Proteolytic conversion of proinsulin into insulin. Identification of a Ca2+-dependent acidic endopeptidase in isolated insulin-secretory granules

scientific article published on September 1987

Proteolytic conversion of proinsulin into insulin. Identification of a Ca2+-dependent acidic endopeptidase in isolated insulin-secretory granules is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ2460279
P932PMC publication ID1148274
P698PubMed publication ID3318807
P5875ResearchGate publication ID19837122

P2093author name stringHutton JC
Davidson HW
Peshavaria M
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Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesiclesQ36216775
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A transplantable insulinoma in the ratQ37582132
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Enzymic processing of proparathyroid hormone by cell-free extracts of parathyroid glandsQ41312244
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Low-molecular-weight constituents of isolated insulin-secretory granules. Bivalent cations, adenine nucleotides and inorganic phosphateQ41791223
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Purification and characterization of enkephalin convertase, an enkephalin-synthesizing carboxypeptidase.Q42248575
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A human proinsulin variant at arginine 65Q59087022
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Effect of pH on conversion of proinsulin to insulin by a subcellular fraction of rat isletsQ69158290
On the Biosynthesis of Insulin in Anglerfish IsletsQ69180311
Studies on the conversion of proinsulin to insulin. 3. Studies in vitro with a crude secretion granule fraction isolated from rat islets of LangerhansQ69279164
Subcellular Localization of Proinsulin to Insulin Conversion in Isolated Rat IsletsQ69892066
Conversion of proinsulin to insulin in a subcellular fraction from rat isletsQ69922256
Carboxypeptidase activity in the insulin secretory granuleQ70163913
Cathepsin B-related proteases in the insulin secretory granuleQ70213567
The purified plasma membrane ATPase of the yeast Schizosaccharomyces pombe forms a phosphorylated intermediateQ70531214
Amounts and distribution of intracellular magnesium and calcium in pancreatic beta-cellsQ71450520
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectproteolysisQ33123
preproinsulinQ7240673
P304page(s)279-286
P577publication date1987-09-01
P1433published inBiochemical JournalQ864221
P1476titleProteolytic conversion of proinsulin into insulin. Identification of a Ca2+-dependent acidic endopeptidase in isolated insulin-secretory granules
P478volume246

Reverse relations

cites work (P2860)
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Q41513600Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones
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