Increased expression of interleukin (IL)-35 and IL-17, but not IL-27, in gingival tissues with chronic periodontitis

scientific article published on 2 October 2014

Increased expression of interleukin (IL)-35 and IL-17, but not IL-27, in gingival tissues with chronic periodontitis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1902/JOP.2014.140293
P698PubMed publication ID25272982

P2093author name stringMakoto Mizutani
Hiroshi Nakamura
Makio Mogi
Akio Mitani
Norikazu Ohno
Toshihide Noguchi
Masami Hattori
Yoshinobu Tanaka
Wanda Niedbala
Kenichi Kurita
Yuichi Ishihara
Atsushi Abe
Naoya Higuchi
Shin Miyamae
Toshimitsu Hishikawa
Takeki Fujimura
P2860cites workDifferential expression of RANKL and osteoprotegerin in gingival crevicular fluid of patients with periodontitisQ47243804
Calibration of the Periotron 8000 and 6000 by polynomial regressionQ52217551
Oral administration of type-II collagen suppresses IL-17-associated RANKL expression of CD4+ T cells in collagen-induced arthritisQ53550619
Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis.Q54638927
IL-35 is a novel responsive anti-inflammatory cytokine--a new system of categorizing anti-inflammatory cytokinesQ21090933
Epstein–Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietinQ24320304
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cellsQ28214882
IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cellsQ28249077
The inhibitory cytokine IL-35 contributes to regulatory T-cell functionQ28258462
Interleukin-17 family members and inflammationQ28287876
The composition and signaling of the IL-35 receptor are unconventionalQ28589897
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brainQ29614225
The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone lossQ30513501
IL-12 family cytokines: immunological playmakersQ34153998
Periodontal diseases.Q34468885
IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10.Q34619702
Regulation of type 17 helper T-cell function by nitric oxide during inflammationQ35021942
Induction of regulatory Tr1 cells and inhibition of T(H)17 cells by IL-27.Q35592657
An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor-dependent signalsQ35804523
Host responses in periodontal diseases: current conceptsQ36056625
Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonistQ36417215
A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17.Q37249268
IL-12 family members in experimental colitisQ37349766
Destructive and protective roles of cytokines in periodontitis: a re-appraisal from host defense and tissue destruction viewpointsQ37782516
New directions in the basic and translational biology of interleukin-27Q37969347
Proinflammatory cytokines, aging, and age-related diseasesQ38116279
Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosionQ40590532
Cytokine responses of oral epithelial cells to Porphyromonas gingivalis infectionQ40842631
Risk indicators for future clinical attachment loss in adult periodontitis. Patient variablesQ41151799
Follicular dendritic cell-secreted protein is decreased in experimental periodontitis concurrently with the increase of interleukin-17 expression and the Rankl/Opg mRNA ratio.Q44823696
Over-expression of forkhead box P3 and its association with receptor activator of nuclear factor-kappa B ligand, interleukin (IL) -17, IL-10 and transforming growth factor-beta during the progression of chronic periodontitis.Q46023685
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectperiodontitisQ520127
P304page(s)301-309
P577publication date2014-10-02
P1433published inJournal of PeriodontologyQ6295732
P1476titleIncreased expression of interleukin (IL)-35 and IL-17, but not IL-27, in gingival tissues with chronic periodontitis
P478volume86

Reverse relations

cites work (P2860)
Q42362091Angiopoietin-like protein 2 regulates Porphyromonas gingivalis lipopolysaccharide-induced inflammatory response in human gingival epithelial cells.
Q55279570Association of Human Interleukin-35 Level in Gingival Crevicular Fluid and Serum in Periodontal Health, Disease, and after Nonsurgical Therapy: A Comparative Study.
Q53328950Downregulation of Proteinase-Activated Receptor-2, Interleukin-17, and Other Proinflammatory Genes by Subantimicrobial Doxycycline Dose in a Rat Periodontitis Model.
Q42320829Effect of interleukin (IL)-35 on IL-17 expression and production by human CD4+ T cells
Q90520062IL-35 and RANKL Synergistically Induce Osteoclastogenesis in RAW264 Mouse Monocytic Cells
Q36564664Interleukin-17A Gene Variability in Patients with Type 1 Diabetes Mellitus and Chronic Periodontitis: Its Correlation with IL-17 Levels and the Occurrence of Periodontopathic Bacteria.
Q45324167Interleukin-35 Suppresses Antiviral Immune Response in Chronic Hepatitis B Virus Infection
Q41197467Level of Interleukin-35 in Gingival Crevicular Fluid, Saliva, and Plasma in Periodontal Disease and Health.
Q36328094Periodontitis increases rheumatic factor serum levels and citrullinated proteins in gingival tissues and alter cytokine balance in arthritic rats
Q55280455Salivary Levels of IL-6 and IL-17 Could Be an Indicator of Disease Severity in Patients with Calculus Associated Chronic Periodontitis.
Q57040924Systemic treatment with resveratrol reduces the progression of experimental periodontitis and arthritis in rats
Q38617192T cells, teeth and tissue destruction - what do T cells do in periodontal disease?
Q91105567The cytokine network involved in the host immune response to periodontitis
Q38763612The osteoimmunology of alveolar bone loss
Q92686552The relationship between T-helper cell polarization and the RANKL/OPG ratio in gingival tissues from chronic periodontitis patients
Q95426672[Developments of neutrophil function and the relationship between neutrophils dysfunction and periodontitis]

Search more.