Multiple C-terminal serine phosphorylation accompanies both protein kinase C-dependent and -independent activation of cytosolic 85 kDa phospholipase A2 in macrophages.

scientific article published on July 1997

Multiple C-terminal serine phosphorylation accompanies both protein kinase C-dependent and -independent activation of cytosolic 85 kDa phospholipase A2 in macrophages. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ3250405
P932PMC publication ID1218574
P698PubMed publication ID9230120
P5875ResearchGate publication ID13989791

P50authorJonny WijkanderQ57028192
P2093author name stringE Holst
U Svensson
R Sundler
K Gewert
P2860cites workcPLA2 is phosphorylated and activated by MAP kinaseQ24314148
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Identification of phosphorylation sites of human 85-kDa cytosolic phospholipase A2 expressed in insect cells and present in human monocytesQ28279400
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAPQ28302244
Cytosolic phospholipase A2Q28609569
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acidQ33612950
Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesisQ36300832
Acyl-chain selectivity of the 85 kDa phospholipase A2 and of the release process in intact macrophagesQ41454404
An 100-kDa arachidonate-mobilizing phospholipase A2 in mouse spleen and the macrophage cell line J774. Purification, substrate interaction and phosphorylation by protein kinase C.Q41652409
The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cellsQ41691008
Purification of a phospholipase A2 from human monocytic leukemic U937 cells. Calcium-dependent activation and membrane associationQ41724497
A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7.Q41737705
Purification of a high-molecular-mass form of phospholipase A2 from rat kidney activated at physiological calcium concentrationsQ41825610
Dexamethasone down-regulates the 85 kDa phospholipase A2 in mouse macrophages and suppresses its activationQ41840771
A role for protein kinase C-mediated phosphorylation in the mobilization of arachidonic acid in mouse macrophagesQ43591506
Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C.Q47399343
Properties and purification of an arachidonoyl-hydrolyzing phospholipase A2 from a macrophage cell line, RAW 264.7.Q53728882
Epidermal growth factor enhances glomerular mesangial cell soluble phospholipase A2 activityQ67279865
Regulation of arachidonate-mobilizing phospholipase A2 by phosphorylation via protein kinase C in macrophagesQ67554795
A phospholipase A2 hydrolyzing arachidonoyl-phospholipids in mouse peritoneal macrophagesQ69182222
Evidence for a catalytic role of phospholipase A in phorbol diester- and zymosan-induced mobilization of arachidonic acid in mouse peritoneal macrophagesQ70288098
Regulation of phospholipase A2 activation by phosphorylation in mouse peritoneal macrophagesQ72571733
Thrombin-induced phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in human plateletsQ72639623
Phosphorylation and activation of the arachidonate-mobilizing phospholipase A2 in macrophages in response to bacteriaQ72966392
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)405-410
P577publication date1997-07-01
P1433published inBiochemical JournalQ864221
P1476titleMultiple C-terminal serine phosphorylation accompanies both protein kinase C-dependent and -independent activation of cytosolic 85 kDa phospholipase A2 in macrophages
P478volume325 ( Pt 2)

Reverse relations

cites work (P2860)
Q73412688Activation of arachidonate release and cytosolic phospholipase A2 via extracellular signal-regulated kinase and p38 mitogen-activated protein kinase in macrophages stimulated by bacteria or zymosan
Q42827313Atypical lambda/iota PKC conveys 5-lipoxygenase/leukotriene B4-mediated cross-talk between phospholipase A2s regulating NF-kappa B activation in response to tumor necrosis factor-alpha and interleukin-1beta
Q74028246Ca2+ -independent cytosolic phospholipase A in HL-60 cells differentiating to granulocytes
Q28198463Dexamethasone alters arachidonate release from human epithelial cells by induction of p11 protein synthesis and inhibition of phospholipase A2 activity
Q73106012Dexamethasone differentially regulates cytokine transcription and translation in macrophages responding to bacteria or okadaic acid
Q33242295Different roles for non-receptor tyrosine kinases in arachidonate release induced by zymosan and Staphylococcus aureus in macrophages
Q42469975Differential potentiation of arachidonic acid release by rat alpha2 adrenergic receptor subtypes
Q31400445Effects of dexamethasone on mitogen-activated protein kinases in mouse macrophages: implications for the regulation of 85 kDa cytosolic phospholipase A(2).
Q34198990Mammalian phospholipases A(2): mediators of inflammation, proliferation and apoptosis
Q33927870Recent advances in the regulation of cytosolic phospholipase A(2).

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