| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1035763507 |
| P356 | DOI | 10.1186/1471-2091-12-18 |
| P724 | Internet Archive ID | pubmed-PMC3103432 |
| P932 | PMC publication ID | 3103432 |
| P698 | PubMed publication ID | 21545744 |
| P5875 | ResearchGate publication ID | 51101324 |
| P50 | author | Jef D Boeke | Q37391166 |
| P2093 | author name string | Lixin Dai | |
| Qing Huang | |||
| P2860 | cites work | Initial sequencing and analysis of the human genome | Q21045365 |
| Hot L1s account for the bulk of retrotransposition in the human population | Q22066292 | ||
| The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools | Q24248165 | ||
| Ribonucleoprotein particle formation is necessary but not sufficient for LINE-1 retrotransposition | Q24336732 | ||
| Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors. | Q24540388 | ||
| 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro | Q24609215 | ||
| Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition | Q28114795 | ||
| Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma | Q28316436 | ||
| Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor | Q28323582 | ||
| Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs | Q28337739 | ||
| L-743, 726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase | Q28378789 | ||
| Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs | Q28742355 | ||
| Reverse Transcriptase Encoded by a Human Transposable Element | Q29618213 | ||
| High frequency retrotransposition in cultured mammalian cells | Q29618259 | ||
| Human LINE retrotransposons generate processed pseudogenes | Q29618327 | ||
| Human L1 retrotransposition: cis preference versus trans complementation | Q29618363 | ||
| LINE-mediated retrotransposition of marked Alu sequences | Q29618440 | ||
| Biology of mammalian L1 retrotransposons | Q29618630 | ||
| Nucleoside analogue reverse transcriptase inhibitors differentially inhibit human LINE-1 retrotransposition | Q33318459 | ||
| Sequence-specific single-strand RNA binding protein encoded by the human LINE-1 retrotransposon | Q33887614 | ||
| Defining the beginning and end of KpnI family segments | Q33939728 | ||
| Human L1 element target-primed reverse transcription in vitro | Q34207225 | ||
| HIV resistance to reverse transcriptase inhibitors | Q34291078 | ||
| Reverse transcription of retroviruses and LTR retrotransposons | Q34385549 | ||
| Characterization of L1 retrotransposition with high-throughput dual-luciferase assays | Q34559526 | ||
| L1 retrotransposition in nondividing and primary human somatic cells | Q34650044 | ||
| The human LINE-1 reverse transcriptase:effect of deletions outside the common reverse transcriptase domain | Q34671653 | ||
| Active retrotransposition by a synthetic L1 element in mice | Q35214717 | ||
| The LINE-1 DNA sequences in four mammalian orders predict proteins that conserve homologies to retrovirus proteins | Q36120853 | ||
| In vitro properties of the first ORF protein from mouse LINE-1 support its role in ribonucleoprotein particle formation during retrotransposition | Q36583469 | ||
| Anti-tumor activity of non-nucleosidic reverse transcriptase inhibitors. | Q36754680 | ||
| HIV-1 reverse transcriptase inhibitors | Q36763644 | ||
| LINE-1: a mammalian transposable element | Q38181068 | ||
| High-affinity, non-sequence-specific RNA binding by the open reading frame 1 (ORF1) protein from long interspersed nuclear element 1 (LINE-1). | Q38359167 | ||
| Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE-1 retrotransposon | Q39457323 | ||
| Inhibition of endogenous reverse transcriptase antagonizes human tumor growth. | Q40439570 | ||
| HIV‐1‐specific RT inhibitors: Highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptase | Q40486578 | ||
| Size and structure of the highly repetitive BAM HI element in mice | Q40492921 | ||
| Exposure of normal and transformed cells to nevirapine, a reverse transcriptase inhibitor, reduces cell growth and promotes differentiation | Q40647841 | ||
| Functional reverse transcriptase encoded by the human LINE-1 from baculovirus-infected insect cells | Q40662096 | ||
| Expression of an active form of recombinant Ty1 reverse transcriptase in Escherichia coli: a fusion protein containing the C-terminal region of the Ty1 integrase linked to the reverse transcriptase-RNase H domain exhibits polymerase and RNase H acti | Q41783121 | ||
| Kinetic studies with the non-nucleoside human immunodeficiency virus type-1 reverse transcriptase inhibitor U-90152E. | Q42275206 | ||
| Isolation of an active human transposable element | Q42614185 | ||
| Origin of the human L1 elements: proposed progenitor genes deduced from a consensus DNA sequence | Q42660978 | ||
| Cis-preferential LINE-1 reverse transcriptase activity in ribonucleoprotein particles | Q42688858 | ||
| A highly active synthetic mammalian retrotransposon | Q42828794 | ||
| Requirements for polyadenylation at the 3' end of LINE-1 elements | Q42834743 | ||
| Inhibition of reverse transcription in vivo by elevated manganese ion concentration | Q43733396 | ||
| Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon | Q44993880 | ||
