Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin.

scientific article published on May 2012

Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin. is …
instance of (P31):
case reportQ2782326
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.474
P932PMC publication ID3388189
P698PubMed publication ID22592113
P5875ResearchGate publication ID224971432

P50authorMichel CognéQ30118126
Christelle Vincent-FabertQ59678454
Pauline RouaudQ82266408
Virginie MagnoneQ106603832
P2093author name stringPierre Dubus
Yves Denizot
Rémi Fiancette
P2860cites workLoss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasiaQ28143642
Immune recognition of cyclin B1 as a tumor antigen is a result of its overexpression in human tumors that is caused by non-functional p53Q28217383
p53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesisQ33991429
Obesity and the Risk for a Hematological Malignancy: Leukemia, Lymphoma, or MyelomaQ35583755
Development of a murine model for blastoid variant mantle-cell lymphomaQ35828767
Novel targeted therapies for mantle cell lymphomaQ35889841
Advances in the understanding of mantle cell lymphomaQ37137955
The cytoskeleton and cancerQ37372562
The IgH 3' regulatory region and its implication in lymphomagenesis.Q37809817
The IgH locus 3' regulatory region: pulling the strings from behindQ37901616
A defect of the INK4-Cdk4 checkpoint and Myc collaborate in blastoid mantle cell lymphoma-like lymphoma formation in mice.Q53186236
A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.Q53279632
CDC20, a potential cancer therapeutic target, is negatively regulated by p53.Q55467766
Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse modelsQ73739514
The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotypeQ81464319
Murine model for mantle cell lymphomaQ82768873
P4510describes a project that useslimmaQ112236343
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)586-593
P577publication date2012-05-01
P1433published inOncotargetQ1573155
P1476titleMantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin
P478volume3

Reverse relations

cites work (P2860)
Q432083533'RR targeting in lymphomagenesis: a promising strategy?
Q43208235A new 3'RR regulatory role during lymphomagenesis
Q39185185CDK4 inhibition restores G(1)-S arrest in MYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage
Q41960162Efficient role of IgH 3' regulatory region deficient B-cells in the development of oil granulomas
Q61213179Elucidation of IgH 3' region regulatory role during class switch recombination via germline deletion.
Q92402170Eμ and 3'RR transcriptional enhancers of the IgH locus cooperate to promote c-myc-induced mature B-cell lymphomas
Q42103308Molecular dynamics of the full-length p53 monomer
Q98465710Mouse Models of c-myc Deregulation Driven by IgH Locus Enhancers as Models of B-Cell Lymphomagenesis
Q42910314Pre-germinal center origin for mature mouse B cell lymphomas: a major discrepancy with human mature lymphomas
Q37452977Somatic inactivation of Tp53 in hematopoietic stem cells or thymocytes predisposes mice to thymic lymphomas with clonal translocations
Q42256579Structure and Function of p53-DNA Complexes with Inactivation and Rescue Mutations: A Molecular Dynamics Simulation Study
Q34781391Targeting the oncogene B lymphoma deregulator IgH 3' regulatory region does not impede the in vivo inflammatory response in mice.
Q28075599The IgH 3' regulatory region and c-myc-induced B-cell lymphomagenesis
Q42434212The IgH 3' regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate.
Q41826032The IgH 3' regulatory region influences lymphomagenesis in Igλ-Myc mice
Q50098086The IgH 3'RR: Doctor Jekyll and Mister Hyde of B-cell maturation and lymphomagenesis
Q34619195The class-specific BCR tonic signal modulates lymphomagenesis in a c-myc deregulation transgenic model

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