The 3D structure of villin as an unusual F-Actin crosslinker

scientific article published on December 2008

The 3D structure of villin as an unusual F-Actin crosslinker is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.STR.2008.09.015
P932PMC publication ID2782859
P698PubMed publication ID19081064
P5875ResearchGate publication ID23661890

P50authorDavid J. DeRosierQ56866219
P2093author name stringJun Liu
Kenneth A Taylor
Dianne W Taylor
Cheri M Hampton
P2860cites workCloning of human erythroid dematin reveals another member of the villin familyQ24310645
Solution structures of the C-terminal headpiece subdomains of human villin and advillin, evaluation of headpiece F-actin-binding requirementsQ24337348
Structure of the N-terminal half of gelsolin bound to actin: roles in severing, apoptosis and FAFQ24563146
Villin sequence and peptide map identify six homologous domainsQ24653949
SWISS-MODEL: An automated protein homology-modeling serverQ24672647
Tropomyosin distinguishes between the two actin-binding sites of villin and affects actin-binding properties of other brush border proteinsQ24678498
NMR structure of an F-actin-binding "headpiece" motif from villinQ27620720
The calcium activation of gelsolin: insights from the 3A structure of the G4-G6/actin complexQ27640075
The NMR structure of dematin headpiece reveals a dynamic loop that is conformationally altered upon phosphorylation at a distal siteQ27642740
High-resolution cryo-EM structure of the F-actin-fimbrin/plastin ABD2 complexQ27649740
Structure of gelsolin segment 1-actin complex and the mechanism of filament severingQ27732041
NMR structure of the 35-residue villin headpiece subdomainQ27738191
The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleationQ27742885
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
EMAN: semiautomated software for high-resolution single-particle reconstructionsQ27860772
Villin function in the organization of the actin cytoskeleton. Correlation of in vivo effects to its biochemical activities in vitroQ28144138
High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activityQ28270683
Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a calcium-dependent mannerQ28275516
In vivo, villin is required for Ca(2+)-dependent F-actin disruption in intestinal brush bordersQ28593765
Low-resolution structure refinement in electron microscopy.Q30336303
MMTSB Tool Set: enhanced sampling and multiscale modeling methods for applications in structural biology.Q30341299
The CH-domain of calponin does not determine the modes of calponin binding to F-actinQ30440248
Actin filaments, stereocilia, and hair cells of the bird cochlea. II. Packing of actin filaments in the stereocilia and in the cuticular plate and what happens to the organization when the stereocilia are bentQ30494582
Improved transfer of two-dimensional crystals from the air/water interface to specimen support grids for high-resolution analysis by electron microscopyQ33415508
Formation of two-dimensional complexes of F-actin and crosslinking proteins on lipid monolayers: demonstration of unipolar alpha-actinin-F-actin crosslinkingQ34018879
Determination of the gelsolin binding site on F-actin: implications for severing and cappingQ34179951
Identification and organization of the components in the isolated microvillus cytoskeletonQ36201009
The organization of actin filaments in the stereocilia of cochlear hair cellsQ36201573
Refined structure of villin 14T and a detailed comparison with other actin-severing domainsQ36280403
An atomic model of actin filaments cross-linked by fimbrin and its implications for bundle assembly and functionQ36326402
Determination of the alpha-actinin-binding site on actin filaments by cryoelectron microscopy and image analysisQ36382938
Calcium control of the intestinal microvillus cytoskeleton: its implications for the regulation of microfilament organizationsQ36414241
In vivo analysis of functional domains from villin and gelsolinQ36531081
The isolated sixth gelsolin repeat and headpiece domain of villin bundle F-actin in the presence of calcium and are linked by a 40-residue unstructured sequence.Q37171330
Actin in the Brush-Border of Epithelial Cells of the Chicken IntestineQ37490061
Evidence for functional homology in the F-actin binding domains of gelsolin and alpha-actinin: implications for the requirements of severing and cappingQ42183113
Global structure changes associated with Ca2+ activation of full-length human plasma gelsolin.Q42625109
Solution structure of villin 14T, a domain conserved among actin-severing proteinsQ42843244
Structure of actin-containing filaments from two types of non-muscle cellsQ44785501
Identification of a functional switch for actin severing by cytoskeletal proteinsQ44844875
Targeted disruption of the mouse villin gene does not impair the morphogenesis of microvilli.Q52528810
Actin-dystrophin interface.Q54649929
F-actin is a helix with a random variable twistQ56937974
How to analyze electron micrographs of rafts of actin filaments crosslinked by actin-binding proteinsQ57356124
Characterisation of the F-actin binding domains of villin: classification of F-actin binding proteins into two groups according to their binding sites on actinQ57601970
Control of cytoplasmic actin gel–sol transformation by gelsolin, a calcium-dependent regulatory proteinQ59064148
The correlation averaging of a regularly arranged bacterial cell envelope proteinQ60191226
Localization of a new alpha-actinin binding site in the COOH-terminal part of actin sequenceQ68369360
Further characterization of a conserved actin-binding 27-kDa fragment of actinogelin and alpha-actinins and mapping of their binding sites on the actin molecule by chemical cross-linkingQ68962619
Differential localization of villin and fimbrin during development of the mouse visceral endoderm and intestinal epitheliumQ69557606
Further characterization of the alpha-actinin-actin interface and comparison with filamin-binding sites on actinQ70601153
Demonstration of at least two different actin-binding sites in villin, a calcium-regulated modulator of F-actin organizationQ71563258
Cysteine scanning mutagenesis at 40 of 76 positions in villin headpiece maps the F-actin binding site and structural features of the domainQ71614396
Role of fimbrin and villin in determining the interfilament distances of actin bundlesQ71656013
Ligand-induced conformational changes in villin, a calcium-controlled actin-modulating proteinQ71728052
Demonstration of three distinct calcium-binding sites in villin, a modulator of actin assemblyQ71728055
How actin filaments pack into bundlesQ72045597
Actin-binding proteins sensitively mediate F-actin bundle stiffnessQ80143400
Accurate marker-free alignment with simultaneous geometry determination and reconstruction of tilt series in electron tomographyQ81152336
Purification of muscle actinQ93859477
P433issue12
P304page(s)1882-1891
P577publication date2008-12-01
P1433published inStructureQ15709970
P1476titleThe 3D structure of villin as an unusual F-Actin crosslinker
P478volume16

