Effects of treatment with platinum azidothymidine and azidothymidine on telomerase activity and bcl-2 concentration in hepatocellular carcinoma- induced rats.

scientific article published on October 2014

Effects of treatment with platinum azidothymidine and azidothymidine on telomerase activity and bcl-2 concentration in hepatocellular carcinoma- induced rats. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID4224659
P698PubMed publication ID25414782

P2093author name stringShohreh Khatami
Asad Vaisi-Raygani
Mohammad Taghi Goodarzi
Masoud Taghizadeh-Jahed
Abdolreza Sabokrouh
P2860cites workThe human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeatsQ24339608
Human telomerase and its regulationQ24533247
Apoptosis: a review of programmed cell deathQ28305845
Telomeres and human disease: ageing, cancer and beyondQ29615353
Structure and function of telomeresQ29615759
Influence of p53 and bcl-2 on chemosensitivity in benign and malignant prostatic cell linesQ30783266
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesisQ33862956
Expression of the apoptosis-related genes BCL-2 and BAD in human breast carcinoma and their associated relationship with chemosensitivityQ34075056
An evolutionary review of human telomere biology: the thrifty telomere hypothesis and notes on potential adaptive paternal effectsQ34164417
Telomerase and cancerQ34188981
Bcl-2 family proteins as targets for anticancer drug designQ34293584
Telomerase regulation, cell cycle, and telomere stability in primitive hematopoietic cells.Q34431121
Telomeres, telomerase and senescenceQ34636650
Recent advances in telomere biology: implications for human cancer.Q35611262
Telomere diseasesQ36107376
Effect of bax, bcl-2 and bcl-xL on regulating apoptosis in tissues of normal liver and hepatocellular carcinomaQ36308391
BCL-2 family protein expression and platinum drug resistance in ovarian carcinomaQ36621123
Statins, Bcl-2, and apoptosis: cell death or cell protection?Q37188822
Correlation between chemosensitivity to anticancer drugs and Bcl-2 expression in gastric cancerQ37277833
Overexpression of Bcl-2 protects human hepatoma cells from Fas-antibody-mediated apoptosisQ38321543
A novel platinum compound inhibits telomerase activity in vitro and reduces telomere length in a human hepatoma cell lineQ38356726
Immunohistochemical evaluation of Bcl-2 gene family expression in liver of hepatitis C and cirrhotic patients: a novel mechanism to explain the high incidence of hepatocarcinoma in cirrhoticsQ38469468
Identification of Binding Mode of a Platinum (II) Complex, PtCl(2)(DIP), and Calf Thymus DNA.Q38833273
Effect of combined treatment with the epirubicin-incorporating micelles (NC-6300) and 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016) on a human gastric cancer modelQ39041944
DNA Interaction Studies of a New Platinum(II) Complex Containing Different Aromatic Dinitrogen LigandsQ39998591
DNA Interaction and DNA Cleavage Studies of a New Platinum(II) Complex Containing Aliphatic and Aromatic Dinitrogen LigandsQ40234199
Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivityQ40395982
Telomerase Inhibition Using Azidothymidine in the HT-29 Colon Cancer Cell LineQ40628938
Doses and time-dependent effects of 3'-azido-3'-deoxythymidine on T47D human breast cancer cells in vitroQ40843825
Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7.Q41038735
Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3'-azido-3'-deoxythymidine.Q41044843
Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissuesQ41235699
An informatics approach identifying markers of chemosensitivity in human cancer cell lines.Q42496234
Telomerase activity, telomere length and human telomerase reverse transcriptase expression in hepatocellular carcinoma is independent of hepatitis virus statusQ42989530
Nuclear translocation of telomerase reverse transcriptase: a critical process in chemical induced hepatocellular carcinogenesisQ43114767
Chronic in vitro exposure to 3'-azido-2', 3'-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cellsQ43549618
Simultaneous targeting of telomeres and telomerase as a cancer therapeutic approach.Q44302040
AZT-DNA interactionQ44833408
Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells.Q45186762
Anticarcinogenic effect and carcinogenic potential of the dietary phenolic acid: o-coumaric acidQ45360523
[Azidothymidine inhibition of telomerase activity and proliferation of TJ905 human glioblastoma cells].Q45941021
Chemoprevention of rat hepatocarcinogenesis with histone deacetylase inhibitors: efficacy of tributyrin, a butyric acid prodrug.Q46132555
Oxidative stress may enhance the malignant potential of human hepatocellular carcinoma by telomerase activationQ46164975
Cyclic induction of senescence with intermittent AZT treatment accelerates both apoptosis and telomere loss.Q46678519
Lack of correlation between P53 expression, BCL-2 expression, apoptosis and ex vivo chemosensitivity in advanced human breast cancer.Q52064760
Alternative methods of selecting rat hepatocellular nodules resistant to 2-acetylaminofluorene.Q54397062
BCL-2 antisense therapy in patients with non-Hodgkin lymphomaQ61868294
Selective inhibition of telomerase activity during terminal differentiation of immortal cell linesQ71254294
Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver diseaseQ73047915
The role of telomerase activity in hepatocellular carcinomaQ73531580
Telomerase activity in colorectal cancer and its relationship to bcl-2 expressionQ73747151
[Radiation-induced apoptosis and p53, bcl-2 gene expression products in QGY-7703 cell line in vitro]Q73910836
bcl-2 antisense therapy chemosensitizes human melanoma in SCID miceQ74165698
Telomerase activity and Bcl-2 expression in non-small cell lung cancerQ74216048
Expression profile of the putative catalytic subunit of the telomerase geneQ74251108
Usefulness of p53 protein, Bcl-2 protein and Ki-67 as predictors of chemosensitivity of malignant tumorsQ77325917
Telomerase activity in hepatocellular carcinoma and adjacent liver tissuesQ77658438
Telomerase activity and Bcl-2 expression in human breast cancerQ77702433
Azidothymidine treatment of hepatocellular carcinoma in rats: an in vivo study of telomerase inhibitionQ82176671
P433issue4
P921main subjectzidovudineQ198504
P304page(s)200-209
P577publication date2014-10-01
P1433published inAvicenna Journal of Medical BiotechnologyQ26842226
P1476titleEffects of treatment with platinum azidothymidine and azidothymidine on telomerase activity and bcl-2 concentration in hepatocellular carcinoma- induced rats
P478volume6

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cites work (P2860)
Q41661300Comparison between Platinum-Azidothymidine and Azidothymidine Effects on Bcl-2 and Telomerase Gene Expression in Rats with Hepatocellular Carcinoma
Q35959220Relationship between ADH2 Arg47His variation and hepatocellular carcinoma susceptibility: a meta analysis

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