| Metabolism of delavirdine, a human immunodeficiency virus type-1 reverse transcriptase inhibitor, by microsomal cytochrome P450 in humans, rats, and other species: probable involvement of CYP2D6 and CYP3A. | Q45754896 | ||
| DNA polymerization by the reverse transcriptase of the human L1 retrotransposon on its own template in vitro. | Q52664156 | ||
| The catalytic functions of chimeric reverse transcriptases of human immunodeficiency viruses type 1 and type 2 | Q67895173 | ||
| L1-mediated retrotransposition of murine B1 and B2 SINEs recapitulated in cultured cells | Q81741443 | ||
| P304 | page(s) | 18 | |
| P577 | publication date | 2011-05-05 | |
| P1433 | published in | BMC Biochemistry | Q15765786 |
| P1476 | title | Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition | |
| P478 | volume | 12 |
| Q92819740 | A potential new mechanism for pregnancy loss: considering the role of LINE-1 retrotransposons in early spontaneous miscarriage |
| Q33751005 | A role for retrotransposon LINE-1 in fetal oocyte attrition in mice |
| Q37589125 | A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines |
| Q56765662 | Activity of Retrotransposons in Stem Cells and Differentiated Cells |
| Q40296763 | Aging metabolism: intervention strategies |
| Q89859049 | Awakening the dark side: retrotransposon activation in neurodegenerative disorders |
| Q89637752 | Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication |
| Q60143966 | Contribution of Retrotransposable Elements to Aging |
| Q41951900 | Death by transposition - the enemy within? |
| Q41552071 | Development of a monoclonal antibody specific to the endonuclease domain of the human LINE-1 ORF2 protein |
| Q35894840 | Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes |
| Q28548473 | Efavirenz Has the Highest Anti-Proliferative Effect of Non-Nucleoside Reverse Transcriptase Inhibitors against Pancreatic Cancer Cells |
| Q47231567 | Endogenous LINE-1 (Long Interspersed Nuclear Element-1) Reverse Transcriptase Activity in Platelets Controls Translational Events Through RNA-DNA Hybrids |
| Q102059098 | High levels of LINE-1 transposable elements expressed in Kaposi's sarcoma-associated herpesvirus-related primary effusion lymphoma |
| Q28533274 | In vitro screening for compounds that enhance human L1 mobilization |
| Q57810301 | Inhibition of LINE-1 Retrotransposition by Capsaicin |
| Q37470888 | Inhibition of LINE-1 retrotransposon-encoded reverse transcriptase modulates the expression of cell differentiation genes in breast cancer cells. |
| Q33913579 | Intact piRNA pathway prevents L1 mobilization in male meiosis |
| Q35935123 | Interventions to Slow Aging in Humans: Are We Ready? |
| Q91387492 | L1 drives IFN in senescent cells and promotes age-associated inflammation |
| Q55692166 | L1 retrotransposition in the soma: a field jumping ahead. |
| Q28394080 | L1 retrotransposons, cancer stem cells and oncogenesis |
| Q46544707 | LINE-1 Retrotransposons in Healthy and Diseased Human Brain |
| Q38605923 | LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo |
| Q34468156 | LINE-1 induces hTERT and ensures telomere maintenance in tumour cell lines. |
| Q48659826 | LINE-1 retrotransposon copies are amplified during murine early embryo development |
| Q46854804 | LINE-1 retrotransposons: from 'parasite' sequences to functional elements |
| Q92251310 | LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation |
| Q37404117 | LINEs of evidence: noncanonical DNA replication as an epigenetic determinant |
| Q38611198 | Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs. |
| Q91637326 | Latent infection with Kaposi's sarcoma-associated herpesvirus enhances retrotransposition of long interspersed element-1 |
| Q34337046 | Long interspersed element-1 (LINE-1): passenger or driver in human neoplasms? |
| Q92046278 | Long interspersed element-1 ribonucleoprotein particles protect telomeric ends in alternative lengthening of telomeres dependent cells |
| Q64078047 | Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons |
| Q92711483 | Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity |
| Q40084589 | Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation |
| Q36371398 | Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer |
| Q33694621 | Repair of DNA double-strand breaks by templated nucleotide sequence insertions derived from distant regions of the genome |
| Q34170616 | Retrotransposition of long interspersed element 1 induced by methamphetamine or cocaine |
| Q26751314 | Roles for retrotransposon insertions in human disease |
| Q64258617 | Sources of Pathogenic Nucleic Acids in Systemic Lupus Erythematosus |
| Q26767214 | The Reverse Transcriptase Encoded by LINE-1 Retrotransposons in the Genesis, Progression, and Therapy of Cancer |
| Q55071546 | The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation. |
| Q34722563 | The specificity and flexibility of l1 reverse transcription priming at imperfect T-tracts |
| Q52609119 | Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response. |
| Q37445042 | Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues |
| Q37114645 | Viral protein R of human immunodeficiency virus type-1 induces retrotransposition of long interspersed element-1. |
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