Reverse relations

cites work (P2860)
Q37510793Actin bundling in plants.
Q50505065Arabidopsis VILLIN2 and VILLIN3 are required for the generation of thick actin filament bundles and for directional organ growth.
Q84971048ArabidopsisVILLIN1 and VILLIN3 Have Overlapping and Distinct Activities in Actin Bundle Formation and Turnover
Q38080358Biophysics of actin filament severing by cofilin
Q42726242Competition between intradomain and interdomain interactions: a buried salt bridge is essential for villin headpiece folding and actin binding.
Q33491904Electron tomography in life science
Q34468552Electron tomography of paracrystalline 2D arrays
Q28551064Gelsolin-Like Domain 3 Plays Vital Roles in Regulating the Activities of the Lily Villin/Gelsolin/Fragmin Superfamily
Q28077353Generation of intestinal surface: an absorbing tale
Q27657033How to Arm a Supervillin: Designing F-Actin Binding Activity into Supervillin Headpiece
Q49955492Identification of interfaces involved in weak interactions with application to F-actin-aldolase rafts
Q37496820Medaka villin 1-like protein (VILL) is associated with the formation of microvilli induced by decreasing salinities in the absorptive ionocytes
Q27324384Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping
Q27334078Molecular model of the microvillar cytoskeleton and organization of the brush border
Q38258023Plant villins: versatile actin regulatory proteins.
Q34095154Putting structure into context: fitting of atomic models into electron microscopic and electron tomographic reconstructions
Q37677924Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides
Q24312481The allosteric mechanism induced by protein kinase A (PKA) phosphorylation of dematin (band 4.9)
Q28300808The expanding superfamily of gelsolin homology domain proteins

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