Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain.

scientific article published on 27 March 2014

Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1008990092
P356DOI10.1038/GT.2014.28
P8608Fatcat IDrelease_ygocpa7zu5g7xdtvzlkwk2g5ue
P698PubMed publication ID24670994
P5875ResearchGate publication ID261138415

P50authorB T HarmonQ87525155
P2093author name stringL Padegimas
M J Cooper
O Sesenoglu-Laird
B L Waszczak
A E Aly
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Intranasal delivery of HMGB1 siRNA confers target gene knockdown and robust neuroprotection in the postischemic brain.Q35876200
Transgene expression in the striatum following intracerebral injections of DNA nanoparticles encoding for human glial cell line-derived neurotrophic factorQ36128982
DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice.Q36190772
Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous systemQ36464407
Organ distribution of transgene expression following intranasal mucosal delivery of recombinant replication-defective adenovirus gene transfer vectorQ36485052
Intranasal delivery of neural stem/progenitor cells: a noninvasive passage to target intracerebral gliomaQ36861449
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Pericyte-derived glial cell line-derived neurotrophic factor increase the expression of claudin-5 in the blood-brain barrier and the blood-nerve barrierQ39457264
Long-term transgene expression in the central nervous system using DNA nanoparticlesQ39505583
Peripheral nerve pericytes modify the blood-nerve barrier function and tight junctional molecules through the secretion of various soluble factorsQ39674615
Plasmid size up to 20 kbp does not limit effective in vivo lung gene transfer using compacted DNA nanoparticlesQ40307368
Optimization of hCFTR lung expression in mice using DNA nanoparticlesQ40309913
Intranasal administration of the growth-compromised HSV-2 vector DeltaRR prevents kainate-induced seizures and neuronal loss in rats and miceQ42382222
Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitutionQ42473767
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Improperly folded green fluorescent protein is secreted via a non-classical pathwayQ42810370
Nanoparticles of compacted DNA transfect postmitotic cellsQ44478822
P433issue5
P304page(s)514-521
P577publication date2014-03-27
P1433published inGene TherapyQ15763095
P1476titleIntranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain
P478volume21

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cites work (P2860)
Q38685603Biodegradable brain-penetrating DNA nanocomplexes and their use to treat malignant brain tumors
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Q92095826Focused ultrasound enhanced intranasal delivery of brain derived neurotrophic factor produces neurorestorative effects in a Parkinson's disease mouse model
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Q64869973Intranasal Delivery of pGDNF DNA Nanoparticles Provides Neuroprotection in the Rat 6-Hydroxydopamine Model of Parkinson's Disease
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Q38887870Pathophysiology Associated with Traumatic Brain Injury: Current Treatments and Potential Novel Therapeutics
Q38536735Recent prospective of surface engineered Nanoparticles in the management of Neurodegenerative disorders

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