Counteracting oxidative phosphorylation-mediated resistance of melanomas to MAPK pathway inhibition

scientific article published on 23 January 2015

Counteracting oxidative phosphorylation-mediated resistance of melanomas to MAPK pathway inhibition is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4161/23723556.2014.991610
P932PMC publication ID4905309
P698PubMed publication ID27308473
P5875ResearchGate publication ID273278919

P2093author name stringJennifer L McQuade
Yn Vashisht Gopal
P2860cites workLinks between metabolism and cancerQ24626229
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complexQ29617214
Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysisQ33946905
Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITFQ36793719
Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cellsQ37260512
Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanomaQ38949618
PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.Q39193337
Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cellsQ42478581
Targeting Oxidative Phosphorylation: Why, When, and HowQ43675822
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulationQ54398394
P433issue3
P921main subjectphosphorylationQ242736
P304page(s)e991610
P577publication date2015-01-23
P1433published inMolecular & cellular oncologyQ27725948
P1476titleCounteracting oxidative phosphorylation-mediated resistance of melanomas to MAPK pathway inhibition
P478volume2

Reverse relations

cites work (P2860)
Q92794476A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma
Q60960586Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas
Q52582838FBXW7 regulates a mitochondrial transcription program by modulating MITF.
Q90043581Melanoma Metabolism: Cell Survival and Resistance to Therapy
Q96304654Metabolic Plasticity of Melanoma Cells and Their Crosstalk With Tumor Microenvironment
Q47759599Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications.
Q37699251Whole-exome and transcriptome sequencing of refractory diffuse large B-cell lymphoma

Search more.