signals that control endothelial cell proliferation during embryonic vascular developmentQ35990192
Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communicationQ36328306
Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cellsQ36383154
Stimulus-Secretion Coupling in Vascular Endothelial CellsQ36570884
Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptorQ37376979
Connexin43 phosphorylation: structural changes and biological effectsQ37421795
Junctional intercellular communication and the control of growthQ37884714
Cellular mechanisms of TGF-beta actionQ37930633
Gap junctional channels are parts of multiprotein complexes.Q37971246
Fibronectin regulates latent transforming growth factor-beta (TGF beta) by controlling matrix assembly of latent TGF beta-binding protein-1.Q40464537
Immortalized connexin43 knockout cell lines display a subset of biological properties associated with the transformed phenotype.Q41090544
TGFbeta-induced RhoA activation and fibronectin production in mesangial cells require caveolaeQ41280741
Cardiac malformation in neonatal mice lacking connexin43.Q41358695
Characterization of gap junction channels in A7r5 vascular smooth muscle cellsQ41686409
Electron microscopic study of the prenatal development of the thoracic aorta in the rat.Q42519088
Scrape-loading and dye transfer. A rapid and simple technique to study gap junctional intercellular communicationQ43521106
Metabolic Coupling, Ionic Coupling and Cell ContactsQ44514347
Replacement by a lacZ reporter gene assigns mouse connexin36, 45 and 43 to distinct cell types in pancreatic islets.Q47190160
Expression of the connexin43- and connexin45-encoding genes in the developing and mature mouse inner ear.Q48032431
Junctional transfer of small molecules in cultured bovine brain microvascular endothelial cells and pericytesQ48210093
A quantitative analysis of connexin-specific permeability differences of gap junctions expressed in HeLa transfectants and Xenopus oocytesQ48945684
Smooth muscle lineage diversity in the chick embryo. Two types of aortic smooth muscle cell differ in growth and receptor-mediated transcriptional responses to transforming growth factor-beta.Q52199807
An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase constructQ72411299
Gap junction communication mediates transforming growth factor-beta activation and endothelial-induced mural cell differentiationQ73812170
Electrical conductance of mouse connexin45 gap junction channels is modulated by phosphorylationQ74059547
Phosphorylated carboxy terminal serine residues stabilize the mouse gap junction protein connexin45 against degradationQ74446675
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
cell differentiationQ210861
P304page(s)362-368
P577publication date2012-12-06
P1433published inArteriosclerosis, Thrombosis, and Vascular BiologyQ4797542
P1476titleConnexin45 regulates endothelial-induced mesenchymal cell differentiation toward a mural cell phenotype
P478volume33

Reverse relations

cites work (P2860)
Q54977104Cx43 Channel Gating and Permeation: Multiple Phosphorylation-Dependent Roles of the Carboxyl Terminus.
Q27011505Emerging roles of pericytes in the regulation of the neurovascular unit in health and disease
Q39332638Endothelial Progenitor Cells for the Vascularization of Engineered Tissues
Q40626597Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation
Q27008071Pericyte dynamics during angiogenesis: new insights from new identities
Q38374758Pericytes as targets in hereditary hemorrhagic telangiectasia.
Q39651330Poly(ethylene glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells
Q38650120Targeting vascular and leukocyte communication in angiogenesis, inflammation and fibrosis.
Q42552139The magic touch: endothelial cells muscle-up adipose
Q38154614Update on vascularization in tissue engineering
Q90216444Vascularization of Natural and Synthetic Bone Scaffolds
Q38225366We have contact: endothelial cell-smooth muscle cell interactions

Search more.