Paraoxonase-1 is related to inflammation, fibrosis and PPAR delta in experimental liver disease

scientific article published on 14 January 2009

Paraoxonase-1 is related to inflammation, fibrosis and PPAR delta in experimental liver disease is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1002565542
P356DOI10.1186/1471-230X-9-3
P932PMC publication ID2632645
P698PubMed publication ID19144177

P50authorAnna RullQ41530405
Jorge JovenQ41878569
P2093author name stringJudit Marsillach
Jordi Camps
Natàlia Ferré
Bharti Mackness
Michael Mackness
Raul Beltran
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Two alleles of the human paraoxonase gene produce different amounts of mRNA. An explanation for differences in serum concentrations of paraoxonase associated with the (Leu-Met54) polymorphismQ73965887
Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and RQ77380948
Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidantsQ77416567
Tissue inhibitors of metalloproteinases, hepatic stellate cells and liver fibrosisQ77475942
Serum paraoxonase-1 in chronic alcoholics: relationship with liver diseaseQ79867587
Protective effect of soy isoflavones and activity levels of plasma paraoxonase and arylesterase in the experimental nonalcoholic steatohepatitis modelQ80127451
The development of human sera tests for HDL-bound serum PON1 and its lipolactonase activityQ80160399
Chromogenic and fluorogenic assays for the lactonase activity of serum paraoxonasesQ81576379
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Evaluation of low density array technology for quantitative parallel measurement of multiple genes in human tissueQ25257314
Peroxisome proliferator-activated receptor delta (PPARdelta) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosisQ28572042
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Chemokines in the pathogenesis of liver disease: so many players with poorly defined rolesQ35041594
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Peroxisome proliferator-activated receptor-delta, a regulator of oxidative capacity, fuel switching and cholesterol transportQ36660434
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Paraoxonase-1 inhibits oxidised LDL-induced MCP-1 production by endothelial cellsQ40555766
4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cellsQ42454202
The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 geneQ42517848
Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosisQ42552980
Purification and characterization of paraoxon hydrolase from rat liverQ42985351
Hepatic paraoxonase activity alterations and free radical production in rats with experimental cirrhosis.Q43736578
Serum paraoxonase activity: a new additional test for the improved evaluation of chronic liver damage.Q43862808
Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liverQ44457672
Comprehensive analysis of differential gene expression profiles on carbon tetrachloride-induced rat liver injury and regenerationQ46553079
Immunohistochemical analysis of paraoxonases-1, 2, and 3 expression in normal mouse tissuesQ46623909
Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasmaQ46742699
Transgene expression of human PON1 Q in mice protected the liver against CCl4-induced injuryQ46877614
Suppression of Pro-inflammatory Adhesion Molecules by PPAR-δ in Human Vascular Endothelial CellsQ57244183
Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient miceQ60321190
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Inhibition of hepatic cell nuclear DNA fragmentation by zinc in carbon tetrachloride-treated ratsQ60664727
The role of circulating monocyte chemoattractant protein-1 as a marker of hepatic inflammation in patients with chronic liver diseaseQ61945529
P304page(s)3
P577publication date2009-01-14
P1433published inBMC GastroenterologyQ15759922
P1476titleParaoxonase-1 is related to inflammation, fibrosis and PPAR delta in experimental liver disease
P478volume9