Bone-seeking TRAP conjugates: surprising observations and their implications on the development of gallium-68-labeled bisphosphonates.

scientific article published on 30 March 2012

Bone-seeking TRAP conjugates: surprising observations and their implications on the development of gallium-68-labeled bisphosphonates. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1050288296
P356DOI10.1186/2191-219X-2-13
P932PMC publication ID3351026
P698PubMed publication ID22464278
P5875ResearchGate publication ID223992859

P50authorJan PlutnarQ53173465
Hans-Jürgen WesterQ128303541
P2093author name stringJohannes Notni
P2860cites workPET/CT imaging of osteoblastic bone metastases with (68)Ga-bisphosphonates: first human study.Q53315070
Positron flight in human tissues and its influence on PET image spatial resolutionQ53640691
67Ga binding to human serum proteins and tumor components.Q54185799
Comparison of iron-59, indium-111, and gallium-69 transferrin as a macromolecular tracer of vascular permeability and the transferrin receptorQ69754473
Gallium uptake by transferrin and interaction with receptor 1Q80307410
TRAP, a powerful and versatile framework for gallium-68 radiopharmaceuticalsQ82836384
Mechanisms of therapeutic activity for galliumQ28292030
Lanthanide(III) complexes of bis(phosphonate) monoamide analogues of DOTA: bone-seeking agents for imaging and therapyQ31142241
Complexation of metal ions with TRAP (1,4,7-triazacyclononane phosphinic acid) ligands and 1,4,7-triazacyclononane-1,4,7-triacetic acid: phosphinate-containing ligands as unique chelators for trivalent gallium.Q34119384
Osteogenesis imperfecta: questions and answersQ35012487
A comparison between bisphosphonates and other treatments for osteoporosisQ37781067
Bisphosphonates: molecular mechanisms of action and effects on bone cells, monocytes and macrophages.Q37781070
The relationship between the chemistry and biological activity of the bisphosphonates.Q37865849
Synthesis and evaluation of a novel 68Ga-chelate-conjugated bisphosphonate as a bone-seeking agent for PET imagingQ39461465
A triazacyclononane-based bifunctional phosphinate ligand for the preparation of multimeric 68Ga tracers for positron emission tomography.Q42167262
Thermodynamics of bisphosphonates binding to human bone: a two-site modelQ42571306
A bisphosphonate monoamide analogue of DOTA: a potential agent for bone targetingQ46817663
NMR investigations of the static and dynamic structures of bisphosphonates on human bone: a molecular modelQ46824743
P433issue1
P921main subjectgalliumQ861
P304page(s)13
P577publication date2012-03-30
P1433published inEJNMMI ResearchQ27723773
P1476titleBone-seeking TRAP conjugates: surprising observations and their implications on the development of gallium-68-labeled bisphosphonates
P478volume2

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cites work (P2860)
Q43595161A cyclen-based tetraphosphinate chelator for the preparation of radiolabeled tetrameric bioconjugates.
Q39332186A monoreactive bifunctional triazacyclononane phosphinate chelator with high selectivity for gallium-68.
Q46725531A shortcut to high-affinity Ga-68 and Cu-64 radiopharmaceuticals: one-pot click chemistry trimerisation on the TRAP platform
Q26849276Clinical applications of Gallium-68
Q39605627Comparative gallium-68 labeling of TRAP-, NOTA-, and DOTA-peptides: practical consequences for the future of gallium-68-PET.
Q48248853Dendritic poly-chelator frameworks for multimeric bioconjugation
Q28538187Development of novel radiogallium-labeled bone imaging agents using oligo-aspartic acid peptides as carriers
Q42630126Evaluation of Ga-DOTA-(D-Asp)n as bone imaging agents: D-aspartic acid peptides as carriers to bone.
Q53066975Gallium(III) complexes of NOTA-bis (phosphonate) conjugates as PET radiotracers for bone imaging.
Q64897716Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC.
Q31126059Investigations on the Ga(III) Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue
Q48149537MA-NOTMP: A Triazacyclononane Trimethylphosphinate Based Bifunctional Chelator for Gallium Radiolabelling of Biomolecules.
Q87980263Progress in Targeted Alpha-Particle Therapy. What We Learned about Recoils Release from In Vivo Generators

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